Abstract: The present disclosure relates to the field of synthesizing substantially pure varenicline and its intermediates. It also relates to the pharmaceutical compositions comprising varenicline and the method of use of these pharmaceutical compositions for smoking cessation.

Abstract: A distributed computing system is provided, including a source computing device implementing a source hypervisor executing a virtual machine, a source-side router coupled to the source hypervisor, a destination computing device implementing a destination hypervisor, and a destination-side router coupled to the destination hypervisor. The source hypervisor is connected to the destination hypervisor through a network. During a migration of the virtual machine from the source hypervisor to the destination hypervisor, the source-side router duplicates packets ingressing into the source-side router. The duplicated packets include a first set of packets and a second set of packets, where the first set of packets is routed to the virtual machine through the source hypervisor on the network, and the second set of packets is routed to the virtual machine through the destination hypervisor on the network.

Abstract: The present disclosure relates to the field of synthesizing substantially pure varenicline and its intermediates. It also relates to the pharmaceutical compositions comprising varenicline and the method of use of these pharmaceutical compositions for smoking cessation.

Abstract: The present disclosure relates to the field of synthesizing substantially pure varenicline and its intermediates. It also relates to the pharmaceutical compositions comprising varenicline and the method of use of these pharmaceutical compositions for smoking cessation.

Abstract: The present disclosure relates to the field of synthesizing substantially pure varenicline and its intermediates. It also relates to the pharmaceutical compositions comprising varenicline and the method of use of these pharmaceutical compositions for smoking cessation.

Abstract: The present disclosure relates to the field of synthesizing substantially pure varenicline and its intermediates. It also relates to the pharmaceutical compositions comprising varenicline and the method of use of these pharmaceutical compositions for smoking cessation.

Abstract: The present disclosure relates to the field of synthesizing substantially pure varenicline and its intermediates. It also relates to the pharmaceutical compositions comprising varenicline and the method of use of these pharmaceutical compositions for smoking cessation.

Abstract: The present disclosure relates to the field of synthesizing substantially pure varenicline and its intermediates. It also relates to the pharmaceutical compositions comprising varenicline and the method of use of these pharmaceutical compositions for smoking cessation.

Abstract: The present disclosure relates to the field of synthesizing substantially pure varenicline and its intermediates. It also relates to the pharmaceutical compositions comprising varenicline and the method of use of these pharmaceutical compositions for smoking cessation.

Abstract: The foregoing are among the objects attained by the invention which provides cloud native distributed, hierarchical methods and apparatus for the ingestion of data generated by a fully-instrumented manufacturing or industrial plants. The systems and methods employ an architecture that is capable of collecting and preliminarily processing data at the plant-level for self-learning detection of error (and other) conditions, and forwarding that data for more in depth processing in the cloud. The architecture takes into account the varied data throughput, storage and processing needs at each level of the hierarchy. The distributed and hierarchical system allows for the creation of a dynamic, real-time assessment of the behavior and health of assets and enables visibility and integrity into the design, manufacturing, operations and service of any asset. The use of that capability (referred to herein as PARCS™) allows for Systemic Asset Intelligence within an asset, plant, system and/or an ecosystem.

Abstract: The present disclosure relates to substituted amide compounds that are inhibitors of Fatty Acid Amide Hydrolase (FAAH), their stereoisomers, tautomers, prodrugs, polymorphs, solvates, pharmaceutically acceptable salts, and pharmaceutical compositions containing them.

Abstract: The present disclosure relates to substituted amide compounds that are inhibitors of Fatty Acid Amide Hydrolase (FAAH), their stereoisomers, tautomers, prodrugs, polymorphs, solvates, pharmaceutically acceptable salts, and pharmaceutical compositions containing them.

Abstract: A computer system and a method for analysis and visualization of signalling and metabolic pathways, comprising inter-related databases including external database, a pathway database for storing curated signalling interaction between the biological entities and biological entity data, said databases including a pathart database, a curator member to generate curated signalling interaction between the biological entities obtained from external sources, said pathway database comprising a hierarchical arrangement of signalling interactions among the biological entities and biological entity data, said pathart database to store mapped addresses for hierarchically arranged signalling interactions among the biological entities and biological entity data, a processing system including a server module to fetch and/or generate desired pathways dynamically from the stored signalling interactions and biological entities, said processing system to obtain information on the selected biological entities or their interaction