Patents by Inventor Sathyamoorthy BHASKAR

Sathyamoorthy BHASKAR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TARGETING OF MELANOCYTES FOR DELIVERING THERAPEUTIC OR DIAGNOSTIC AGENTS USING PROTEIN NANOCAGES
    Publication number: 20220062387
    Abstract: The present invention relates to protein nanocages comprising a melanocyte-targeting moiety and pharmaceutical compositions comprising the protein cages as well as methods for treating or diagnosing hyperpigmentation disorders or other melanocyte-related disorders using the protein nanocages or pharmaceutical compositions.
    Type: Application
    Filed: November 12, 2021
    Publication date: March 3, 2022
    Inventors: Sierin LIM, Sathyamoorthy BHASKAR, Steven THNG, Ambili KUNIYIL, Sarker MRIDUL
  • Targeting of melanocytes for delivering therapeutic or diagnostic agents using protein nanocages
    Patent number: 11202820
    Abstract: The present invention relates to protein nanocages comprising a melanocyte-targeting moiety and pharmaceutical compositions comprising the protein cages as well as methods for treating or diagnosing hyperpigmentation disorders or other melanocyte-related disorders using the protein nanocages or pharmaceutical compositions. In the preferred embodiment, the protein nanocage is composed of Bacillus stearothermophilus E2 protein of pyruvate dehydrogenase multi-enzyme complex (E2), with a skin penetrating and cell permeating SPACE moiety, and a melanocyte-targeting moiety of alpha melanocyte stimulating hormone.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: December 21, 2021
    Assignees: NANYANG TECHNOLOGICAL UNIVERSITY, NATIONAL SKIN CENTER (S) PTE LTD
    Inventors: Sierin Lim, Sathyamoorthy Bhaskar, Steven Thng, Ambili Kuniyil, Sarker Mridul
  • TARGETING OF MELANOCYTES FOR DELIVERING THERAPEUTIC OR DIAGNOSTIC AGENTS USING PROTEIN NANOCAGES
    Publication number: 20190030134
    Abstract: The present invention relates to protein nanocages comprising a melanocyte-targeting moiety and pharmaceutical compositions comprising the protein cages as well as methods for treating or diagnosing hyperpigmentation disorders or other melanocyte-related disorders using the protein nanocages or pharmaceutical compositions. In the preferred embodiment, the protein nanocage is composed of Bacillus stearothermophilus E2 protein of pyruvate dehydrogenase multi-enzyme complex (E2), with a skin penetrating and cell permeating SPACE moiety, and a melanocyte-targeting moiety of alpha melanocyte stimulating hormone.
    Type: Application
    Filed: September 25, 2015
    Publication date: January 31, 2019
    Inventors: Sierin LIM, Sathyamoorthy BHASKAR, Steven THNG, Ambili KUNIYIL, Sarker MRIDUL