Patents by Inventor Sasan AMINI

Sasan AMINI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210047635
    Abstract: Presented herein are methods and compositions for tagmentation of nucleic acids. The methods are useful for generating tagged DNA fragments that are qualitatively and quantitatively representative of the target nucleic acids in the sample from which they are generated.
    Type: Application
    Filed: September 2, 2020
    Publication date: February 18, 2021
    Inventors: Christian Gloeckner, Amirali Kia, Molly He, Trina Faye Osothprarop, Frank J. Steemers, Kevin L. Gunderson, Sasan Amini, Jerome Jendrisak
  • Patent number: 10815478
    Abstract: Presented herein are methods and compositions for tagmentation of nucleic acids. The methods are useful for generating tagged DNA fragments that are qualitatively and quantitatively representative of the target nucleic acids in the sample from which they are generated.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: October 27, 2020
    Assignee: Illumina, Inc.
    Inventors: Christian Gloeckner, Amirali Kia, Molly He, Trina Faye Osothprarop, Frank J. Steemers, Kevin L. Gunderson, Sasan Amini, Jerome Jendrisak
  • Publication number: 20200265918
    Abstract: The present invention relates to a combination of experimental and computational workflows that allow characterization of specific molecular mechanisms by which the microbiome contribute to skin health and skin age.
    Type: Application
    Filed: April 28, 2020
    Publication date: August 20, 2020
    Inventors: Dana HOSSEINI, Sasan AMINI, Eveie SCHWARTZ
  • Publication number: 20200251181
    Abstract: Provided herein are automated apparatus for the identification of microorganisms in various samples. The disclosure solves existing challenges encountered in identifying and distinguishing various types of microorganisms, including viruses and bacteria in a timely, efficient, and automated manner by sequencing.
    Type: Application
    Filed: April 22, 2020
    Publication date: August 6, 2020
    Inventors: Sasan AMINI, Ramin KHAKSAR, Michael TAYLOR, Shadi SHOKRALLA, Christopher HANEY, Pavan VAIDYANATHAN, Stephanie POLLARD, Adam ALLRED, Sima MORTAZAVI, David TRAN, Hossein NAMAZI, Julius BARSI
  • Publication number: 20200224268
    Abstract: Embodiments disclosed herein provide methods for constructing a DNA profile comprising: providing a nucleic acid sample, amplifying the nucleic acid sample with a plurality of primers that specifically hybridize to at least one target sequence comprising a SNP and at least one target sequence comprising a tandem repeat, and determining the genotypes of the at least one SNP and at least one tandem repeat in the amplification products, thereby constructing the DNA profile of the nucleic acid sample. Embodiments disclosed herein further provide a plurality of primers that specifically hybridize to at least one short target sequence and at least one long target sequence in a nucleic acid sample, wherein amplifying the nucleic acid sample using the plurality of primers in a single reaction results in a short amplification product and a long amplification product, wherein each of the plurality of primers comprises one or more tag sequences.
    Type: Application
    Filed: September 19, 2019
    Publication date: July 16, 2020
    Inventors: Kathryn M. Stephens, Cydne Holt, Carey Davis, Anne Jager, Paulina Walichiewicz, Yonmee Han, David Silva, Min-Jui Richard Shen, Sasan Amini, Frank J. Steemers
  • Publication number: 20200208144
    Abstract: Embodiments provided herein relate to methods and compositions for next generation sequencing. Some embodiments include the preparation of a template library from a target nucleic acid using one-sided transposition, sequencing the template library, and capturing the contiguity information.
    Type: Application
    Filed: January 7, 2020
    Publication date: July 2, 2020
    Inventors: Frank J. Steemers, Jeffrey S. Fisher, Kevin L. Gunderson, Sasan Amini, Christian Gloeckner
  • Patent number: 10679725
    Abstract: The present invention relates to a combination of experimental and computational workflows that allow characterization of specific molecular mechanisms by which the microbiome contribute to skin health and skin age.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: June 9, 2020
    Assignee: PRODERMIQ, INC.
    Inventors: Dana Hosseini, Sasan Amini, Eveie Schwartz
  • Patent number: 10676794
    Abstract: Provided herein are methods and apparatus for the identification of pathogenic and non-pathogenic microorganisms in food and environmental samples. The disclosure solves existing challenges encountered in identifying food borne pathogens, including pathogens of the Salmonella, Campylobacter, Listeria, and Escherichia genera in a timely and efficient manner. The disclosure also provides methods for differentiating a transient versus a resident pathogen, correlating presence of non-pathogenic with pathogenic microorganisms, distinguishing live versus dead microorganisms by sequencing.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: June 9, 2020
    Assignee: Clear Labs, Inc.
    Inventors: Sasan Amini, Ramin Khaksar, Michael Taylor, Hossein Namazi, David Tran, Christopher Haney, Pavan Vaidyanathan, Sima Mortazavi, Adam Allred
  • Publication number: 20200157530
    Abstract: Embodiments of the present invention relate to sequencing nucleic acids. In particular, embodiments of the methods and compositions provided herein relate to preparing nucleic acid templates and obtaining sequence data therefrom.
    Type: Application
    Filed: January 6, 2020
    Publication date: May 21, 2020
    Inventors: Frank J. Steemers, Sasan Amini, Kevin L. Gunderson, Natasha Pignatelli, Igor Goryshin
  • Publication number: 20200102600
    Abstract: Embodiments of the present invention relate to a combination of experimental and computational workflows that allow characterization of skin and subcutaneous tissue microbial flora and its associated metabolome, aiming to first evaluate an individual's skin and subcutaneous tissue to determine if any skin condition is as a result of an imbalance or absence of commensal or mutualistic microorganisms or their associated metabolites. In particular, embodiments of the methods and the associated computational platform provided herein relate to conducting a customized or personalized test and obtaining customized or personalized information regarding the skin and subcutaneous tissue flora and its associated metabolome there from. This may be accomplished by simultaneously identifying hundreds of microorganisms or metabolites on an individual's skin and subcutaneous tissue and comparing the resulting profile to a previously compiled healthy profile from our database of skin profiles.
    Type: Application
    Filed: March 9, 2018
    Publication date: April 2, 2020
    Inventors: Sasan AMINI, Dana HOSSEINI
  • Patent number: 10597714
    Abstract: Provided herein are methods and apparatus for the identification of pathogenic and non-pathogenic microorganisms in food and environmental samples. The disclosure solves existing challenges encountered in identifying food borne pathogens, including pathogens of the Salmonella, Campylobacter, Listeria, and Escherichia genera in a timely and efficient manner. The disclosure also provides methods for differentiating a transient versus a resident pathogen, correlating presence of non-pathogenic with pathogenic microorganisms, distinguishing live versus dead microorganisms by sequencing.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: March 24, 2020
    Assignee: Clear Labs, Inc.
    Inventors: Sasan Amini, Ramin Khaksar, Michael Taylor, Shadi Shokralla, Christopher Haney, Pavan Vaidyanathan, Adam Allred, David Tran, Hossein Namazi, Julius Barsi
  • Patent number: 10577603
    Abstract: Embodiments provided herein relate to methods and compositions for next generation sequencing. Some embodiments include the preparation of a template library from a target nucleic acid using one-sided transposition, and sequencing the template library.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: March 3, 2020
    Assignee: Illumina, Inc.
    Inventors: Frank J. Steemers, Jeffrey S. Fisher, Kevin L. Gunderson, Sasan Amini, Christian Gloeckner
  • Patent number: 10557133
    Abstract: Embodiments of the present invention relate to sequencing nucleic acids. In particular, embodiments of the methods and compositions provided herein relate to preparing nucleic acid templates and obtaining sequence data therefrom.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: February 11, 2020
    Assignee: ILLUMINA, INC.
    Inventors: Frank J. Steemers, Sasan Amini, Kevin L. Gunderson, Natasha Pignatelli, Igor Goryshin
  • Publication number: 20190309360
    Abstract: A method of sequencing a target nucleic acid polymer by (a) modifying a target nucleic acid polymer to produce a modified nucleic acid polymer; (b) producing fragments of the modified nucleic acid polymer, wherein the fragments are attached to locations on a solid support surface (c) determining nucleotide sequences from the fragments at the locations; and (d) producing a representation of the nucleotide sequence for the target nucleic acid polymer based on the nucleotide sequences from the fragments and the relative distances between the locations on the solid support surface.
    Type: Application
    Filed: March 18, 2019
    Publication date: October 10, 2019
    Inventors: Jeffrey S. Fisher, Frank J. Steemers, Sasan Amini, Kevin L. Gunderson
  • Publication number: 20190292577
    Abstract: Described herein are systems, methods, and compositions for treating a skin condition in an individual. A system or method is used to determine a skin flora of an individual and a sensitivity of the skin flora to a treatment modality. A composition is then customized based on the sensitivity of the skin flora to the treatment modality.
    Type: Application
    Filed: March 26, 2019
    Publication date: September 26, 2019
    Inventors: Sasan AMINI, Dana HOSSEINI
  • Patent number: 10422002
    Abstract: Embodiments disclosed herein provide methods for constructing a DNA profile comprising: providing a nucleic acid sample, amplifying the nucleic acid sample with a plurality of primers that specifically hybridize to at least one target sequence comprising a SNP and at least one target sequence comprising a tandem repeat, and determining the genotypes of the at least one SNP and at least one tandem repeat in the amplification products, thereby constructing the DNA profile of the nucleic acid sample. Embodiments disclosed herein further provide a plurality of primers that specifically hybridize to at least one short target sequence and at least one long target sequence in a nucleic acid sample, wherein amplifying the nucleic acid sample using the plurality of primers in a single reaction results in a short amplification product and a long amplification product, wherein each of the plurality of primers comprises one or more tag sequences.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: September 24, 2019
    Assignee: ILLUMINA, INC.
    Inventors: Kathryn M. Stephens, Cydne Holt, Carey Davis, Anne Jager, Paulina Walichiewicz, Yonmee Han, David Silva, Min-Jui Richard Shen, Sasan Amini, Frank J. Steemers
  • Publication number: 20190203287
    Abstract: Provided herein are methods and apparatus for the identification of pathogenic and non-pathogenic microorganisms in food and environmental samples. The disclosure solves existing challenges encountered in identifying food borne pathogens, including pathogens of the Salmonella, Campylobacter, Listeria, and Escherichia genera in a timely and efficient manner. The disclosure also provides methods for differentiating a transient versus a resident pathogen, correlating presence of non-pathogenic with pathogenic microorganisms, distinguishing live versus dead microorganisms by sequencing.
    Type: Application
    Filed: January 30, 2019
    Publication date: July 4, 2019
    Inventors: Sasan AMINI, Ramin KHAKSAR, Michael TAYLOR, Shadi SHOKRALLA, Christopher HANEY, Pavan VAIDYANATHAN, Stephanie POLLARD, Adam ALLRED, Sima MORTAZAVI, David TRAN, Hossein NAMAZI, Julius BARSI
  • Publication number: 20190203267
    Abstract: Provided herein are methods and apparatus for the identification of pathogenic and non-pathogenic microorganisms in food and environmental samples. The disclosure solves existing challenges encountered in identifying food borne pathogens, including pathogens of the Salmonella, Campylobacter, Listeria, and Escherichia genera in a timely and efficient manner. The disclosure also provides methods for differentiating a transient versus a resident pathogen, correlating presence of non-pathogenic with pathogenic microorganisms, distinguishing live versus dead microorganisms by sequencing.
    Type: Application
    Filed: March 21, 2018
    Publication date: July 4, 2019
    Inventors: Sasan AMINI, Ramin KHAKSAR, Michael TAYLOR, Hossein NAMAZI, Stephanie POLLARD, Shadi SHOKRALLA
  • Publication number: 20190204317
    Abstract: Provided herein are methods and apparatus for the identification of pathogenic and non-pathogenic microorganisms in food and environmental samples. The disclosure solves existing challenges encountered in identifying food borne pathogens, including pathogens of the Salmonella, Campylobacter, Listeria, and Escherichia genera in a timely and efficient manner. The disclosure also provides methods for differentiating a transient versus a resident pathogen, correlating presence of non-pathogenic with pathogenic microorganisms, distinguishing live versus dead microorganisms by sequencing.
    Type: Application
    Filed: August 3, 2018
    Publication date: July 4, 2019
    Inventors: Sasan AMINI, Ramin KHAKSAR, Michael TAYLOR, Hossein NAMAZI, David TRAN, Christopher HANEY, Pavan VAIDYANATHAN, Sima MORTAZAVI, Adam ALLRED
  • Patent number: 10246704
    Abstract: Provided herein are methods and apparatus for the identification of pathogenic and non-pathogenic microorganisms in food and environmental samples. The disclosure solves existing challenges encountered in identifying food borne pathogens, including pathogens of the Salmonella, Campylobacter, Listeria, and Escherichia genera in a timely and efficient manner. The disclosure also provides methods for differentiating a transient versus a resident pathogen, correlating presence of non-pathogenic with pathogenic microorganisms, distinguishing live versus dead microorganisms by sequencing.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: April 2, 2019
    Assignee: Clear Labs, Inc.
    Inventors: Sasan Amini, Ramin Khaksar, Michael Taylor, Shadi Shokralla, Hossein Namazi, David Tran