Patents by Inventor Sascha KNAUER

Sascha KNAUER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing peptides
    Patent number: 11976094
    Abstract: A method for preparing peptides is disclosed, the method comprising a step of forming a peptide bond wherein the carboxyl group of a first amino acid or first peptide is activated and an amino group of the first activated amino acid or first peptide is protected by a protecting group having a water-solubility enhancing group and the activated carboxyl group of the first amino acid or first peptide is reacted with an amino group of a second amino acid or second peptide wherein said carboxyl group of the first amino acid or first peptide is activated in the absence of the second amino acid or second peptide. Peptides comprising a protecting group having a water-solubility enhancing group being bound to the amino group and an activated or free carboxyl group are also disclosed.
    Type: Grant
    Filed: March 28, 2022
    Date of Patent: May 7, 2024
    Assignee: Sulfotools GmbH
    Inventor: Sascha Knauer
  • Method for peptide synthesis and apparatus for carrying out a method for solid phase synthesis of peptides
    Patent number: 11466050
    Abstract: The invention relates to a method for peptide synthesis, wherein said method comprises the steps of reacting a first amino acid or a first peptide with an ?-amine protected second amino acid in a solvent selected from the group consisting of water, alcohol, and a mixture of water and alcohol, and removing the ?-amine protecting group with a deprotecting solution. The invention further relates to protective agents, their use and an apparatus for carrying out a method for solid phase synthesis of peptides.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: October 11, 2022
    Assignee: SULFOTOOLS GMBH
    Inventors: Sascha Knauer, Tobias Michael Louis Roese, Olga Avrutina, Harald Kolmar, Christina Uth
  • METHOD FOR PREPARING PEPTIDES
    Publication number: 20220220151
    Abstract: A method for preparing peptides is disclosed, the method comprising a step of forming a peptide bond wherein the carboxyl group of a first amino acid or first peptide is activated and an amino group of the first activated amino acid or first peptide is protected by a protecting group having a water-solubility enhancing group and the activated carboxyl group of the first amino acid or first peptide is reacted with an amino group of a second amino acid or second peptide wherein said carboxyl group of the first amino acid or first peptide is activated in the absence of the second amino acid or second peptide. Peptides comprising a protecting group having a water-solubility enhancing group being bound to the amino group and an activated or free carboxyl group are also disclosed.
    Type: Application
    Filed: March 28, 2022
    Publication date: July 14, 2022
    Inventor: Sascha Knauer
  • Method for preparing peptides
    Patent number: 11319340
    Abstract: The invention relates to a method for preparing peptides comprising the step of forming a peptide bond wherein the carboxyl group of a first amino acid or first peptide is activated and an amino group of the first activated amino acid or first peptide is protected by a protecting group having a water-solubility enhancing group and the activated carboxyl group of the first amino acid or first peptide is reacted with an amino group of a second amino acid or second peptide wherein said carboxyl group of the first amino acid or first peptide is activated in the absence of the second amino acid or second peptide. The invention further relates to peptides comprising a protecting group having a water-solubility enhancing group being bound to the amino group and an activated or free carboxyl group.
    Type: Grant
    Filed: November 23, 2018
    Date of Patent: May 3, 2022
    Assignee: Sulfotools GmbH
    Inventor: Sascha Knauer
  • Method for Preparing Peptides
    Publication number: 20200377548
    Abstract: The invention relates to a method for preparing peptides comprising the step of forming a peptide bond wherein the carboxyl group of a first amino acid or first peptide is activated and an amino group of the first activated amino acid or first peptide is protected by a protecting group having a water-solubility enhancing group and the activated carboxyl group of the first amino acid or first peptide is reacted with an amino group of a second amino acid or second peptide wherein said carboxyl group of the first amino acid or first peptide is activated in the absence of the second amino acid or second peptide. The invention further relates to peptides comprising a protecting group having a water-solubility enhancing group being bound to the amino group and an activated or free carboxyl group.
    Type: Application
    Filed: November 23, 2018
    Publication date: December 3, 2020
    Inventor: Sascha Knauer
  • METHOD FOR PEPTIDE SYNTHESIS AND APPARATUS FOR CARRYING OUT A METHOD FOR SOLID PHASE SYNTHESIS OF PEPTIDES
    Publication number: 20170218010
    Abstract: The invention relates to a method for peptide synthesis, wherein said method comprises the steps of reacting a first amino acid or a first peptide with an ?-amine protected second amino acid in a solvent selected from the group consisting of water, alcohol, and a mixture of water and alcohol, and removing the ?-amine protecting group with a deprotecting solution. The invention further relates to protective agents, their use and an apparatus for carrying out a method for solid phase synthesis of peptides.
    Type: Application
    Filed: September 29, 2015
    Publication date: August 3, 2017
    Inventors: Sascha KNAUER, Tobias Michael Louis ROESE, Olga AVRUTINA, Harald KOLMAR, Christina UTH