Patents by Inventor Sasikanth Manne

Sasikanth Manne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IN VIVO CRISPR SCREENING SYSTEM FOR DISCOVERING THERAPEUTIC TARGETS IN CD8 T CELLS
    Publication number: 20250011764
    Abstract: The present disclosure provides modified immune cells or precursors thereof comprising disrupted Fli1. Compositions and methods of treatment are also provided. The disclosure also provides methods for screening T cells, including assessing T cell exhaustion.
    Type: Application
    Filed: February 23, 2022
    Publication date: January 9, 2025
    Inventors: E. John Wherry, Zeyu Chen, Junwei Shi, Omar Khan, Josephine R. Giles, Sasikanth Manne