Patents by Inventor Sarah-Luise Stergar

Sarah-Luise Stergar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for detecting gene modifications by means of asymmetrical PCR and blocking agents
    Patent number: 9115392
    Abstract: A method of detecting at least one gene modification such as a mutation in a gene includes carrying out an asymmetric polymerase chain reaction (PCR) with a combined use of at least one detectable mutation-specific hybridization probe (sensor probe) and at least one wild-type specific blocking agent which inhibits a binding of the at least one detectable mutation-specific hybridization probe (sensor probe) to a wild-type gene so as to provide at least one of a selective intensification and an amplification of a detection of a gene segment of a mutation gene having a gene modification.
    Type: Grant
    Filed: September 9, 2010
    Date of Patent: August 25, 2015
    Assignee: UNIVERSITAET DUISBURG-ESSEN
    Inventors: Martin Schuler, Frank Breitenbuecher, Sandra Hoffarth, Sarah-Luise Stergar
  • METHOD FOR DETECTING GENE MODIFICATIONS BY MEANS OF ASYMMETRICAL PCR AND BLOCKING AGENTS
    Publication number: 20120244538
    Abstract: A method of detecting at least one gene modification such as a mutation in a gene includes carrying out an asymmetric polymerase chain reaction (PCR) with a combined use of at least one detectable mutation-specific hybridization probe (sensor probe) and at least one wild-type specific blocking agent which inhibits a binding of the at least one detectable mutation-specific hybridization probe (sensor probe) to a wild-type gene so as to provide at least one of a selective intensification and an amplification of a detection of a gene segment of a mutation gene having a gene modification.
    Type: Application
    Filed: September 9, 2010
    Publication date: September 27, 2012
    Inventors: Martin Schuler, Frank Breitenbuecher, Sandra Hoffarth, Sarah-Luise Stergar