Patents by Inventor Sathesh Pangala Bhat

Sathesh Pangala Bhat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF BETA SECRETASE
    Publication number: 20210284659
    Abstract: The present invention relates to tricyclic inhibitors of beta-secretase having the structure shown in Formula (I) and (II) and the tautomers and the stereoisomeric forms thereof, wherein the radicals are as defined in the specification. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which beta-secretase is involved, such as Alzheimer's disease (AD), mild cognitive impairment, senility, dementia, dementia with Lewy bodies, Down's syndrome, dementia associated with stroke, dementia associated with Parkinson's disease, dementia associated with beta-amyloid, age-related macular degeneration, type 2 diabetes and other metabolic disorders.
    Type: Application
    Filed: March 6, 2018
    Publication date: September 16, 2021
    Inventors: Ann Marleen Vos, Daniel Oehlrich, Henricus Jacobus Maria Gijsen, Karl Shawn Watts, Sathesh Pangala Bhat, Peter Jacobus Johannes Antonius Buijnsters, Sven Franciscus Anna Van Brandt, Jesús Manuel Alcázar-Vaca
  • INHIBITORS OF BETA SECRETASE
    Publication number: 20200010482
    Abstract: The present invention relates to tricyclic inhibitors of beta-secretase having the structure shown in Formula (I) and (II) and the tautomers and the stereoisomeric forms thereof, wherein the radicals are as defined in the specification. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which beta-secretase is involved, such as Alzheimer's disease (AD), mild cognitive impairment, senility, dementia, dementia with Lewy bodies, Down's syndrome, dementia associated with stroke, dementia associated with Parkinson's disease, dementia associated with beta-amyloid, age-related macular degeneration, type 2 diabetes and other metabolic disorders.
    Type: Application
    Filed: March 6, 2018
    Publication date: January 9, 2020
    Inventors: Ann Marleen Vos, Daniel Oehlrich, Henricus Jacobus Maria Gijsen, Karl Shawn Watts, Sathesh Pangala Bhat, Frans Maria Alfons Van den Keybus