Patents by Inventor Satish P. RamachandraRao

Satish P. RamachandraRao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and device for diagnosing organ injury
    Patent number: 10370719
    Abstract: The present disclosure relates to methods of collecting exosomes and microvesicles (EMV) from urine and isolating corresponding mRNA in order to diagnose and treat acute kidney injury (AKI). In particular, certain embodiments relate to the method of capturing EMV from urine applied to a filter device that is capable of capturing EMV. Nucleic acids such as mRNA can be isolated from the EMV using an oligo(dT)-coated plate designed to accommodate the filter device and then used for further molecular analysis. Quantification of the collected nucleic acids may then be used in the diagnosis and/or treatment of IBD.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: August 6, 2019
    Assignees: Hitachi Chemical Co., Ltd., Hitachi Chemical Co. America, Ltd., The Regents of the University of California
    Inventors: Satish P. RamachandraRao, Ravindra Lall Mehta, Masato Mitsuhashi, Taku Murakami
  • METHOD AND DEVICE FOR DIAGNOSING ORGAN INJURY
    Publication number: 20170335397
    Abstract: The present disclosure relates to methods of collecting exosomes and microvesicles (EMV) from urine and isolating corresponding mRNA in order to diagnose and treat acute kidney injury (AKI). In particular, certain embodiments relate to the method of capturing EMV from urine applied to a filter device that is capable of capturing EMV. Nucleic acids such as mRNA can be isolated from the EMV using an oligo(dT)-coated plate designed to accommodate the filter device and then used for further molecular analysis. Quantification of the collected nucleic acids may then be used in the diagnosis and/or treatment of IBD.
    Type: Application
    Filed: November 12, 2015
    Publication date: November 23, 2017
    Inventors: Satish P. RamachandraRao, Ravindra Lall Mehta, Masato Mitsuhashi, Taku Murakami