Patents by Inventor Sarath Yandrapu

Sarath Yandrapu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LEDGF peptides and formulations thereof for treatment of degenerative disorders
    Patent number: 10221226
    Abstract: LEDGF peptides with anti-protein aggregation activity and methods of use are provided. The LEDGF peptides disclosed herein demonstrate an ability to treat degenerative diseases and diseases with various cellular stresses including oxidative stress and protein-aggregation stress. In addition, extended release formulations, including formulations suitable for ophthalmic administration are provided.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: March 5, 2019
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventors: Uday B. Kompella, Rinku Baid, Arun K. Upadhyay, Sarath Yandrapu
  • METHODS AND COMPOSITIONS FOR ENHANCED DRUG DELIVERY TO THE EYE AND EXTENDED DELIVERY FORMULATIONS
    Publication number: 20170151266
    Abstract: The present invention comprises compounds and compositions thereof for enhanced drug delivery. Pro-drug and double pro-drug derivatives of corticosteroids non-steroid anti-inflammatory drugs (NSAIDs), and ruboxistaurin for delivery to the eye are provided. The compounds and compositions are useful for treating various ocular diseases, including ocular diseases effecting the posterior segments of the eye. In addition, the present invention is directed to particle in particle carrier formulations for sustained release of therapeutic agents.
    Type: Application
    Filed: December 21, 2016
    Publication date: June 1, 2017
    Inventors: Uday B. Kompella, Ashish Thakur, Sarath Yandrapu
  • LEDGF PEPTIDES AND FORMULATIONS THEREOF FOR TREATMENT OF DEGENERATIVE DISORDERS
    Publication number: 20170129929
    Abstract: LEDGF peptides with anti-protein aggregation activity and methods of use are provided. The LEDGF peptides disclosed herein demonstrate an ability to treat degenerative diseases and diseases with various cellular stresses including oxidative stress and protein-aggregation stress. In addition, extended release formulations, including formulations suitable for ophthalmic administration are provided.
    Type: Application
    Filed: November 10, 2016
    Publication date: May 11, 2017
    Inventors: Uday B. KOMPELLA, Rinku BAID, Arun K. UPADHYAY, Sarath YANDRAPU
  • LEDGF peptides and formulations thereof for treatment of degenerative disorders
    Patent number: 9526760
    Abstract: LEDGF peptides with anti-protein aggregation activity and methods of use are provided. The LEDGF peptides disclosed herein demonstrate an ability to treat degenerative diseases and diseases with various cellular stresses including oxidative stress and protein-aggregation stress. In addition, extended release formulations, including formulations suitable for ophthalmic administration are provided.
    Type: Grant
    Filed: May 21, 2013
    Date of Patent: December 27, 2016
    Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
    Inventors: Uday B. Kompella, Rinku Baid, Arun K. Upadhyay, Sarath Yandrapu
  • LEDGF PEPTIDES AND FORMULATIONS THEREOF FOR TREATMENT OF DEGENERATIVE DISORDERS
    Publication number: 20150147404
    Abstract: LEDGF peptides with anti-protein aggregation activity and methods of use are provided. The LEDGF peptides disclosed herein demonstrate an ability to treat degenerative diseases and diseases with various cellular stresses including oxidative stress and protein-aggregation stress. In addition, extended release formulations, including formulations suitable for ophthalmic administration are provided.
    Type: Application
    Filed: May 21, 2013
    Publication date: May 28, 2015
    Applicant: The Regents of the University of Colorado, a body corporate
    Inventors: Uday B. Kompella, Rinku Baid, Arun K. Upadhyay, Sarath Yandrapu
  • Methods and Compositions for Enhanced Drug Delivery to the Eye and Extended Delivery Formulations
    Publication number: 20140309200
    Abstract: The present invention comprises compounds and compositions thereof for enhanced drug delivery. Pro-drug and double pro-drug derivatives of corticosteroids non-steroid anti-inflammatory drugs (NSAIDs), and ruboxistaurin for delivery to the eye are provided. The compounds and compositions are useful for treating various ocular diseases, including ocular diseases effecting the posterior segments of the eye. In addition, the present invention is directed to particle in particle carrier formulations for sustained release of therapeutic agents.
    Type: Application
    Filed: November 16, 2012
    Publication date: October 16, 2014
    Inventors: Uday B. Kompella, Sarath Yandrapu, Ashish Thakur