Patents by Inventor Sascha Rutz

Sascha Rutz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Efficient TCR gene editing in T lymphocytes
    Patent number: 12239664
    Abstract: The present disclosure relates to engineered T cells and methods of making and using the same, as well as reagents for making the engineered T cells.
    Type: Grant
    Filed: March 24, 2022
    Date of Patent: March 4, 2025
    Assignee: GENENTECH, INC.
    Inventors: Sascha Rutz, Benjamin Joseph Haley, Shravan Madireddi, Soyoung Oh, David Shaw, Kate Halliwell Senger
  • Anti-C-C motif chemokine receptor 8 (CCR8) antibodies and methods of use
    Patent number: 12240910
    Abstract: The present disclosure provides anti-CCR8 antibodies, and compositions and methods of their preparation and use.
    Type: Grant
    Filed: July 13, 2022
    Date of Patent: March 4, 2025
    Assignee: Genentech, Inc.
    Inventors: Gautham Gampa, Iraj Hosseini, Mahrukh Huseni, James Thomas Koerber, Jian Mehr-Dean Payandeh, Sascha Rutz, Yonglian Sun, Cecilia P. C. Chiu, Teresita Arenzana Delfino
  • ANTI-C-C MOTIF CHEMOKINE RECEPTOR 8 (CCR8) ANTIBODIES AND METHODS OF USE
    Publication number: 20230049152
    Abstract: The present disclosure provides anti-CCR8 antibodies, and compositions and methods of their preparation and use.
    Type: Application
    Filed: July 13, 2022
    Publication date: February 16, 2023
    Applicant: GENENTECH, INC.
    Inventors: Gautham Gampa, Iraj Hosseini, Mahrukh Huseni, James T. Koerber, Jian Mehr-Dean Payandeh, Sascha Rutz, Yonglian Sun, Cecilia P. C. Chiu, Teresita A. Delfino
  • EFFICIENT TCR GENE EDITING IN T LYMPHOCYTES
    Publication number: 20230041268
    Abstract: The present disclosure relates to engineered T cells and methods of making and using the same, as well as reagents for making the engineered T cells.
    Type: Application
    Filed: March 24, 2022
    Publication date: February 9, 2023
    Inventors: Sascha Rutz, Benjamin Joseph Haley, Shravan Madireddi, Soyoung Oh, David Shaw, Kate Halliwell Senger
  • Methods of modulating interleukin-22 and immune response by notch regulators
    Patent number: 8709710
    Abstract: The invention relates to the use of notch regulators for modulating IL-22 production in T-cells, by influencing the activity or activation of the notch signal path. The invention further relates to the use of modulating the immune response, primarily in case of infection reactions. The invention in particular relates to the use for treating illnesses associated with infections. The invention further relates to the use for reducing IL-22 production in T-cells.
    Type: Grant
    Filed: February 16, 2010
    Date of Patent: April 29, 2014
    Assignee: Deutsches Rheuma-Forschungszentrum Berlin
    Inventors: Alexander Scheffold, Sascha Rutz, Frederick Heinrich
  • USE OF NOTCH REGULATORS FOR MODULATING THE IMMUNE RESPONSE BY INDUCTION/SUPPRESSION OF INTERLEUKIN-22
    Publication number: 20120045458
    Abstract: The invention relates to the use of notch regulators for modulating IL-22 production in T-cells, by influencing the activity or activation of the notch signal path. The invention further relates to the use of modulating the immune response, primarily in case of infection reactions. The invention in particular relates to the use for treating illnesses associated with infections. The invention further relates to the use for reducing IL-22 production in T-cells.
    Type: Application
    Filed: February 16, 2010
    Publication date: February 23, 2012
    Applicant: DEUTSCHES RHEUMA-FORSCHUNGSZENTRUM BERLIN
    Inventors: Alexander Scheffold, Sascha Rutz, Frederick Heinrich