Patents by Inventor Sarah Wootton

Sarah Wootton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENGINEERED NEWCASTLE DISEASE VIRUS VECTOR AND USES THEREOF
    Publication number: 20220396809
    Abstract: An engineered Newcastle Disease Virus (NDV) vector is provided. In particular, the present disclosure provides methods of treating or preventing a disease such as cancer, or an infectious disease, or methods for eliciting an immune response, with the engineered NDV vector. The engineered NDV vector provided herein is useful as an immunogenic composition, an oncolytic agent, or a vaccine.
    Type: Application
    Filed: June 3, 2022
    Publication date: December 15, 2022
    Inventors: Sarah Wootton, Leonardo Susta, Byram Bridle, Pierre Major, Lisa Santry, Yanlong Pei
  • Adeno-associated virus particle with mutated capsid and methods of use thereof
    Patent number: 10806802
    Abstract: A recombinant adeno-associated virus (rAAV) particle with a mutated capsid protein is provided. In particular, the present disclosure provides methods of delivering a therapeutic agent to a muscle, airway, liver, central nervous system, retina or lung cell in a subject, and methods of treating or preventing infectious, acquired or genetic disease, with said rAAV particle.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: October 20, 2020
    Assignees: University of Guelph, Ottawa Hospital Research Institute
    Inventors: Sarah Wootton, Laura van Lieshout, Bernard Claude Frank Thebaud, Martin Hubert Kang
  • METHODS FOR REGULATING ENDOGENOUS PRODUCTION OF ANTIBODIES AGAINST INFECTIOUS DISEASES
    Publication number: 20200148762
    Abstract: The present disclosure relates to the composition of one or more agents, therapies, treatments, and methods of use of the agents and/or therapies and/or treatments for upregulating production of two or more antibodies, one or more bi-specific antibodies, or combinations thereof. Embodiments of the present disclosure can be used as a therapy or a treatment of a conditions including: sepsis, parasites, and active and chronic infections caused by bacteria, non-hemorrhagic viruses, amoeba, mycoplasma, fungus, prions or combinations thereof.
    Type: Application
    Filed: November 9, 2018
    Publication date: May 14, 2020
    Inventors: Laura Van Lieshout, Sarah Wootton, Bradley G. Thompson
  • ADENO-ASSOCIATED VIRUS PARTICLE WITH MUTATED CAPSID AND METHODS OF USE THEREOF
    Publication number: 20190216949
    Abstract: A recombinant adeno-associated virus (rAAV) particle with a mutated capsid protein is provided. In particular, the present disclosure provides methods of delivering a therapeutic agent to a muscle, airway, liver, central nervous system, retina or lung cell in a subject, and methods of treating or preventing infectious, acquired or genetic disease, with said rAAV particle.
    Type: Application
    Filed: January 18, 2019
    Publication date: July 18, 2019
    Inventors: Sarah Wootton, Laura van Lieshout, Bernard Claude Frank Thebaud, Martin Hubert Kang