Patents by Inventor Sateesh Krishnamurthy

Sateesh Krishnamurthy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of improving RNAi in well-differentiated airway epithelia
    Patent number: 9987299
    Abstract: The present invention relates to methods of reducing a level of a target mRNA in a well-differentiated airway epithelial cell by contacting the cell with a facilitating agent followed by contacting the cell with a therapeutic RNAi agent, wherein the facilitating agent comprises a Platelet-activating factor receptor (PAFR) ligand.
    Type: Grant
    Filed: May 4, 2015
    Date of Patent: June 5, 2018
    Assignee: University of Iowa Research Foundation
    Inventors: Paul B. McCray, Jr., Beverly L. Davidson, Michael A. Apicella, Sateesh Krishnamurthy
  • Methods to enhance RNAi oligonucleotide delivery to respiratory epithelial cells
    Patent number: 9272016
    Abstract: The present invention relates to methods of reducing a level of a target mRNA in a well-differentiated airway epithelial cell by contacting the cell with a sensitizing agent followed by contacting the cell with a therapeutic RNAi agent.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: March 1, 2016
    Assignee: University of Iowa Research Foundation
    Inventors: Paul B. McCray, Jr., Beverly L. Davidson, Sateesh Krishnamurthy
  • METHODS OF IMPROVING RNAI IN WELL-DIFFERENTIATED AIRWAY EPITHELIA
    Publication number: 20150313924
    Abstract: The present invention relates to methods of reducing a level of a target mRNA in a well-differentiated airway epithelial cell by contacting the cell with a facilitating agent followed by contacting the cell with a therapeutic RNAi agent, wherein the facilitating agent comprises a Platelet-activating factor receptor (PAFR) ligand.
    Type: Application
    Filed: May 4, 2015
    Publication date: November 5, 2015
    Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Paul B. McCray, JR., Beverly L. Davidson, Michael A. Apicella, Sateesh Krishnamurthy
  • METHODS TO ENHANCE RNAI OLIGONUCLEOTIDE DELIVERY TO RESPIRATORY EPITHELIAL CELLS
    Publication number: 20130281372
    Abstract: The present invention relates to methods of reducing a level of a target mRNA in a well-differentiated airway epithelial cell by contacting the cell with a sensitizing agent followed by contacting the cell with a therapeutic RNAi agent.
    Type: Application
    Filed: March 14, 2013
    Publication date: October 24, 2013
    Applicant: University of Iowa Research Foundation
    Inventors: Paul B. McCray, JR., Beverly L. Davidson, Sateesh Krishnamurthy