Patents by Inventor Saravanakumar Iyappan

Saravanakumar Iyappan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid encoding an isomerase, host cells containing the nucleic acid, and methods of making and using the host cells
    Patent number: 11421215
    Abstract: The present invention provides for a nucleic acid encoding an isomerase and uses of the isomerase for bioconversion of sugar substrates. The invention represents an advancement in the field of enzyme engineering and discloses a modified nucleic acid for achieving optimum expression of a protein having isomerase activity in a heterologous host. The invention also discloses vectors carrying the modified nucleic acid and recombinant host cells carrying the vectors. The invention also discloses the process for producing a recombinant host cell, process for production of the recombinant enzyme and the process for bioconversion of sugars into their respective isomers using the recombinant protein.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: August 23, 2022
    Assignee: PETIVA PRIVATE LIMITED
    Inventors: Saravanakumar Iyappan, Karthikeyan Venkata Narayanan, Banibrata Pandey
  • NUCLEIC ACID ENCODING AN ISOMERASE AND USES THEREOF
    Publication number: 20210024914
    Abstract: The present invention provides for a nucleic acid encoding an isomerase and uses of the isomerase for bioconversion of sugar substrates. The invention represents an advancement in the field of enzyme engineering and discloses a modified nucleic acid for achieving optimum expression of a protein having isomerase activity in a heterologous host. The invention also discloses vectors carrying the modified nucleic acid and recombinant host cells carrying the vectors. The invention also discloses the process for producing a recombinant host cell, process for production of the recombinant enzyme and the process for bioconversion of sugars into their respective isomers using the recombinant protein.
    Type: Application
    Filed: March 15, 2018
    Publication date: January 28, 2021
    Applicant: PETIVA PRIVATE LIMITED
    Inventors: Saravanakumar IYAPPAN, Karthikeyan VENKATA NARAYANAN, Banibrata PANDEY
  • Process for Preparing Non-Cariogenic, Sustained Energy Release Juice
    Publication number: 20190000116
    Abstract: The present invention provides a process for preparing non-cariogenic, sustained energy release juice. The process comprises contacting juice with an enzyme immobilized on Duolite at 30-50° C. for 1-5 h; wherein the enzyme is capable of converting cariogenic sugar to non-cariogenic sugar; and separating juice from the enzyme complex.
    Type: Application
    Filed: November 12, 2016
    Publication date: January 3, 2019
    Inventors: Banibrata Pandey, Rahul Raju Kanumuru, Saravanakumar Iyappan, Karthikeyan Venkata Narayanan, Humaira Parveen Sheikh
  • Polynucleotide for recombinant expression of sucrose isomerase
    Patent number: 9885030
    Abstract: The present invention is directed towards genetic modification of native gene encoding for sucrose isomerase and isomaltulose synthase to substantially increase the expression level of these enzymes and use of said enzymes in a process to produce rare disaccharides such as isomaltulose and trehalulose. Also disclosed in the present invention is expression constructs comprising the modified genes and a host cells to express the same.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: February 6, 2018
    Assignee: Petiva Private Limited
    Inventors: Samir Kumar Roy, Saravanakumar Iyappan, Saju Varghese, Aparna Devi Addala, Milky Agarwal, Kanumuru Rahul Raju, Banibrata Pandey
  • Method of Production of Rare Disaccharides
    Publication number: 20170267989
    Abstract: The present invention is directed towards genetic modification of native gene encoding for sucrose isomerase and isomaltulose synthase to substantially increase the expression level of these enzymes and use of said enzymes in a process to produce rare disaccharides such as isomaltulose and trehalulose. Also disclosed in the present invention is expression constructs comprising the modified genes and a host cells to express the same.
    Type: Application
    Filed: May 25, 2017
    Publication date: September 21, 2017
    Inventors: Samir Kumar Roy, Saravanakumar Iyappan, Saju Varghese, Aparna Devi Addala, Milky Agarwal, Kanumuru Rahul Raju, Banibrata Pandey
  • Method of production of monosaccharides
    Patent number: 9752170
    Abstract: The present invention is directed towards genetic modification of native gene encoding for D-tagatose 3-epimerase and rhamnose isomerase to substantially increase the expression level of these enzymes and use of the enzymes in a process to produce rare monosaccharides such as psicose and allose. Also disclosed in the present invention is expression constructs comprising the modified genes and a host cells to express the same.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: September 5, 2017
    Assignee: Petiva Private Limited
    Inventors: Saravanakumar Iyappan, Samir Kumar Roy, Saju Varghese, Aparna Devi Addala, Venkata Narayanan Karthikeyan, Kanumuru Rahul Raju, Banibrata Pandey
  • Polynucleotide for recombinant expression of isomaltulose synthase
    Patent number: 9695411
    Abstract: The present invention is directed towards genetic modification of native gene encoding for sucrose isomerase and isomaltulose synthase to substantially increase the expression level of these enzymes and use of said enzymes in a process to produce rare disaccharides such as isomaltulose and trehalulose. Also disclosed in the present invention is expression constructs comprising the modified genes and a host cells to express the same.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: July 4, 2017
    Assignee: Petiva Private Limited
    Inventors: Samir Kumar Roy, Saravanakumar Iyappan, Saju Varghese, Aparna Devi Addala, Milky Agarwal, Kanumuru Rahul Raju, Banibrata Pandey
  • Method of Production of Monosaccharides
    Publication number: 20150361473
    Abstract: The present invention is directed towards genetic modification of native gene encoding for D-tagatose 3-epimerase and rhamnose isomerase to substantially increase the expression level of these enzymes and use of said enzymes in a process to produce rare monosaccharides such as psicose and allose. Also disclosed in the present invention is expression constructs comprising the modified genes and a host cells to express the same.
    Type: Application
    Filed: April 17, 2013
    Publication date: December 17, 2015
    Inventors: Saravanakumar Iyappan, Samir Kumar Roy, Saju Varghese, Aparna Devi Addala, Venkata Narayanan Karthikeyan, Kanumuru Rahul Raju, Banibrata Pandey
  • Method of Production of Rare Disaccharides
    Publication number: 20150344865
    Abstract: The present invention is directed towards genetic modification of native gene encoding for sucrose isomerase and isomaltulose synthase to substantially increase the expression level of these enzymes and use of said enzymes in a process to produce rare disaccharides such as isomaltulose and trehalulose. Also disclosed in the present invention is expression constructs comprising the modified genes and a host cells to express the same.
    Type: Application
    Filed: April 17, 2013
    Publication date: December 3, 2015
    Inventors: Samir Kumar Roy, Saravanakumar Iyappan, Saju Varghese, Aparna Devi Addala, Milky Agarwal, Kanumuru Rahul Raju, Banibrata Pandey