Patents by Inventor Satomi SHIBUMURA

Satomi SHIBUMURA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR PRODUCING CAS3 PROTEINS
    Publication number: 20240141310
    Abstract: The present inventors have found that by cultivating insect cells, into which the Cas3 gene has been introduced, at relatively low temperatures, it is possible to efficiently express recombinant Cas3 proteins with maintained activity, and by purifying the soluble fractions of these cells, it is possible to collect active forms of the recombinant Cas3 proteins in high purity and high yield.
    Type: Application
    Filed: February 25, 2022
    Publication date: May 2, 2024
    Applicants: C4U Corporation, The University of Tokyo, RIKEN
    Inventors: Tomoji MASHIMO, Kazuto YOSHIMI, Kohei TAKESHITA, Masaki YAMAMOTO, Satomi SHIBUMURA
  • METHOD FOR DETECTING SPECIFIC DNA IN SAMPLE
    Publication number: 20230099483
    Abstract: It has been found that by mixing a single-stranded probe DNA whose cleavage can be detected in a reaction system containing a CRISPR-Cas3 system and a sample from which to detect a target DNA, it is possible to detect the target DNA in the sample by using, as indication, a signal generated by the cleavage of the single-stranded probe DNA.
    Type: Application
    Filed: January 25, 2021
    Publication date: March 30, 2023
    Applicants: C4U CORPORATION, OSAKA UNIVERSITY
    Inventors: Tomoji MASHIMO, Kazuto YOSHIMI, Satomi SHIBUMURA