Patents by Inventor Sascha KUPKE

Sascha KUPKE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INFLUENZA VIRUS DEFECTIVE INTERFERING PARTICLES FOR USE IN THE PROPHYLACTIC OR THERAPEUTIC TREATMENT OF CORONAVIRIDAE INFECTION
    Publication number: 20240131094
    Abstract: In The present invention relates in a first aspect to the use of influenza virus defective interfering particles in the prophylactic or therapeutic treatment of coronaviridae infection. In particular, it has been recognized that defective interfering particles of influenza A have beneficial effects in the treatment of SARS coronavirus infection, in particular, SARS-CoV-2 infection. Further, the present invention relates to a pharmaceutical composition for use in treating coronaviridae infection, in particular SARS-CoV-2. In a further aspect, methods for the prophylactic or therapeutic treatments of coronaviridae based on the administration of DIFs are disclosed.
    Type: Application
    Filed: February 18, 2022
    Publication date: April 25, 2024
    Inventors: Sascha KUPKE, Udo REICHL, Marc Dominique HEIN, Dunja BRUDER, ulfert RAND
  • Protective interfering nucleic acid molecule and virus-like particle, viral vector, or virus particle containing the same as well as pharmaceutical composition containing the protective interfering nucleic acid and its use
    Patent number: 11274304
    Abstract: In a first aspect, the present invention relates to an isolated nucleic acid molecule, in particular, an RNA molecule containing particular substitutions. In a further aspect, the present invention relates to a composition comprising the same as well as virus-like particle, viral vector or virus particle containing the nucleic acid molecule according to the present invention. The virus-like particle, the viral vector or the virus particle is suitable for use as a medicament in particular for treating viral infection. Further, a pharmaceutical composition is provided in particular suitable for use as a pharmaceutical prophylactic vaccine containing the virus-like particle, viral vector or the virus particle or the nucleic acid molecule according to the present invention.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: March 15, 2022
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Sascha Kupke, Timo Frensing, Pawel Zmora, Udo Reichl
  • Protective Interfering Nucleic Acid Molecule and Virus-Like Particle, Viral Vector, or Virus Particle Containing the same as well as Pharmaceutical Composition Containing the Protective Interfering Nucleic Acid and its use
    Publication number: 20200392504
    Abstract: In a first aspect, the present invention relates to an isolated nucleic acid molecule, in particular, an RNA molecule containing particular substitutions. In a further aspect, the present invention relates to a composition comprising the same as well as virus-like particle, viral vector or virus particle containing the nucleic acid molecule according to the present invention. The virus-like particle, the viral vector or the virus particle is suitable for use as a medicament in particular for treating viral infection. Further, a pharmaceutical composition is provided in particular suitable for use as a pharmaceutical prophylactic vaccine containing the virus-like particle, viral vector or the virus particle or the nucleic acid molecule according to the present invention.
    Type: Application
    Filed: March 5, 2019
    Publication date: December 17, 2020
    Inventors: Sascha KUPKE, Timo FRENSING, Pawel ZMORA, Udo REICHL