Patents by Inventor Sari S. Hannila

Sari S. Hannila has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protein transduction domains derived from secretory leukocyte protease inhibitor
    Patent number: 8598315
    Abstract: This invention relates to novel protein transduction domains (PTDs) derived from secretory leukocyte protease inhibitor (SLPI). SLPI-derived PTDs are able to deliver cargo moieties in vivo and in vitro into the cytoplasm and nucleus of a host cell. The invention also relates to a transduction complex comprising one or more SLPI-derived PTDs linked or fused to one or more cargo moieties, which may comprise, for example, proteins, nucleic acids, lipids, carbohydrates, small molecules and other chemical compounds. The invention also relates to the manufacture of SLPI-derived PTDs, complexes comprising them; compositions comprising SLPI-derived PTDs or complexes; and utilization of SLPI-derived PTDs or complexes comprising them for therapeutic, diagnostic and research methods involving delivery of heterologous molecules across cellular membranes, and especially, across nuclear membranes.
    Type: Grant
    Filed: October 2, 2008
    Date of Patent: December 3, 2013
    Assignee: Research Foundation of City University of New York
    Inventors: Marie T. Filbin, Sari S. Hannila
  • Stimulation of neuron regeneration by secretory leukocyte protease inhibitor
    Patent number: 8367615
    Abstract: The present invention provides methods for stimulating neuronal survival, growth and regeneration by administering SLPIs to animals, such as humans. These methods can be used to treat a variety of neurological conditions such as neural injuries and degenerative diseases in subjects in need thereof.
    Type: Grant
    Filed: March 30, 2007
    Date of Patent: February 5, 2013
    Assignee: Research Foundation of City University of New York
    Inventors: Marie T. Filbin, Sari S. Hannila
  • STIMULATION OF NEURON REGENERATION BY SECRETORY LEUKOCYTE PROTEASE INHIBITOR
    Publication number: 20100256065
    Abstract: The present invention provides methods for stimulating neuronal survival, growth and regeneration by administering SLPIs to animals, such as humans. These methods can be used to treat a variety of neurological conditions such as neural injuries and degenerative diseases in subjects in need thereof.
    Type: Application
    Filed: March 30, 2007
    Publication date: October 7, 2010
    Applicant: Research Foundation of City University of New York
    Inventors: Marie T. Filbin, Sari S. Hannila