Abstract: The present invention is directed to a new kind of medicinal value or health care function of Eurycoma longifolia extracts, particularly in the treatment or alleviation symptoms and/or conditions associated to hormonal imbalance in females, including menopause and its related symptoms. In one aspect, the present invention discloses the use of a composition comprising a therapeutically effective amount of Eurycoma longifolia extract in the manufacture of a medicament for the alleviation of symptoms and/or conditions associated to hormonal imbalance in females, including menopause and its related symptoms. The alleviation of the symptoms and/or conditions according to the present invention is characterised by inducing a change in the hormonal contents of estrogen, progesterone, follicle stimulating hormone (FSH) and luteinizing hormone (LH). Also disclosed is the use of a pharmaceutical composition comprising the therapeutically effective amount of Eurycoma longifolia extract.

Abstract: The present invention is directed to a new kind of medicinal value or health care function of Eurycoma longifolia extracts, particularly in the treatment or alleviation symptoms and/or conditions associated to hormonal imbalance in females, including menopause and its related symptoms. In one aspect, the present invention discloses the use of a composition comprising a therapeutically effective amount of Eurycoma longifolia extract in the manufacture of a medicament for the alleviation of symptoms and/or conditions associated to hormonal imbalance in females, including menopause and its related symptoms. The alleviation of the symptoms and/or conditions according to the present invention is characterised by inducing a change in the hormonal contents of estrogen, progesterone, follicle stimulating hormone (FSH) and luteinizing hormone (LH). Also disclosed is the use of a pharmaceutical composition comprising the therapeutically effective amount of Eurycoma longifolia extract.

Abstract: Method for producing an extract or extract formulation of the fruit of Canarium odontophyllum comprising or consisting of the following steps: (i) providing fruit material from Canarium odontophyllum, wherein said fruit material essentially consists of the endocarp of the seeds of Canarium odontophyllum, (i-a) optionally drying the fruit material provided in step (i), (ii) extracting the fruit material provided in step (i) or (i-a) with a mixture essentially consisting or consisting of water and an alcohol having 1 to 3 carbon atoms or consisting water and acetonitrile, (iii) optionally partially or fully removing the alcohol having 1 to 3 carbon atoms of step (ii), and optionally adding an organic solvent of medium polarity to said aqueous residue and extracting the aqueous residue with said organic solvent or a supercritical solvent, such as supercritical carbon dioxide thereby obtaining an enriched extract, (iv) optionally mixing the extract obtained in step (ii) or the enriched extract obtained in