Patents by Inventor Sasson Cohen

Sasson Cohen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiarrhythmic quinuclidine carboxylic acid xylidide and method of producing the same and similar compounds
    Patent number: 4146628
    Abstract: The invention relates to the compound 2-6-xylidide of quinuclidine-3-carboxylic acid and its pharmaceutically acceptable salts, such as the hydrochloride, which have been found to be effective antiarrhythmic agents. The invention further relates to the production of this antiarrhythmic compound which method is applicable also to the production of related compounds which, however, do not have antiarrhythmic action, e.g. the quinuclidine-2-carboxylic acid xylidides. The compounds are produced according to this method by reacting the quinuclidine carboxylic acid in anhydrous chloroform and oxalyl chloride with the dimethylaniline. The desired compound is produced in high yield with a high degree of purity.
    Type: Grant
    Filed: August 4, 1977
    Date of Patent: March 27, 1979
    Inventors: Edna Oppenheimer, Eliezer Kaplinsky, Sasson Cohen
  • Pharmaceutical composition for treating glaucoma and compound 1,3,2-dioxaphospheringnes
    Patent number: 4112082
    Abstract: Organo-phosphorus compounds of the general formula ##STR1## wherein Z is a member selected from ##STR2## wherein R and R' are each selected from hydrogen and lower alkyl, R" designates a member selected from methyl and ethyl, and X.sup.- is an anion may be used as active ingredient in pharmaceutical and pesticidal, especially acaricidal and fungicidal, compositions of matter of low mammalian toxicity.
    Type: Grant
    Filed: October 30, 1975
    Date of Patent: September 5, 1978
    Assignee: The State of Israel, Prime Minister's Office, The Israel Institute for Biological Research
    Inventors: Yacov Ashani, Gavriel Amitai, Yona Grunfeld, Asher Kalir, Sasson Cohen
  • Spiro (1,3-dioxolane-4,3') quinuclidine compounds
    Patent number: 4104397
    Abstract: Novel spiro (1,3-dioxolane-4,3') quinuclidine compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2, which may be identical or different, each designates a member of the group hydrogen, alkyl or aryl; a process for the production of these and pharmaceutical compositions of matter containing such compound as active ingredient.
    Type: Grant
    Filed: February 6, 1976
    Date of Patent: August 1, 1978
    Assignee: The Purdue Frederick Company
    Inventors: Sasson Cohen, Abraham Fisher
  • 6-Oxa-1-aza tricyclo dodecan-5-ones as psychomotor stimulators
    Patent number: 4083985
    Abstract: Compounds of the general formula ##STR1## wherein X is selected from the group consisting of oxygen CH.sub.2 and CH radicals, and when X designates oxygen, R designates alkyl, isoalkyl, aralkyl, and substituted aryl groups and when X designates ##STR2## then R designates alkyl, phenyl or substituted phenyl group, and A--B is a single bond and when X designates >CH, and A--B is a double bond, R designates alkyl, phenyl or substituted phenyl groups and physiologically acceptable salts of these, and pharmaceutical compositions containing same as active ingredient.
    Type: Grant
    Filed: February 6, 1976
    Date of Patent: April 11, 1978
    Assignee: The Purdue Frederick Company
    Inventors: Sasson Cohen, Abraham Fisher