Abstract: An improved belt scraper assembly for belt conveyors includes one or more blade assemblies and one or more hinge assemblies mounted on either side of a supporting flexible member for facilitating twin blade cleaning. The one or blade assemblies are operatively connected to the hinge assembly, which is adapted to ensure limited rotational motion of said blade assembly.

Abstract: An improved belt scraper assembly for belt conveyors includes one or more blade assemblies and one or more hinge assemblies mounted on either side of a supporting flexible member for facilitating twin blade cleaning. The one or blade assemblies are operatively connected to the hinge assembly, which is adapted to ensure limited rotational motion of said blade assembly.

Abstract: A belt scraper mounting for belt conveyors with a conveyor frame/stringer includes a scraper blade module assembly and a scraper fixing mount. The scraper fixing mount holds the blade module assembly with the conveyor frame/stringer on both sides of the scraper blade module assembly and functions in an auto adjusting mode.

Abstract: An improved bet scraper mounting for belt conveyors having conveyor frame/stringer, comprising: scraper blade module assembly (3) and a means (1,2,4) for holding said bade module assembly with said conveyor frame/stringer on both sides of said belt scraper, said means being adapted to function in an auto adjusting mode.

Abstract: The invention relates to the chemical synthesis of oligonucleotides and to chemical entities useful in such synthesis. More particularly, the invention relates to sulfurization of the internucleotide linkages of oligonucleotides. The invention provides a process to synthesize new sulfur transfer reagents and a process for their use in sulfurizing oligonucleotides. The sulfur transfer reagents according to the invention are inexpensive to make, stable in storage and in solution, and highly efficient in sulfurization.

Abstract: In our research, 3-phenyl-1,2,4-dithiazoline-5-one is found to be a potential sulfur-transfer reagent. The efficiency and optimization of this new sulfur-transfer reagent was investigated by solid-phase syntheses of dinucleotide phosphorothioate and 25 mer oligonucleotide phosphorothioates at 1 &mgr;mol and 200 &mgr;mol scales. The results show that 3-phenyl-1,2,4-dithiazoline-5-one is a highly efficient sulfurizing reagent, and greater than 99.8% sulfur transfer efficiency can be achieved. In contrast to EDITH or Beaucage reagent, this novel sulfur-transfer reagent is highly stable in storage and in solution, highly soluble in CH3CN solvent, and can be synthesized at a low cost because of the single step reaction. Due to these advantages, 3-phenyl-1,2,4-dithiazoline-5-one can be considered as a better alternative to EDITH or Beaucage reagent, especially in large-scale preparation of oligonucleotide phosphorothioates.

Abstract: This invention is directed to N (amino)-protected-2'-O-methyl (methoxy)-5'-dimethoxytrityl (dimethoxytrityl) ribonucleosides (Group I compounds) and to N-protected-2'-O-methyl-5'-dimethoxytrityl-3'-ribonucleoside cyanoethyl N,N-diisopropyl phosphoramidites (Group II compounds). This invention is further directed to the processes involved in producing these compounds. The purification processes produce products in Group I with purity in excess of 99.50% and up to 99.8%. The purity of the products in Group II ranges in excess of 99.8% and up to 99.9%.