Abstract: To more fully utilize the available bandwidth of a network link, network nodes in accordance with the present invention allow TDM data to be combined with packet data. A Packet/TDM cross connect switch, having both a TDM switch and a packet switch, is used in these embodiments. Data packets are transformed into TDM packet columns. The TDM packet columns are combined with standard TDM data columns in the payload of a TDM data frame. Data packets may be sorted based on a priority scheme, in which high priority data packets are given precedence over lower priority data. However, both high priority and low priority may be combined in a TDM packet column.

Abstract: This disclosure provides immunoglobulin binding molecules that specifically bind to human macrophage stimulating receptor (MST1 R, also referred to herein as recepteur d'origine Nantaise or RON), including antibodies and monospecific and multispecific single chain binding proteins having one or more other domains, such as one or more antibody constant region domains. Also provided are therapeutic applications of such binding proteins, such as for the treatment of cancer and inflammatory disorders.

Abstract: A method and apparatus for detecting hazardous gases.

Abstract: An apparatus to obtain zoned real-time gas concentration and location information from a plurality of gas detectors and provide compliance information along with exposure trends and warning information. Acquired concentration and location information can be stored in a common memory unit for efficient trend analysis and generation of compliance information.

Abstract: The present application provides novel binding proteins, including human binding proteins that specifically bind to the human ErbB2.

Abstract: This disclosure provides a multi-specific fusion protein composed of a CD86 antagonist binding domain and another binding domain that is an IL-10 agonist, an HLA-G agonist, an HGF agonist, an IL-35 agonist, a PD-1 agonist, a BTLA agonist, a LIGHT antagonist, a GITRL antagonist or a CD40 antagonist. The multi-specific fusion protein may also include an intervening domain that separates the other domains. This disclosure also provides polynucleotides encoding the multi-specific fusion proteins, compositions of the fusion proteins, and methods of using the multi-specific fusion proteins and compositions.

Abstract: Single chain fusion proteins that specifically bind to a TCR complex or a component thereof, such as TCR?, TCR?, or CD3?, along with compositions and methods of use thereof are provided.

Abstract: A system and method of monitoring zones for alarm conditions and automatically alerting individuals in a plurality of zones about the safety of a particular zone is provided. The method includes providing a site map of a predefined area, configuring a plurality of zones in the predefined area, receiving ambient condition data and location data from a plurality of wireless devices located in the predefined area, computing an alarm level for each zone in the plurality of zones based on the received ambient condition data and location data, and transmitting alert notifications to the plurality of wireless devices. The alert notification sent to each wireless device is based on the computed alarm level of the zone in which that wireless device is located relative to the computed alarm level of the other zones in the plurality of zones.

Abstract: A present invention relates to the synergistic herbal ophthalmic composition, which delays the onset and progression of cataract. The product is suitable for prophylactic treatment of cataract of different degree. The herbs are cleaned coarsely ground, weighed as per formula and extracted using different solvents preferably water, filtered or centrifuged to collect the clear filtrate and formulated in the form of sterile ophthalmic drops, gel, ointment, cream etc for said therapeutic purpose.

Abstract: The present invention relates to a synergistic herbal composition for lowering the intra ocular pressure in different types of glaucoma and process for the preparation of the same in pharmaceutically acceptable dosage forms.

Abstract: The present application provides novel binding proteins, including human binding proteins that specifically bind to the human ErbB2.

Abstract: To more fully utilize the available bandwidth of a network link, network nodes in accordance with the present invention allow TDM data to be combined with packet data. A Packet/TDM cross connect switch, having both a TDM switch and a packet switch, is used in these embodiments. Data packets are transformed into TDM packet columns. The TDM packet columns are combined with standard TDM data columns in the payload of a TDM data frame. Data packets may be sorted based on a priority scheme, in which high priority data packets are given precedence over lower priority data.

Abstract: To more fully utilize the available bandwidth of a network link, network nodes in accordance with the present invention allow TDM data to be combined with packet data. A Packet/TDM cross connect switch, having both a TDM switch and a packet switch, is used in these embodiments. Data packets are transformed into TDM packet columns. The TDM packet columns are combined with standard TDM data columns in the payload of a TDM data frame. Data packets may be sorted based on a priority scheme, in which high priority data packets are given precedence over lower priority data. However, both high priority and low priority may be combined in a TDM packet column.

Abstract: To better utilize the variable bandwidth of wireless links, a network node in accordance with the present invention escapes rigid bandwidth hierarchy of conventional TDM protocols, which is not suited for fully using the available bandwidth of a wireless link. Specifically, many embodiments of the present invention use TDM frames that have payloads, which do not strictly conform to the bandwidth hierarchy of conventional TDM protocols. For example, many embodiments of the present invention form TDM frames having a payload that is a non-integer multiple of a base bandwidth, such as OC-1/STS-1.

Abstract: The versatility provided by network nodes in accordance with the present invention allows the formation of networks using different types of links, links with differing bandwidth, data rates, and bit error rates, as well as both asymmetric and symmetric links. For example, a network can include a first network node coupled to a second network node with a wireless link. The network can include a third network node coupled to the second network node an optical link and coupled to the first network node by a wireless link. A fourth network node can be easily inserted between the third network node and the third network node using wireless links. The optical link between the second and third network nodes can operate at one bandwidth and the various wireless links would operate at other bandwidths depending on the environmental conditions between each pair of nodes.

Abstract: To provide the quality and reliability of a fiber optic link over a wireless link, network nodes in accordance with the present invention include a link quality management unit, which controls multiple transmission parameters of a wireless interface in response variable link conditions. For example, the link quality management unit of one embodiment of the present invention controls transmission power, modulation, and error correction. In general, a receiving network node provides feedback to a transmitting network node. Thus, in many embodiments of the present invention, the link quality management unit includes a signal quality detector, which measures a signal quality value, such as bit error rate, signal to noise ratio, or error vector magnitude. The measured signal quality is transmitted back to the transmitting node so that appropriate changes can be made to the transmission parameters.

Abstract: To more fully utilize the available bandwidth of a network link, network nodes in accordance with the present invention allow TDM data to be combined with packet data. A Packet/TDM cross connect switch, having both a TDM switch and a packet switch, is used in these embodiments. Data packets are transformed into TDM packet columns. The TDM packet columns are combined with standard TDM data columns in the payload of a TDM data frame. Data packets may be sorted based on a priority scheme, in which high priority data packets are given precedence over lower priority data.

Abstract: To provide the quality and reliability of a fiber optic link over a wireless link, network nodes in accordance with the present invention include a link quality management unit, which controls multiple transmission parameters of a wireless interface in response variable link conditions. For example, the link quality management unit of one embodiment of the present invention controls transmission power, modulation, and error correction. In general, a receiving network node provides feedback to a transmitting network node. Thus, in many embodiments of the present invention, the link quality management unit includes a signal quality detector, which measures a signal quality value, such as bit error rate, signal to noise ratio, or error vector magnitude. The measured signal quality is transmitted back to the transmitting node so that appropriate changes can be made to the transmission parameters.

Abstract: The versatility provided by network nodes in accordance with the present invention allows the formation of networks using different types of links, links with differing bandwidth, data rates, and bit error rates, as well as both asymmetric and symmetric links. For example, a network can include a first network node coupled to a second network node with a wireless link. The network can include a third network node coupled to the second network node an optical link and coupled to the first network node by a wireless link. A fourth network node can be easily inserted between the third network node and the third network node using wireless links. The optical link between the second and third network nodes can operate at one bandwidth and the various wireless links would operate at other bandwidths depending on the environmental conditions between each pair of nodes.

Abstract: To better utilize the variable bandwidth of wireless links, a network node in accordance with the present invention escapes rigid bandwidth hierarchy of conventional TDM protocols, which is not suited for fully using the available bandwidth of a wireless link. Specifically, many embodiments of the present invention use TDM frames that have payloads, which do not strictly conform to the bandwidth hierarchy of conventional TDM protocols. For example, many embodiments of the present invention form TDM frames having a payload that is a non-integer multiple of a base bandwidth, such as OC-1/STS-1.