Patents by Inventor Sarvaji Chakravarty

Sarvaji Chakravarty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of malignant gliomas with TGF-beta inhibitors
    Publication number: 20050245508
    Abstract: The invention concerns methods of treating malignant gliomas, by administering inhibitors of TGF-? the TGF-? signaling pathway, including molecules preferably binding to the type I TGF-? receptor (TGF?-R1). Preferably, the inhibitors are non-peptide small molecules, including quinazoline derivatives. The invention also concerns methods for reversing the TGF-?-mediated effect on glioma cells to make them less refractile to signaling and other immune cells, comprising contacting a glioma cell or tissue in vivo or in vitro, with an inhibitor of TGF-?.
    Type: Application
    Filed: December 22, 2004
    Publication date: November 3, 2005
    Applicant: SCIOS, Inc.
    Inventors: Michael Weller, Sundeep Dugar, Linda Higgins, David Liu, George Schreiner, Sarvaji Chakravarty