Patents by Inventor Satheesh ELLIPILLI

Satheesh ELLIPILLI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNA nanoparticle for liver cancer treatment
    Patent number: 12662674
    Abstract: Disclosed herein are compositions and methods for targeted treatment of liver cancers with Paclitaxel and miR-122. The disclosed composition comprises RNA nanostructure conjugated to a hepatocyte targeting ligand, paclitaxel, and miR-122 for use in intracellular drug delivery to liver cancer cells. The RNA nanoparticle can involve three or more self-assembled synthetic RNA oligonucleotides that form a central core domain and at least three double-stranded arms arranged around the core domain and extending away from the central core domain.
    Type: Grant
    Filed: December 17, 2020
    Date of Patent: June 23, 2026
    Assignee: OHIO STATE INNOVATION FOUNDATION
    Inventors: Peixuan Guo, Satheesh Ellipilli, Hongzhi Wang, Congcong Xu, Xin Li
  • RNA NANOPARTICLE FOR LIVER CANCER TREATMENT
    Publication number: 20220372493
    Abstract: Disclosed herein are compositions and methods for targeted treatment of liver cancers with Paclitaxel and miR-122. The disclosed composition comprises RNA nanostructure conjugated to a hepatocyte targeting ligand, paclitaxel, and miR-122 for use in intracellular drug delivery to liver cancer cells. The RNA nanoparticle can involve three or more self-assembled synthetic RNA oligonucleotides that form a central core domain and at least three double-stranded arms arranged around the core domain and extending away from the central core domain.
    Type: Application
    Filed: December 17, 2020
    Publication date: November 24, 2022
    Inventors: Peixuan GUO, Satheesh ELLIPILLI, Hongzhi WANG, Congcong XU, Xin LI