Abstract: A GNSS data collection system includes a pole mounted GNSS receiver and inclination sensors. The range pole has an adjustable length and an integrated electronic measurement device to capture and provide length data. A data collection module provides a data collection graphical user interface (GUI) visible on a hand-held data collector computer. The data collector computer is communicably coupled to the GNSS receiver and/or the electronic measurement device and receives three-dimensional location data, the length data, and inclination data for the range pole in real-time. The inclination data and height of the range pole are used to calculate and display horizontal distance and direction to level the GNSS receiver.

Abstract: A Robotic Total Station (RTS) system includes an RTS disposed for at least two-axis rotation on a tripod, and a rover including a pole mounted prism and GNSS receiver with inclination sensors. The RTS rotates on the tripod to point towards the rover and generate an RTS-position measurement using an optical signal reflected by the prism. The RTS is communicably coupled to the data collector and/or the GNSS receiver, and receives and uses the GNSS-derived position measurements and the inclination data for the range pole in real-time, to automatically track and point the RTS towards the prism.

Abstract: A GNSS data collection system includes a pole mounted GNSS receiver and inclination sensors. The range pole has an adjustable length and an integrated electronic measurement device to capture and provide length data. A data collection module provides a data collection graphical user interface (GUI) visible on a hand-held data collector computer. The data collector computer is communicably coupled to the GNSS receiver and/or the electronic measurement device and receives three-dimensional location data, the length data, and inclination data for the range pole in real-time. The inclination data and height of the range pole are used to calculate and display horizontal distance and direction to level the GNSS receiver.

Abstract: The inventors report two siblings presenting recurrent EBV infection and Hodgkin lymphoma caused by a homozygous loss-of-function mutation in RASGRP1, a T-cell specific nucleotide exchange factor (GEF) known to activate the RAS-induced MAPK/ERK kinases pathway. In response to TCR stimulation, RASGRP1-deficient T cells exhibited defective ERK kinases activation and impaired proliferation that was restored by expression of wild-type RASGRP1. Thus, these results identify a novel primary immunodeficiency that highlights T-cell proliferation and offers the opportunity to develop RASGRP1 inhibitor for inhibiting T cell proliferation in a subject in need thereof.

Abstract: A Robotic Total Station (RTS) system includes an RTS disposed for at least two-axis rotation on a tripod, and a rover including a pole mounted prism and GNSS receiver with inclination sensors. The RTS rotates on the tripod to point towards the rover and generate an RTS-position measurement using an optical signal reflected by the prism. The RTS is communicably coupled to the data collector and/or the GNSS receiver, and receives and uses the GNSS-derived position measurements and the inclination data for the range pole in real-time, to automatically track and point the RTS towards the prism.

Abstract: A GNSS data collection system includes a pole mounted GNSS receiver and inclination sensors. A data collection module provides a data collection graphical user interface (GUI) visible on a hand-held data collector computer. The data collector computer is communicably coupled to the GNSS receiver and receives three-dimensional location data and inclination data for the range pole in real-time. A virtual level component uses the inclination data to display on the GUI real-time tilt information in the form of a virtual bubble level indicator. The inclination data and height of the range pole are used to calculate and display horizontal distance and direction to level the GNSS receiver, using: incline=a cos(cos(x_tilt)*cos(y_tilt)) where, xtilt=the inclination data for the range pole along the x axis, ytilt=the inclination data for the range pole along the y axis, and horizontaldistancefromlevel=rh*sin(incline) where, rh=the height of the range pole.

Abstract: A media pick method includes receiving an initiation signal, causing a media pick system to complete a series of wait, forward move and reverse move pick actions, and causing the media pick system to complete the last of the series of forward move pick actions in conjunction with a feed roll motor's de-skew move. Reversing a direction of a pick motor enables a gear train to reset and allow momentum to build before engaging the paper on a second forward pick try. Repeats of pick pulses applies a proper balance of shear and normal forces on media.