Patents by Inventor Sasha Mayer

Sasha Mayer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060040882
    Abstract: Polynucleotide delivery-enhancing polypeptides are admixed or complexed with, or conjugated to, nucleic acids for enhancing delivery the nucleic acids into cells. The transported nucleic acids are active in target cells as small inhibitory nucleic acids (siNAs) that modulate expression of target genes, mediated at least in part by RNA interference (RNAi). The siNA/polypeptide compositions and methods of the invention provide effective tools to modulate gene expression and alter phenotype in mammalian cells, including by altering phenotype in a manner that eliminates disease symptoms or alters disease potential in targeted cells or subject individuals to which the siNA/polypeptide compositions are administered.
    Type: Application
    Filed: May 4, 2005
    Publication date: February 23, 2006
    Inventors: Lishan Chen, Kunyuan Cui, Yuching Chen, Sasha Mayer
  • Publication number: 20060035815
    Abstract: What is disclosed is a pharmaceutical composition for administration of a double stranded ribonucleic acid (dsRNA) molecule to an animal, comprising the dsRNA molecule and a peptide, wherein the dsRNA molecule comprises about 10 to about 40 base pairs, wherein the peptide comprises about 5 to about 40 amino acids and consists of all or part of the amino acid sequence KGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQ (SEQ ID NO: 59), and wherein the peptide binds to the dsRNA molecule.
    Type: Application
    Filed: September 8, 2005
    Publication date: February 16, 2006
    Inventors: Lishan Chen, Kunyuan Cui, Michael Houston, Sasha Mayer, Yuching Chen