Patents by Inventor Sarina Striem

Sarina Striem has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIPOPHILIC DIESTERS OF CHELATING AGENT FOR INHIBITION OF ENZYME ACTIVITY
    Publication number: 20110105607
    Abstract: The present invention relates to the use of lipophilic diesters of the chelating agent 1,2-bis(2 aminophenoxy)ethane-N,N,N?,N?-tetraacetic acid (BAPTA) for inhibition of proteolytic activities of certain metalloproteinases, calpain and TACE The invention further relates to methods for preventing, treating or managing TACE-related diseases or disorders in mammals comprising administering to a mammal in need thereof, a pharmaceutical composition comprising a therapeutically effective amount of said lipophilic diesters of the chelating agent BAPTA.
    Type: Application
    Filed: August 12, 2010
    Publication date: May 5, 2011
    Applicant: D-PHARM Ltd.
    Inventors: Sarina STRIEM, Jonathan Eduard Friedman, Dalia Reznitsky-Cohen, Alexander Kozak
  • Lipophilic diesters of chelating agent for inhibition of enzyme activity
    Patent number: 7799831
    Abstract: The present invention relates to the use of lipophilic diesters of the chelating agent 1,2-bis(2 aminophenoxy)ethane-N,N,N?,N?-tetraacetic acid (BAPTA) for inhibition of proteolytic activities of certain metalloproteinases and of calpain. The invention further relates to methods for preventing, treating or managing MMP-related and calpain-related diseases or disorders in mammals comprising administering to a mammal in need thereof, a pharmaceutical composition comprising a therapeutically effective amount of said lipophilic diesters of the chelating agent BAPTA.
    Type: Grant
    Filed: March 16, 2003
    Date of Patent: September 21, 2010
    Assignee: D-Pharm Ltd.
    Inventors: Sarina Striem, Jonathan Eduard Friedman, Dalia Reznitsky-Cohen, Alexander Kozak
  • Lipophilic diesters of chelating agent for inhibition of enzyme activity
    Publication number: 20060167092
    Abstract: The present invention relates to the use of lipophilic diesters of the chelating agent 1,2-bis(2 aminophenoxy)ethane-N,N,N?,N?-tetraacetic acid (BAPTA) for inhibition of proteolytic activities of certain metalloproteinases and of calpain. The invention further relates to methods for preventing, treating or managing MMP-related and calpain-related diseases or disorders in mammals comprising administering to a mammal in need thereof, a pharmaceutical composition comprising a therapeutically effective amount of said lipophilic diesters of the chelating agent BAPTA.
    Type: Application
    Filed: March 16, 2003
    Publication date: July 27, 2006
    Applicant: D-Pharm Ltd
    Inventors: Sarina Striem, Jonathan Friedman, Dalia Reznitsky-Cohen, Alexander Kozak