Patents by Inventor Sarah NASRI

Sarah NASRI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • General Solid-Phase Synthesis of Crown Ethers
    Publication number: 20240400533
    Abstract: In a preferred embodiment, there is provided a method for preparing a crown ether, the method comprising: loading a resin having a resin functional group with a linking compound having a functional group selected for coupling to the resin functional group and at least two carbon atoms each having a substituent; coupling the linking compound to a polyethylene glycol having two terminal carbon atoms each bonded to an optionally protected terminal hydroxyl group to obtain a cyclized intermediate, whereby one said at least two carbon atoms or the substituent and an associated one of the two terminal carbon atoms or the hydroxyl groups undergo a coupling or substitution reaction; and removing the linking compound and the cyclized intermediate from the resin.
    Type: Application
    Filed: May 30, 2024
    Publication date: December 5, 2024
    Inventors: John F. TRANT, Sarah Nasri, John J. Hayward
  • Thermally sensitive protecting groups for cysteine for peptide cyclization and selective disulfide bond formation
    Patent number: 11746114
    Abstract: In a preferred embodiment, there is provided a protecting group for protecting the thiol side chain of a cysteine residue, the protecting group comprising a Diels-Alder cycloadduct of a furan and a maleimide, and optionally, a linker interposed between the thiol side chain and the Diels-Alder cycloadduct.
    Type: Grant
    Filed: February 4, 2022
    Date of Patent: September 5, 2023
    Inventors: John Frederick Trant, Sarah Nasri, Maryamalsadat Kosar, Sanaz Nadimi, Mohaddeseh Dashti Nejad Pour, Purshotam Sharma, Seyedeh Maryamdokht Taimoory
  • Thermally sensitive protecting groups for cysteine, and manufacture and use thereof
    Patent number: 11560387
    Abstract: In a preferred embodiment, there is provided a protecting group for protecting the thiol side chain of a cysteine residue, the protecting group comprising a Diels-Alder cycloadduct of a furan and a maleimide, and optionally, a linker interposed between the thiol side chain and the Diels-Alder cycloadduct.
    Type: Grant
    Filed: September 7, 2021
    Date of Patent: January 24, 2023
    Inventors: John Frederick Trant, Daniel Meister, Sarah Nasri, Anthony Emanuel Chifor, John James Hayward, Seyedeh Maryamdokht Taimoory, Mohadeseh Dashti-Pour
  • Thermally Sensitive Protecting Groups for Cysteine for Peptide Cyclization and Selective Disulfide Bond Formation
    Publication number: 20220153749
    Abstract: In a preferred embodiment, there is provided a protecting group for protecting the thiol side chain of a cysteine residue, the protecting group comprising a Diels-Alder cycloadduct of a furan and a maleimide, and optionally, a linker interposed between the thiol side chain and the Diels-Alder cycloadduct.
    Type: Application
    Filed: February 4, 2022
    Publication date: May 19, 2022
    Inventors: John Frederick TRANT, Sarah Nasri, Maryamalsadat Kosar, Sanaz Nadimi, Mohaddeseh Dashti Nejad Pour, Purshotam Sharma, Seyedeh Maryamdokht Taimoory
  • Thermally Sensitive Protecting Groups for Cysteine, and Manufacture and Use Thereof
    Publication number: 20210040105
    Abstract: In a preferred embodiment, there is provided a protecting group for protecting the thiol side chain of a cysteine residue, the protecting group comprising a Diels-Alder cycloadduct of a furan and a maleimide, and optionally, a linker interposed between the thiol side chain and the Diels-Alder cycloadduct.
    Type: Application
    Filed: August 5, 2020
    Publication date: February 11, 2021
    Inventors: John Frederick TRANT, Daniel MEISTER, Sarah NASRI, Anthony Emanuel CHIFOR, John HAYWARD, Seyedeh Maryamdokht TAIMOORY, Mohadeseh DASHTI-POUR