Patents by Inventor Sarah Skye McNees

Sarah Skye McNees has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OLIVETOLIC ACID CYCLASE VARIANTS AND METHODS FOR THEIR USE
    Publication number: 20240052332
    Abstract: Described herein are non-natural olivetolic acid cyclases (OAC) variants capable of forming a 2,4-dihydroxy-6-alkylbenzoic acid from a 3,5,7-trioxoacyl-CoA or a 3,5,7-trioxocarboxylate substrate at a greater rate than a wild type or control OAC. The non-natural OAC (and OLS) can be expressed in an engineered cell having a pathway to form cannabinoids, which include CBGA, its analogs and derivatives. CBGA can be used for the preparation of cannabigerol (CBG), which can be used in therapeutic compositions.
    Type: Application
    Filed: December 8, 2021
    Publication date: February 15, 2024
    Inventors: Michael A. Noble, Sarah Skye McNees, Darlene Jan Abcede Usi, Joseph R. Warner