Patents by Inventor Saroop Singh Matharu

Saroop Singh Matharu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing alkyl esters of 4-(5-(bis(2-hydroxyethyl)amino-1-methyl-1H-benzo[D]imidazol-2-yl)butyric acid
    Patent number: 10252999
    Abstract: An alkyl ester of 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butyric acid, such as ethyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate, is obtained by reacting an alkyl ester of 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butyric acid with 2-hydroxyacetaldehyde under reducing conditions.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: April 9, 2019
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Xing Fu, Saroop Singh Matharu
  • PROCESS FOR PREPARING ALKYL ESTERS OF 4-(5-(BIS(2-HYDROXYETHYL)AMINO-1-METHYL-1H-BENZO[D]IMIDAZOL-2-YL)BUTYRIC ACID
    Publication number: 20180105499
    Abstract: An alkyl ester of 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butyric acid, such as ethyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate, is obtained by reacting an alkyl ester of 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butyric acid with 2-hydroxyacetaldehyde under reducing conditions.
    Type: Application
    Filed: December 18, 2017
    Publication date: April 19, 2018
    Inventors: Xing FU, Saroop Singh MATHARU
  • Methods for making polymorphs of bromfenac sodium and bromfenac sodium formulations
    Patent number: 9914697
    Abstract: Different polymorphs of bromfenac sodium may be prepared and interconverted using crystallization/recrystallization, drying and/or hydration techniques.
    Type: Grant
    Filed: June 12, 2015
    Date of Patent: March 13, 2018
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Saroop Singh Matharu, Gurijala Venu Reddy, James J. Mencel, Xiaoyong Sun
  • Processes for making hydrocodone, hydromorphone and their derivatives
    Patent number: 9657027
    Abstract: Improved processes for making hydrocodone and hydromorphone as well as their 8,14-dihydrothebaine and 8,14-dihydrooripavine derivatives and salts are disclosed.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: May 23, 2017
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Saroop Singh Matharu, Ewart Grant, Brian W. Heinrich
  • Processes for making hydrocodone, hydromorphone and their derivatives
    Patent number: 9657028
    Abstract: Improved processes for making hydrocodone and hydromorphone as well as their 8,14-dihydrothebaine and 8,14-dihydrooripavine derivatives and salts are disclosed.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: May 23, 2017
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Saroop Singh Matharu, Ewart Grant, Brian W. Heinrich
  • PROCESSES FOR MAKING HYDROCODONE, HYDROMORPHONE AND THEIR DERIVATIVES
    Publication number: 20160137655
    Abstract: Improved processes for making hydrocodone and hydromorphone as well as their 8,14-dihydrothebaine and 8,14-dihydrooripavine derivatives and salts are disclosed.
    Type: Application
    Filed: January 22, 2016
    Publication date: May 19, 2016
    Applicant: Johnson Matthey Public Limited Company
    Inventors: Saroop Singh MATHARU, Ewart GRANT, Brian W. HEINRICH
  • PROCESSES FOR MAKING HYDROCODONE, HYDROMORPHONE AND THEIR DERIVATIVES
    Publication number: 20160137656
    Abstract: Improved processes for making hydrocodone and hydromorphone as well as their 8,14-dihydrothebaine and 8,14-dihydrooripavine derivatives and salts are disclosed.
    Type: Application
    Filed: January 22, 2016
    Publication date: May 19, 2016
    Applicant: Johnson Matthey Public Limited Company
    Inventors: Saroop Singh MATHARU, Ewart GRANT, Brian W. HEINRICH
  • Processes for making hydrocodone, hydromorphone and their derivatives
    Patent number: 9273060
    Abstract: Improved processes for making hydrocodone and hydromorphone as well as their 8,14-dihydrothebaine and 8,14-dihydrooripavine derivatives and salts are disclosed.
    Type: Grant
    Filed: March 5, 2014
    Date of Patent: March 1, 2016
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Saroop Singh Matharu, Ewart Grant, Brian W. Heinrich
  • Processes for Making Opioids Including 14-Hydroxycodeinone and 14-hydroxymorphinone
    Publication number: 20160052932
    Abstract: Improved processes for making opioid products having low impurity levels including making 14-hydroxycodeinone and 14-hydroxymorphinone from thebaine and oripavine, respectively.
    Type: Application
    Filed: August 25, 2014
    Publication date: February 25, 2016
    Inventors: Saroop Singh MATHARU, Brian W. HEINRICH, Ewart GRANT, Hongzhi ZHANG
  • Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
    Patent number: 9216947
    Abstract: Different polymorphs of bromfenac sodium may be prepared and interconverted using crystallization/recrystallization, drying and/or hydration techniques.
    Type: Grant
    Filed: June 24, 2013
    Date of Patent: December 22, 2015
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Saroop Singh Matharu, Gurijala Venu Reddy, James J. Mencel, Xiaoyong Sun
  • METHODS FOR MAKING POLYMORPHS OF BROMFENAC SODIUM AND BROMFENAC SODIUM FORMULATIONS
    Publication number: 20150274641
    Abstract: Different polymorphs of bromfenac sodium may be prepared and interconverted using crystallization/recrystallization, drying and/or hydration techniques.
    Type: Application
    Filed: June 12, 2015
    Publication date: October 1, 2015
    Inventors: Saroop Singh MATHARU, Gurijala Venu REDDY, James J. MENCEL, Xiaoyong Sun
  • PROCESSES FOR MAKING HYDROCODONE, HYDROMORPHONE AND THEIR DERIVATIVES
    Publication number: 20150252052
    Abstract: Improved processes for making hydrocodone and hydromorphone as well as their 8,14-dihydrothebaine and 8,14-dihydrooripavine derivatives and salts are disclosed.
    Type: Application
    Filed: March 5, 2014
    Publication date: September 10, 2015
    Applicant: JOHNSON MATTHEY PUBLIC LIMITED COMPANY
    Inventors: Saroop Singh MATHARU, Ewart GRANT, Brian W. HEINRICH
  • Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
    Patent number: 9061968
    Abstract: Different polymorphs of bromfenac sodium may be prepared and interconverted using crystallization/recrystallization, drying and/or hydration techniques.
    Type: Grant
    Filed: September 13, 2013
    Date of Patent: June 23, 2015
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Saroop Singh Matharu, Gurijala Venu Reddy, James J. Mencel, Xiaoyong Sun
  • Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
    Patent number: 9045388
    Abstract: Different polymorphs of bromfenac sodium may be prepared and interconverted using crystallization/recrystallization, drying and/or hydration techniques.
    Type: Grant
    Filed: September 13, 2013
    Date of Patent: June 2, 2015
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Saroop Singh Matharu, Gurijala Venu Reddy, James J. Mencel, Xiaoyong Sun
  • PROCESS FOR PREPARING ALKYL ESTERS OF 4-(5-(BIS(2-HYDROXYETHYL)AMINO)-1-METHYL-1H-BENZO[D]IMIDAZOL-2-YL)BUTYRIC ACID
    Publication number: 20140275567
    Abstract: An alkyl ester of 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butyric acid, such as ethyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate, is obtained by reacting an alkyl ester of 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butyric acid with 2-hydroxyacetaldehyde under reducing conditions.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Applicant: JOHNSON MATTHEY PLC
    Inventors: Xing Fu, Saroop Singh Matharu
  • POLYMORPHS OF BROMFENAC SODIUM AND METHODS FOR PREPARING BROMFENAC SODIUM POLYMORPHS
    Publication number: 20140018428
    Abstract: Different polymorphs of bromfenac sodium may be prepared and interconverted using crystallization/recrystallization, drying and/or hydration techniques.
    Type: Application
    Filed: September 13, 2013
    Publication date: January 16, 2014
    Applicant: Johnson Matthey Public Limited Company
    Inventors: Saroop Singh Matharu, Gurijala Venu Reddy, James J. Mencel, Xiaoyong Sun
  • POLYMORPHS OF BROMFENAC SODIUM AND METHODS FOR PREPARING BROMFENAC SODIUM POLYMORPHS
    Publication number: 20140011880
    Abstract: Different polymorphs of bromfenac sodium may be prepared and interconverted using crystallization/recrystallization, drying and/or hydration techniques.
    Type: Application
    Filed: September 13, 2013
    Publication date: January 9, 2014
    Applicant: Johnson Matthey Public Limited Company
    Inventors: Saroop Singh Matharu, Gurijala Venu Reddy, James J. Mencel, Xiaoyong Sun
  • POLYMORPHS OF BROMFENAC SODIUM AND METHODS FOR PREPARING BROMFENAC SODIUM POLYMORPHS
    Publication number: 20130289120
    Abstract: Different polymorphs of bromfenac sodium may be prepared and interconverted using crystallization/recrystallization, drying and/or hydration techniques.
    Type: Application
    Filed: June 24, 2013
    Publication date: October 31, 2013
    Inventors: Saroop Singh Matharu, Gurijala Venu Reddy, James J. Mencel, Xiaoyong Sun
  • Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
    Patent number: 8481780
    Abstract: Different polymorphs of bromfenac sodium may be prepared and interconverted using crystallization/recrystallization, drying and/or hydration techniques.
    Type: Grant
    Filed: September 25, 2012
    Date of Patent: July 9, 2013
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Saroop Singh Matharu, Gurijala Venu Reddy, James J. Mencel, Xiaoyong Sun
  • POLYMORPHS OF BROMFENAC SODIUM AND METHODS FOR PREPARING BROMFENAC SODIUM POLYMORPHS
    Publication number: 20130023588
    Abstract: Different polymorphs of bromfenac sodium may be prepared and interconverted using crystallization/recrystallization, drying and/or hydration techniques.
    Type: Application
    Filed: September 25, 2012
    Publication date: January 24, 2013
    Inventors: Saroop Singh Matharu, Gurijala Venu Reddy, James J. Mencel, Xiaoyong Sun