Patents by Inventor Sarnie R. Jaffrey

Sarnie R. Jaffrey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of enhancing translation ability and stability of RNA molecules, treatments, and kits
    Patent number: 10907165
    Abstract: The present invention relates to methods of enhancing the translation ability and stability of an RNA molecule. The methods involve providing a cell-free composition comprising an RNA molecule to be translated, where the RNA molecule lacks an N6,2?O-dimethyladenosine (“m6Am”) residue. Also disclosed are methods of making RNA molecules and treatment methods using an RNA molecule comprising a 7-methylguanosine (“m7G”), a 5? triphosphate linker (“-ppp-”), and an N6,2?-0-dimethyladenosine (m6Am).
    Type: Grant
    Filed: October 31, 2017
    Date of Patent: February 2, 2021
    Assignee: CORNELL UNIVERSITY
    Inventors: Sarnie R. Jaffrey, Jan Mauer