Patents by Inventor Sascha Weggen
Sascha Weggen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20080021085Abstract: The invention provides a method of preventing, delaying, or reversing the progression of Alzheimer's disease by administering an A?42 lowering agent to a mammal under conditions in which levels of A?42 are selectively reduced, levels of A?38 are increased, and levels of A?40 are unchanged. The invention provides methods and materials for developing and identifying A?42 lowering agents. In addition, the invention provides methods for identifying agents that increase the risk of developing, or hasten progression of, Alzheimer's disease. The invention also provides compositions of A?42 lowering agents and antioxidants, A?42 lowering agents and non-selective secretase inhibitors, as well as A?42 lowering agents and acetylcholinesterase inhibitors.Type: ApplicationFiled: June 21, 2007Publication date: January 24, 2008Applicants: Mayo Foundation for Medical Education and Research, The Regents of The University of CaliforniaInventors: Edward Koo, Todd Golde, Douglas Galasko, Sascha Weggen
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Publication number: 20070253905Abstract: The invention provides a method of preventing, delaying, or reversing the progression of Alzheimer's disease by administering an A?42 lowering agent to a mammal under conditions in which levels of A?42 are selectively reduced, levels of A?38 are increased, and levels of A?40 are unchanged. The invention provides methods and materials for developing and identifying A?42 lowering agents. In addition, the invention provides methods for identifying agents that increase the risk of developing, or hasten progression of, Alzheimer's disease. The invention also provides compositions of A?42 lowering agents and antioxidants, A?42 lowering agents and non-selective secretase inhibitors, as well as A?42 lowering agents and acetylcholinesterase inhibitors.Type: ApplicationFiled: April 26, 2007Publication date: November 1, 2007Applicants: Mayo Foundation for Medical Education, The Regents of the University of CaliforniaInventors: Edward Koo, Todd Golde, Sascha Weggen
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Publication number: 20070253906Abstract: The invention provides a method of preventing, delaying, or reversing the progression of Alzheimer's disease by administering an A?42 lowering agent to a mammal under conditions in which levels of A?42 are selectively reduced, levels of A?38 are increased, and levels of A?40 are unchanged. The invention provides methods and materials for developing and identifying A?42 lowering agents. In addition, the invention provides methods for identifying agents that increase the risk of developing, or hasten progression of, Alzheimer's disease. The invention also provides compositions of A?42 lowering agents and antioxidants, A?42 lowering agents and non-selective secretase inhibitors, as well as A?42 lowering agents and acetylcholinesterase inhibitors.Type: ApplicationFiled: April 26, 2007Publication date: November 1, 2007Applicants: Mayo Foundation for Medical Education and Research, The Regents of the University of CaliforniaInventors: Edward Koo, Todd Golde, Sascha Weggen
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Patent number: 7097998Abstract: The invention provides a method of preventing, delaying, or reversing the progression of Alzheimer's disease by administering an A?42 lowering agent to a mammal under conditions in which levels of A?42 are selectively reduced, levels of A?38 are increased, and levels of A?40 are unchanged. The invention provides methods and materials for developing and identifying A?42 lowering agents. In addition, the invention provides methods for identifying agents that increase the risk of developing, or hasten progression of, Alzheimer's disease. The invention also provides compositions of A?42 lowering agents and antioxidants, A?42 lowering agents and non-selective secretase inhibitors, as well as A?42 lowering agents and acetylcholinesterase inhibitors.Type: GrantFiled: August 27, 2004Date of Patent: August 29, 2006Assignees: The Regents of the University of California, Mayo Foundation for Medical Education and ResearchInventors: Edward Hao Mang Koo, Todd E. Golde, Sascha Weggen
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Publication number: 20060004086Abstract: The invention provides a method of preventing, delaying, or reversing the progression of Alzheimer's disease by administering an A?42 lowering agent to a mammal under conditions in which levels of A?42 are selectively reduced, levels of A?38 are increased, and levels of A?40 are unchanged. The invention provides methods and materials for developing and identifying A?42 lowering agents. In addition, the invention provides methods for identifying agents that increase the risk of developing, or hasten progression of, Alzheimer's disease. The invention also provides compositions of A?42 lowering agents and antioxidants, A?42 lowering agents and non-selective secretase inhibitors, as well as A?42 lowering agents and acetylcholinesterase inhibitors.Type: ApplicationFiled: June 28, 2005Publication date: January 5, 2006Applicants: Mayo Foundation for Medical Education and Research, The Regents of The University of CaliforniaInventors: Edward Mang Koo, Todd Golde, Douglas Galasko, Sascha Weggen
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Patent number: 6911466Abstract: The invention provides a method of preventing, delaying, or reversing the progression of Alzheimer's disease by administering an A?42 lowering agent to a mammal under conditions in which levels of A?42 are selectively reduced, levels of A?38 are increased, and levels of A?40 are unchanged. The invention provides methods and materials for developing and identifying A?42 lowering agents. In addition, the invention provides methods for identifying agents that increase the risk of developing, or hasten progression of, Alzheimer's disease. The invention also provides compositions of A?42 lowering agents and antioxidants, A?42 lowering agents and non-selective secretase inhibitors, as well as A?42 lowering agents and acetylcholinesterase inhibitors.Type: GrantFiled: December 7, 2001Date of Patent: June 28, 2005Assignees: Mayo Foundation for Medical Education and Research, The Regents of the University of CaliforniaInventors: Edward Hao Mang Koo, Todd Eliot Golde, Douglas Roger Galasko, Sascha Weggen