Patents by Inventor Satheesh Nair

Satheesh Nair has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Imidazole prodrug LXR modulators
    Patent number: 8901106
    Abstract: Imidazole prodrugs, pharmaceutically acceptable salts, or isomers thereof, of the invention are disclosed, which are useful as modulators of the activity of liver X receptors (LXR). Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed.
    Type: Grant
    Filed: March 26, 2012
    Date of Patent: December 2, 2014
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ellen K. Kick, Michael J. Hageman, Victor R. Guarino, Ching-Chiang Su, Chenkou Wei, Jayakumar S. Warrier, Satheesh Nair
  • IMIDAZOLE PRODRUG LXR MODULATORS
    Publication number: 20140018321
    Abstract: Imidazole prodrugs, pharmaceutically acceptable salts, or isomers thereof, of the invention are disclosed, which are useful as modulators of the activity of liver X receptors (LXR). Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed.
    Type: Application
    Filed: March 26, 2012
    Publication date: January 16, 2014
    Inventors: Ellen K. Kick, Michael J. Hageman, Victor R. Guarino, Ching-Chiang Su, Chenkou Wei, Jayakumar S. Warrier, Satheesh Nair
  • Prodrugs of a piperidinyl derivative as modulators of chemokine receptor activity
    Patent number: 8410139
    Abstract: The present application describes prodrugs of the compound of formula (I): or stereoisomers or pharmaceutically acceptable salts thereof. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis using the prodrug compounds of the invention are disclosed.
    Type: Grant
    Filed: October 4, 2010
    Date of Patent: April 2, 2013
    Assignee: Bristol-Myers Squibb Company
    Inventors: John Hynes, Percy H. Carter, Lyndon A. M. Cornelius, T.G. Murali Dhar, John V. Duncia, Satheesh Nair, Joseph B. Santella, Jayakumar S. Warrier, Hong Wu
  • PRODRUGS OF A PIPERIDINYL DERIVATIVE AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
    Publication number: 20110082113
    Abstract: The present application describes prodrugs of the compound of formula (I): or stereoisomers or pharmaceutically acceptable salts thereof. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis using the prodrug compounds of the invention are disclosed.
    Type: Application
    Filed: October 4, 2010
    Publication date: April 7, 2011
    Inventors: John Hynes, Percy H. Carter, Lyndon A.M. Cornelius, T.G. Murali Dhar, John V. Duncia, Joseph B. Santella, Hong Wu, Satheesh Nair, Jayakumar S. Warrier
  • Method and system for research using computer based simultaneous comparison and contrasting of a multiplicity of subjects having specific attributes within specific contexts
    Patent number: 7908288
    Abstract: A method and system for an internet-based online research solution through the comparison and contrasting of a potentially infinite number of subjects having defined attributes within predefined as well as dynamic subject contexts; a method and system for searching a potentially infinite number of subjects against a customized set of attribute-value configurations to arrive at an appropriate set of subjects for further research; a method and system for an online research solution by which the user efficiently researches online using a highly customized search, collation, and compilation of comparison-contrast information; a Universal Research Framework that may be embedded within any externally managed information system and which enables the above three methods to be performed within the specific system for research.
    Type: Grant
    Filed: April 12, 2007
    Date of Patent: March 15, 2011
    Inventor: Satheesh Nair
  • Piperazine and Piperidine MGLUR5 Potentiators
    Publication number: 20100144710
    Abstract: Compounds of Formula I or pharmaceutically acceptable salts or solvates thereof, wherein A, B, D, Ar1, Ar2, R2, R3, R4, a, m and n are defined in the specification, methods for the use thereof, processes for making and pharmaceutical compositions containing the same.
    Type: Application
    Filed: February 28, 2008
    Publication date: June 10, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Jalaj Arora, Methvin Isaac, Abdelmalik Slassi, Louise Edwards, Satheesh Nair, Fupeng Ma
  • Method And System For Research Using Computer Based Simultaneous Comparison And Contrasting Of A Multiplicity Of Subjects Having Specific Attributes Within Specific Contexts
    Publication number: 20080256023
    Abstract: A method and system for an internet-based online research solution through the comparison and contrasting of a potentially infinite number of subjects having defined attributes within predefined as well as dynamic subject contexts; a method and system for searching a potentially infinite number of subjects against a customized set of attribute-value configurations to arrive at an appropriate set of subjects for further research; a method and system for an online research solution by which the user efficiently researches online using a highly customized search, collation, and compilation of comparison-contrast information; a Universal Research Framework that may be embedded within any externally managed information system and which enables the above three methods to be performed within the specific system for research.
    Type: Application
    Filed: April 12, 2007
    Publication date: October 16, 2008
    Inventor: Satheesh Nair
  • Methods for preparing 2,3,5,6-substituted 3h-pyrimidin-4-ones
    Publication number: 20070161792
    Abstract: Pyrimidinone compounds are disclosed. Methods of preparing the pyrimidinone compounds are also disclosed.
    Type: Application
    Filed: April 7, 2004
    Publication date: July 12, 2007
    Applicant: NPS PHARMACUETICALS, INC
    Inventors: Irina Shcherbakova, Manuel Balandria, Guangfei Huang, Otto Geoffroy, John Fox, Satheesh Nair