Patents by Inventor Sarah Wright

Sarah Wright has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR THE TARGETING OF PCSK9
    Publication number: 20240123089
    Abstract: Provided herein are gene repressor systems comprising fusion proteins, such as fusion proteins comprising a DNA binding domain such as a TALE, zinc finger or catalytically-dead CRISPR protein and guide nucleic acid (gRNA), which are useful in the repression of a proprotein convertase subtilisin kexin Type 9 (PCSK9) gene. Also provided are methods of using such systems to repress transcription of PCSK9.
    Type: Application
    Filed: November 21, 2023
    Publication date: April 18, 2024
    Inventors: Jason FERNANDES, Sean HIGGINS, Sarah DENNY, Ross WHITE, Emeric Jean Marius CHARLES, Addison WRIGHT, Benjamin DEMAREE, Manuel MOHR, Wenyuan ZHOU, Benjamin OAKES
  • COMPOSITIONS AND METHODS FOR THE TARGETING OF PCSK9
    Publication number: 20240124537
    Abstract: Provided herein are gene repressor systems comprising fusion proteins, such as fusion proteins comprising a DNA binding domain such as a TALE, zinc finger or catalytically-dead CRISPR protein and guide nucleic acid (gRNA), which are useful in the repression of a proprotein convertase subtilisin/kexin Type 9 (PCSK9) gene. Also provided are methods of using such systems to repress transcription of PCSK9.
    Type: Application
    Filed: November 21, 2023
    Publication date: April 18, 2024
    Inventors: Jason FERNANDES, Sean HIGGINS, Sarah DENNY, Ross WHITE, Emeric Jean Marius CHARLES, Addison WRIGHT, Benjamin DEMAREE, Manuel MOHR, Wenyuan ZHOU, Benjamin OAKES
  • CONDUCTIVE CONNECTIONS
    Publication number: 20230234364
    Abstract: Examples of conductive connections are described herein. Some examples of a fluid ejection device may include an electrically conductive non-metal structure in contact with fluid in a fluid reservoir. Some examples of the fluid ejection device may include conductive adhesive forming a conductive connection between the electrically conductive non-metal structure and circuitry.
    Type: Application
    Filed: April 16, 2020
    Publication date: July 27, 2023
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Eleanor Sarah Wright, Sean Mathew Instasi
  • ELECTRICALLY CONDUCTIVE STRUCTURES
    Publication number: 20230137179
    Abstract: Examples of fluid reservoirs are described herein. In some examples, a fluid reservoir includes a routing. In some examples, the fluid reservoir includes a structure contacting the routing. In some examples, the structure contacts fluid in the fluid reservoir. In some examples, the structure includes carrier material and electrically conductive non-metal material.
    Type: Application
    Filed: March 30, 2020
    Publication date: May 4, 2023
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: John L. Taylor, Scott Sayer, Eleanor Sarah Wright
  • Use of perlecan domain V in treating amyloidogenic disease
    Patent number: 9358273
    Abstract: The application reports that perlecan domain V (DV) or the LG3 domain thereof reduces deposition and toxicity of A? peptide, the major component of plaques in Alzheimer's disease. Methods of using DV, LG3 and related molecules in treatment of amyloidogenic diseases, particularly Alzheimer's disease, are provided.
    Type: Grant
    Filed: January 6, 2011
    Date of Patent: June 7, 2016
    Assignee: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: Gregory J. Bix, Sarah Wright, Irene Griswold-Prenner
  • USE OF PERLECAN DOMAIN V IN TREATING AMYLOIDOGENIC DISEASE
    Publication number: 20130036481
    Abstract: The application reports that perlecan domain V (DV) or the LG3 domain thereof reduces deposition and toxicity of A? peptide, the major component of plaques in Alzheimer's disease. Methods of using DV, LG3 and related molecules in treatment of amyloidogenic diseases, particularly Alzheimer's disease, are provided.
    Type: Application
    Filed: January 6, 2011
    Publication date: February 7, 2013
    Applicant: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: Gregory J. Bix, Sarah Wright, Irene Griswold-Prenner
  • Methods of inhibiting amyloid toxicity
    Patent number: 7901683
    Abstract: The present invention features methods and compositions for inhibiting amyloidogenic protein toxicity, inhibiting formation of an amyloidogenic protein deposit and/or treating amyloidogenic diseases by administering a pharmaceutically effective amount of one or more agents that bind an integrin or an integrin subunit.
    Type: Grant
    Filed: December 16, 2008
    Date of Patent: March 8, 2011
    Assignee: Elan Pharmaceuticals, Inc.
    Inventors: Irene Griswold-Prenner, Sarah Wright, Theodore Yednock, Russell Rydel
  • SIGNALING INTERMEDIATES IN AN IN VITRO MODEL OF ALZHEIMER'S DISEASE
    Publication number: 20100303824
    Abstract: The invention provides a novel human protein, FISH adaptor protein, involved in amyloid ?-protein-mediated cell death. Also provided are methods for modulating amyloid ?-protein-mediated cell death using agents that interfere with the activity of FISH adaptor protein.
    Type: Application
    Filed: January 26, 2010
    Publication date: December 2, 2010
    Applicant: ELAN PHARMACEUTICALS, INC.
    Inventors: NIKOLAY MALININ, MAILE SKOMP, SARAH WRIGHT, IRENE GRISWOLD-PRENNER
  • Methods of treating cognitive impairment
    Patent number: 7829087
    Abstract: Methods and compositions for suppressing amyloid-mediated inhibition of long-term potentiation (LTP) are provided.
    Type: Grant
    Filed: March 21, 2007
    Date of Patent: November 9, 2010
    Assignee: Elan Pharmaceuticals, Inc.
    Inventors: Sarah Wright, Irene Griswold-Prenner
  • Signaling intermediates in an in vitro model of Alzheimer's disease
    Patent number: 7674597
    Abstract: The invention provides a novel human protein, FISH adaptor protein, involved in amyloid ?-protein-mediated cell death. Also provided are methods for modulating amyloid ?-protein-mediated cell death using agents that interfere with the activity of FISH adaptor protein.
    Type: Grant
    Filed: August 1, 2005
    Date of Patent: March 9, 2010
    Assignee: Elan Pharmaceuticals, Inc.
    Inventors: Nikolay Malinin, Maile Skomp, Sarah Wright, Irene Griswold-Prenner
  • METHODS OF INHIBITING AMYLOID TOXICITY
    Publication number: 20090220505
    Abstract: The present invention features methods and compositions for inhibiting amyloidogenic protein toxicity, inhibiting formation of an amyloidogenic protein deposit and/or treating amyloidogenic diseases by administering a pharmaceutically effective amount of one or more agents that bind an integrin or an integrin subunit.
    Type: Application
    Filed: December 16, 2008
    Publication date: September 3, 2009
    Inventors: IRENE GRISWOLD-PRENNER, SARAH WRIGHT, THEODORE YEDNOCK, RUSSELL RYDEL
  • Methods of inhibiting amyloid toxicity
    Patent number: 7517525
    Abstract: The present invention features methods and compositions for inhibiting amyloidogenic protein toxicity, inhibiting formation of an amyloidogenic protein deposit and/or treating amyloidogenic diseases by administering a pharmaceutically effective amount of one or more agents that bind an integrin or an integrin subunit.
    Type: Grant
    Filed: July 9, 2002
    Date of Patent: April 14, 2009
    Assignee: Elan Pharmaceuticals, Inc.
    Inventors: Irene Griswald Prenner, Sarah Wright, Theodore Yednock, Russell Rydel
  • Methods of suppressing LTP inhibition
    Publication number: 20080193444
    Abstract: Methods and compositions for suppressing amyloid-mediated inhibition of long-term potentiation (LTP) are provided.
    Type: Application
    Filed: March 21, 2007
    Publication date: August 14, 2008
    Inventors: Sarah Wright, Irene Griswold-Prenner, Qinwen Wang, Igor Klyubin, Michael Rowan, Roger Anwyl
  • Signaling intermediates in an in vitro model of Alzheimer's disease
    Publication number: 20060159674
    Abstract: The invention provides a novel human protein, FISH adaptor protein, involved in amyloid ?-protein-mediated cell death. Also provided are methods for modulating amyloid ?-protein-mediated cell death using agents that interfere with the activity of FISH adaptor protein.
    Type: Application
    Filed: August 1, 2005
    Publication date: July 20, 2006
    Inventors: Nikolay Malinin, Maile Skomp, Sarah Wright, Irene Griswold-Prenner
  • Methods of inhibiting amyloid toxicity
    Publication number: 20030109435
    Abstract: The present invention features methods and compositions for inhibiting amyloidogenic protein toxicity, inhibiting formation of an amyloidogenic protein deposit and/or treating amyloidogenic diseases by administering a pharmaceutically effective amount of one or more agents that bind an integrin or an integrin subunit.
    Type: Application
    Filed: July 9, 2002
    Publication date: June 12, 2003
    Inventors: Irene Griswald Prenner, Sarah Wright, Theodore Yednock, Russell Rydel