Abstract: A system for electroporation ablation including a catheter having an electrode assembly and one or more states. The electrode assembly may be in different shapes when the catheter is at different states. The controller is configured to generate, based on one or more models of electric fields, graphical representations of electric fields generated by the electrode assembly when the catheter is at different states. In some embodiments, the controller is configured to overlay the graphical representations of the one or more electric fields on an anatomical map of a patient.

Abstract: A system for ablation by electroporation including a catheter having electrodes, a display, and a controller. The controller is to generate, based on models of electric fields, graphical representations of the electric fields that can be produced using the electrodes, and overlay, on the display, the graphical representations of the electric fields and an anatomical map of a patient to aid in planning the ablation by electroporation, prior to delivering energy.

Abstract: Methods and systems for cardiac mapping are disclosed. An example system includes a catheter shaft with one or more electrodes coupled to a distal end of the catheter shaft. Electrodes sense electrical signals at anatomical locations within a heart. A processor coupled to the catheter shaft acquires electrogram signals of the heart using the electrodes. Each electrogram signal relates to three-dimensional positional data corresponding to the anatomical locations. The processor also store the electrogram signals of the heart corresponding to electrical activities sensed at corresponding anatomical locations, calculate an activation recovery interval associated with each of the corresponding anatomical locations, determine spatial gradient data of the activation recovery interval based on a distance between at least two neighboring anatomical locations.

Abstract: Methods and systems for cardiac mapping are disclosed. An example system includes a catheter shaft with one or more electrodes coupled to a distal end of the catheter shaft. Electrodes sense electrical signals at anatomical locations within a heart. A processor coupled to the catheter shaft acquires electrogram signals of the heart using the electrodes. Each electrogram signal relates to three-dimensional positional data corresponding to the anatomical locations. The processor also store the electrogram signals of the heart corresponding to electrical activities sensed at corresponding anatomical locations, calculate an activation recovery interval associated with each of the corresponding anatomical locations, determine spatial gradient data of the activation recovery interval based on a distance between at least two neighboring anatomical locations.

Abstract: Methods and systems for cardiac mapping are disclosed. An example system includes a catheter shaft with one or more electrodes coupled to a distal end of the catheter shaft. Electrodes sense electrical signals at anatomical locations within a heart. A processor coupled to the catheter shaft acquires electrogram signals of the heart using the electrodes. Each electrogram signal relates to three-dimensional positional data corresponding to the anatomical locations. The processor also store the electrogram signals of the heart corresponding to electrical activities sensed at corresponding anatomical locations, calculate an activation recovery interval associated with each of the corresponding anatomical locations, determine spatial gradient data of the activation recovery interval based on a distance between at least two neighboring anatomical locations.

Abstract: Methods and systems for cardiac mapping are disclosed. An example system includes a catheter shaft with one or more electrodes coupled to a distal end of the catheter shaft. Electrodes sense electrical signals at anatomical locations within a heart. A processor coupled to the catheter shaft acquires electrogram signals of the heart using the electrodes. Each electrogram signal relates to three-dimensional positional data corresponding to the anatomical locations. The processor also store the electrogram signals of the heart corresponding to electrical activities sensed at corresponding anatomical locations, calculate an activation recovery interval associated with each of the corresponding anatomical locations, determine spatial gradient data of the activation recovery interval based on a distance between at least two neighboring anatomical locations.

Abstract: A catheter system includes a catheter and a control system. The catheter includes an elongate catheter body and a catheter tip coupled to a distal end of the elongate catheter body. The catheter tip includes a plurality of openings corresponding to a plurality of lumens extending through the elongate catheter body. The control system is configured to initiate a source of vacuum pressure to at least one of the plurality of lumens, receive an indication of a vacuum seal, and in response to the indication of the vacuum seal, initiate a source of ablation energy.

Abstract: A catheter system includes a catheter with an elongate catheter body, a catheter tip coupled to a distal end of the catheter body, and at least one light-emitting element configured to emit light to excite flavin adenine dinucleotide (FAD) molecules. The catheter system further including at least one light sensor configured to sense a light emitted by the excited FAD molecules.

Abstract: Catheters and methods are provided for determining a fluid flow rate of fluid located near a tip assembly of the catheter and providing an indication of the fluid flow condition and/or controlling one or more functions of the catheter based on the determined fluid rate. A method includes receiving a signal from a sensor located on a tip assembly of a catheter, the signal being indicative of a fluid flow condition of fluid located near the tip assembly. A processing device determines the fluid flow condition using the signal. Based on the determined fluid flow rate, the processor causes a device to output an indication of the determined fluid flow condition.