Patents by Inventor Sarvajit Chakravarty

Sarvajit Chakravarty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ATF6 INHIBITORS AND USES THEREOF
    Publication number: 20240124434
    Abstract: Compounds as inhibitors of Activating Transcription Factor 6 (ATF6) are provided. The compounds may find use as therapeutic agents for the treatment of diseases or disorders mediated by ATF6 and may find particular use in the treatment of viral infections, neurodegenerative diseases, vascular diseases, or cancer.
    Type: Application
    Filed: May 26, 2023
    Publication date: April 18, 2024
    Inventors: Jennifer ALFARO, Sebastian BELMAR, Gonzalo Esteban NÚÑEZ VASQUEZ, Brahmam PUJALA, Balaji Dashrath SATHE, Pooja THAKRAL, Rajesh Kumar PATIDAR, Sebastian BERNALES, Sarvajit CHAKRAVARTY
  • Anti-cancer nuclear hormone receptor-targeting compounds
    Patent number: 11826430
    Abstract: The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.
    Type: Grant
    Filed: May 13, 2020
    Date of Patent: November 28, 2023
    Assignee: NUVATION BIO INC.
    Inventors: David Hung, Son Minh Pham, Sarvajit Chakravarty, Jiyun Chen, Jayakanth Kankanala, Jeremy D. Pettigrew, Anup Barde, Anjan Kumar Nayak
  • HETEROCYCLIC COMPOUNDS AS BET INHIBITORS
    Publication number: 20230339964
    Abstract: Novel bromodomain and extraterminal domain (BET) inhibitors and to therapeutic methods of treating conditions and diseases using these novel BET inhibitors are provided.
    Type: Application
    Filed: January 9, 2023
    Publication date: October 26, 2023
    Inventors: Son Minh PHAM, Sarvajit Chakravarty, Jayakanth Kankanaka, Jiyun Chen, Chris P. Miller, Jeremy D. Pettigrew, Anjan Kumar Nayak, Anup Barde
  • Compounds and methods of use
    Patent number: 11702401
    Abstract: This disclosure provides compounds and compositions and methods of using those compounds and compositions to treat diseases and disorders associated with excessive transforming growth factor-beta (TGF?) activity. This disclosure also provides methods of using the compounds in combination with one or more cancer immunotherapies.
    Type: Grant
    Filed: May 22, 2021
    Date of Patent: July 18, 2023
    Assignee: Medivation Technologies LLC
    Inventors: Roopa Rai, Sarvajit Chakravarty, Brahmam Pujala, Bharat Uttam Shinde, Anjan Kumar Nayak, Anil Kumar Agarwal, Sreekanth A. Ramachandran, Son Minh Pham
  • ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS
    Publication number: 20230122310
    Abstract: The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.
    Type: Application
    Filed: November 22, 2022
    Publication date: April 20, 2023
    Inventors: David Hung, Son Minh Pham, Sarvajit Chakravarty, Jiyun Chen, Jayakanth Kankanala, Anup Barde, Anjan Kumar Nayak
  • SUBSTITUTED PYRAZOLO[3,4-d]PYRIMIDINES AS WEE1 INHIBITORS
    Publication number: 20230118115
    Abstract: This invention provides for substituted pyrazolo[3,4-d]pyrimidine compounds of the Formula (I): as Wee1 inhibitors. The substituted pyrazolo[3,4-d]pyrimidine compounds may find use as therapeutic agents for the treatment of diseases. The substituted pyrazolo[3,4-d]pyrimidine compounds may also find particular use in oncology.
    Type: Application
    Filed: May 12, 2022
    Publication date: April 20, 2023
    Inventors: Sarvajit CHAKRAVARTY, Son Minh PHAM, Jayakanth KANKANALA, Brahmam PUJALA, Sanjeev SONI, Puja JAISWAL, Deepak PALVE, Varun KUMAR
  • HETEROCYCLIC COMPOUNDS AND USES THEREOF
    Publication number: 20230109104
    Abstract: Heterocyclic compounds as Wee1 inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.
    Type: Application
    Filed: April 8, 2022
    Publication date: April 6, 2023
    Inventors: Sarvajit CHAKRAVARTY, Son Minh PHAM, Jayakanth KANKANALA, Anil Kumar AGARWAL, Brahmam PUJALA, Sanjeev SONI, Satish K. ARYA, Deepak PALVE, Ashu GUPTA, Varun KUMAR
  • MODULATORS OF INTEGRATED STRESS RESPONSE PATHWAY
    Publication number: 20230083885
    Abstract: The present disclosure relates generally to therapeutic agents that may be useful as modulators of Integrated Stress Response (ISR) pathway.
    Type: Application
    Filed: April 1, 2022
    Publication date: March 16, 2023
    Inventors: Gonzalo Andrés URETA DÍAZ, Brahmam PUJALA, Dayanand PANPATIL, Sebastian BERNALES, Sarvajit CHAKRAVARTY
  • HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS
    Publication number: 20230062022
    Abstract: Heterocyclic compounds as CDK4 or CDK6 or other CDK inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.
    Type: Application
    Filed: October 1, 2021
    Publication date: March 2, 2023
    Inventors: Son Minh PHAM, Sarvajit Chakravarty, Jayakanth Kankanala, Brahmam Pujala, Amit Shete, Bhawana Bhatt, Anil Kumar Agarwal, Sanjeev Soni, Jiyun Chen
  • Heterocyclic compounds as BET inhibitors
    Patent number: 11584756
    Abstract: Novel bromodomain and extraterminal domain (BET) inhibitors and to therapeutic methods of treating conditions and diseases using these novel BET inhibitors are provided.
    Type: Grant
    Filed: July 1, 2020
    Date of Patent: February 21, 2023
    Assignee: NUVATION BIO INC.
    Inventors: Son Minh Pham, Sarvajit Chakravarty, Jayakanth Kankanala, Jiyun Chen, Chris P. Miller, Jeremy D. Pettigrew, Anjan Kumar Nayak, Anup Barde
  • INHIBITORS OF INTEGRATED STRESS RESPONSE PATHWAY
    Publication number: 20230047589
    Abstract: The present disclosure relates generally to therapeutic agents that may be useful as inhibitors of Integrated Stress Response (ISR) pathway.
    Type: Application
    Filed: August 10, 2021
    Publication date: February 16, 2023
    Inventors: Sebastian BERNALES, Luz Marina DELGADO OYARZO, Gonzalo Esteban NÚÑEZ VASQUEZ, Gonzalo Andrés URETA DÍAZ, Brahmam PUJALA, Dayanand PANPATIL, Bhawana BHATT, Sarvajit CHAKRAVARTY
  • MODULATORS OF INTEGRATED STRESS RESPONSE PATHWAY
    Publication number: 20230042881
    Abstract: The present disclosure relates generally to therapeutic agents that may be useful as modulators of Integrated Stress Response (ISR) pathway.
    Type: Application
    Filed: June 3, 2022
    Publication date: February 9, 2023
    Inventors: Gonzalo Andrés URETA DÍAZ, Brahmam PUJALA, Dayanand PANPATIL, Sebastian BERNALES, Sarvajit CHAKRAVARTY
  • HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20230023009
    Abstract: The present disclosure relates to inhibitors of one or more isoforms of RAS, such as inhibitors of one or more of KRAS, HRAS and NRAS, or mutants thereof, such as G12D, G12V, G13D or G12C mutants thereof. Therapeutic methods of treating conditions and diseases using these inhibitors are also provided.
    Type: Application
    Filed: June 4, 2021
    Publication date: January 26, 2023
    Inventors: Jayakanth KANKANALA, Jeremy D. PETTIGREW, Son Minh PHAM, Sarvajit CHAKRAVARTY, Jiyun CHEN
  • HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20230026856
    Abstract: The present disclosure relates to inhibitors of one or more isoforms of RAS, such as inhibitors of one or more of KRAS, HRAS and NRAS, or mutants thereof, such as G12D, G12V, G13D or G12C mutants thereof. Therapeutic methods of treating conditions and diseases using these inhibitors are also provided.
    Type: Application
    Filed: June 4, 2021
    Publication date: January 26, 2023
    Inventors: Jayakanth KANKANALA, Jeremy D. PETTIGREW, Son Minh PHAM, Sarvajit CHAKRAVARTY, Jiyun CHEN
  • COMPOUNDS AND USES THEREOF
    Publication number: 20230002356
    Abstract: Provided herein are compounds, such as compounds for use in treating cancer. Also provided are methods of treating cancer, including treatment resistant cancer or cancer associated with a hypoxic tumor.
    Type: Application
    Filed: September 17, 2020
    Publication date: January 5, 2023
    Applicant: Pano Therapeutics, Inc.
    Inventors: Francesca FIENI, Son Minh PHAM, Sarvajit CHAKRAVARTY
  • HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS
    Publication number: 20220347187
    Abstract: Heterocyclic compounds as CDK4 or CDK6 or other CDK inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.
    Type: Application
    Filed: August 13, 2020
    Publication date: November 3, 2022
    Inventors: Sarvajit CHAKRAVARTY, Son Minh PHAM, Jayakanth KANKANALA, Jiyun CHEN, Brahmam PUJALA, Bhawana BHATT, Mukesh GANGAR, Amit S. SHETE
  • Derivatives of piperlongumine and uses thereof
    Patent number: 11485725
    Abstract: The present invention relates to a group of 1-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]-2,3-dihydropyridin-6-one (piperlongumine) derivatives, analogs and pharmaceutically acceptable salts thereof. The present invention also relates to processes for preparing the same; a pharmaceutical composition and formulation containing a derivative of piperlongumine; and use of the derivatives and analogs for treating cancer.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: November 1, 2022
    Assignee: Auransa Inc.
    Inventors: Andrew Asher Protter, Michael John Green, Hak Jin Chang, Son Minh Pham, Sarvajit Chakravarty, Gregory R. Luedtke, Pek Yee Lum
  • HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS
    Publication number: 20220281859
    Abstract: Heterocyclic compounds as CDK4 or CDK6 or other CDK inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.
    Type: Application
    Filed: August 13, 2020
    Publication date: September 8, 2022
    Applicant: Nuvation Bio Inc.
    Inventors: Sarvajit CHAKRAVARTY, Son Minh PHAM, Jayakanth KANKANALA, Jiyun CHEN, Brahmam PUJALA, Bhawana BHATT, Mukesh GANGAR, Amit S. SHETE
  • HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS
    Publication number: 20220273659
    Abstract: Heterocyclic compounds as CDK4 or CDK6 or other CDK inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.
    Type: Application
    Filed: July 1, 2020
    Publication date: September 1, 2022
    Inventors: Son Minh PHAM, Sarvajit CHAKRAVARTY, Jayakanth KANKANALA, Brahmam PUJALA, Amit SHETE, Mukesh GANGAR, Bhawana BHATT, Chris P. MILLER, Jeremy D. PETTIGREW
  • 1,8-NAPHTHYRIDINONE COMPOUNDS AND USES THEREOF
    Publication number: 20220220111
    Abstract: 1,8-naphthyridinone compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.
    Type: Application
    Filed: December 13, 2021
    Publication date: July 14, 2022
    Inventors: Son Minh Phan, Jiyun Chen, Amantullah Ansari, Pradeep S. Jadhavar, Varshavekumar S. Patil, Farha Khan, Sreekanth A. Ramachandran, Anil Kumar Agarwal, Sarvajit Chakravarty