Patents by Inventor Saravanamoorthy Rajendran

Saravanamoorthy Rajendran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180072769
    Abstract: Provided herein are methods of performing viral filtration on a fluid including a recombinant antibody, and the use of these methods in methods of manufacturing or producing the recombinant antibody.
    Type: Application
    Filed: March 23, 2016
    Publication date: March 15, 2018
    Applicant: ALEXION PHARMACEUTICALS, INC.
    Inventors: Bianca Olson, Saravanamoorthy Rajendran, Ryan Tedstone
  • Publication number: 20160176921
    Abstract: Provided herein are methods of purifying a recombinant protein and methods of manufacturing a recombinant protein product that include capturing a recombinant protein from a solution including the recombinant protein, following capturing, performing one or more unit operations on the solution, and after capturing and performing one or more unit operations, flowing the recombinant protein through a depth filter to provide a filtrate that includes purified recombinant protein and is substantially free of soluble protein aggregates.
    Type: Application
    Filed: December 22, 2015
    Publication date: June 23, 2016
    Inventors: Saravanamoorthy Rajendran, Luca Di Noto
  • Publication number: 20150361128
    Abstract: Provided are methods of using ion exchange based chromatography to control the levels of high mannose glycoforms in a glycoprotein sample, such as an antibody sample. The high mannose glycoforms can be removed from the sample or isolated and enriched. Also provided is a composition comprising a glycoprotein, such as an antibody, from which the high mannose glycoforms have been reduced or removed or isolated or enriched using an ion exchange based chromatography step.
    Type: Application
    Filed: December 18, 2013
    Publication date: December 17, 2015
    Inventors: Saravanamoorthy RAJENDRAN, Jihong WANG
  • Patent number: 8586345
    Abstract: The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.
    Type: Grant
    Filed: March 21, 2011
    Date of Patent: November 19, 2013
    Assignee: Virginia Commonwealth University Intellectual Property Foundation
    Inventors: David G. Simpson, Gary L. Bowlin, Gary E. Wnek, Peter J. Stevens, Marcus E. Carr, Jamil A. Matthews, Saravanamoorthy Rajendran
  • Publication number: 20110288026
    Abstract: The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.
    Type: Application
    Filed: March 21, 2011
    Publication date: November 24, 2011
    Inventors: David G. Simpson, Gary L. Bowlin, Gary E. Wnek, Peter J. Stevens, Marcus E. Carr, Jamil A. Matthews, Saravanamoorthy Rajendran
  • Patent number: 7615373
    Abstract: The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.
    Type: Grant
    Filed: May 28, 2003
    Date of Patent: November 10, 2009
    Assignees: Virginia Commonwealth University Intellectual Property Foundation, Organogenesis, Inc.
    Inventors: David G. Simpson, Gary L. Bowlin, Gary E. Wnek, Peter J. Stevens, Marcus E. Carr, Jamil A. Matthews, Saravanamoorthy Rajendran
  • Publication number: 20080038352
    Abstract: The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.
    Type: Application
    Filed: August 21, 2007
    Publication date: February 14, 2008
    Applicants: Virginia Commonwealth University Intellectual Property Foundation, Nanomatrix, Inc.
    Inventors: David Simpson, Gary Bowlin, Gary Wnek, Peter Stevens, Marcus Carr, Jamil Matthews, Saravanamoorthy Rajendran
  • Publication number: 20060094651
    Abstract: The present invention provides improved formulations comprising FGF-20, its fragments, derivatives, variants, homologs, analogs, or a combination thereof, and improved methods for production.
    Type: Application
    Filed: November 3, 2004
    Publication date: May 4, 2006
    Inventors: Cyrus Karkaria, Tracy Chen, Rajeev Chillakuru, Gan Wei, Saravanamoorthy Rajendran
  • Publication number: 20040037813
    Abstract: The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.
    Type: Application
    Filed: May 28, 2003
    Publication date: February 26, 2004
    Inventors: David G. Simpson, Gary L. Bowlin, Gary E. Wnek, Peter J. Stevens, Marcus E. Carr, Jamil A. Matthews, Saravanamoorthy Rajendran
  • Publication number: 20020090725
    Abstract: The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.
    Type: Application
    Filed: November 16, 2001
    Publication date: July 11, 2002
    Inventors: David G. Simpson, Gary L. Bowlin, Gary E. Wnek, Peter J. Stevens, Marcus E. Carr, Jamil A. Matthews, Saravanamoorthy Rajendran