Patents by Inventor Sarah M. Ngola

Sarah M. Ngola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modification of metal nanoparticles for improved analyte detection by surface enhanced Raman spectroscopy (SERS)
    Patent number: 8003408
    Abstract: A SERS active particle having a metal-containing particle and a cationic coating on the metal-containing particle, wherein the SERS active particle carries a positive charge is disclosed. Also, a SERS active particle having a metal-containing particle and a non-metallic molecule, wherein the metal-containing particle is derivatized with the non-metallic molecule is disclosed. In addition, several methods of modifying the nanoparticles surfaces of a SERS active particle and of improving the interaction between the SERS active particle and an analyte are disclosed.
    Type: Grant
    Filed: December 29, 2005
    Date of Patent: August 23, 2011
    Assignee: Intel Corporation
    Inventors: Jingwu Zhang, Narayan Sundararajan, Sarah M. Ngola, Handong Li
  • SAMPLE PRESENTATION DEVICE
    Publication number: 20110070659
    Abstract: The present invention relates to sample presentation devices useful in performing analytical measurements. These devices have been configured to enable various aspects of liquid handling such as: retention, storage, transport, concentration, positioning, and transfer. Additionally, these devices can enhance the detection and characterization of analytes. The sample presentation devices of the present invention are comprised of one or more substrates having a plurality of zones of differing wettability. Methods of analyzing samples using the sample presentation device of the invention, as well as methods of making the sample presentation devices are disclosed.
    Type: Application
    Filed: May 24, 2010
    Publication date: March 24, 2011
    Applicant: Qiagen Sciences, Inc.
    Inventors: Christopher M. Belisle, John A. Walker, II, Sarah M. Ngola, Douglas P. Greiner, Mark J. Levy, Xiaoxia Zhao, Irene Y. Chen, Mark L. Stolowitz, Donald P. Paquin
  • Online analyte detection by surface enhanced Raman scattering (SERS)
    Patent number: 7605916
    Abstract: Devices and methods for separating and detecting analytes in a sample. The separation can be accomplished utilizing capillary electrophoresis (CE) or high-performance liquid chromatography (HPLC). The detection can be accomplished by surface enhanced Raman scattering.
    Type: Grant
    Filed: September 21, 2006
    Date of Patent: October 20, 2009
    Assignee: Intel Corporation
    Inventors: Jingwu Zhang, Sarah M. Ngola, Xing Su
  • Sample Presentation Device
    Publication number: 20080248589
    Abstract: The present invention relates to sample presentation devices useful in performing analytical measurements. These devices have been configured to enable various aspects of liquid handling such as: retention, storage, transport, concentration, positioning, and transfer. Additionally, these devices can enhance the detection and characterization of analytes. The sample presentation devices of the present invention are comprised of one or more substrates having a plurality of zones of differing wettability. Methods of analyzing samples using the sample presentation device of the invention, as well as methods of making the sample presentation devices are disclosed.
    Type: Application
    Filed: May 19, 2005
    Publication date: October 9, 2008
    Inventors: Christopher M. Belisle, John A. Walker, Sarah M. Ngola, Douglas P. Greiner, Mark J. Levy, Xiaoxia Zhao, Irene Y. Chen, Mark L. Stolowitz, Donald P. Paquin