Patents by Inventor Satoru Oka

Satoru Oka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purified mite allergen
    Patent number: 6054125
    Abstract: The present invention is directed to novel purified and isolated mite allergens possessing mite allergen activity with a molecular weight of about 94,000, about 40,000, about 16,000 or about 14,000 as determined by SDS-PAGE, which can be isolated from extracts of mites, and to a process for producing such mites allergens. The purified and isolated mite allergens of the present invention are useful as a pharmaceutical and a diagnostic composition for mite allergic diseases.
    Type: Grant
    Filed: January 20, 1998
    Date of Patent: April 25, 2000
    Assignees: Fumakilla Limited, Hiroshima University
    Inventors: Satoru Oka, Kazuhisa Ono, Seiko Shigeta, Takeshi Wada
  • Low molecular weight allergen obtained from Dermatophagoides farinae
    Patent number: 5773010
    Abstract: New purified mite allergens useful as pharmaceutical and diagnostic compositions for the treatment and diagnosis of mite allergic diseases are provided. Both allergens are contained in fecal extracts of mites in culture. The high molecular weight allergen has a weight average molecular weight of 70,000 to 80,000 as determined by sedimentation equilibrium. This is a glycoprotein containing more than about 70% sugar, and possesses allergen activity. The low molecular weight antigen has a molecular weight of 1,500 to 5,000 as determined by Sephadex G25 gel filtration. This is a glycoprotein containing more than about 40% sugar, and also possesses allergen activity.
    Type: Grant
    Filed: November 29, 1995
    Date of Patent: June 30, 1998
    Assignees: Fumakilla Limited, Hiroshima University
    Inventors: Satoru Oka, Kazuhisa Ono, Seiko Shigeta, Takeshi Wada
  • Purified mite allergen
    Patent number: 5747047
    Abstract: The present invention is directed to novel purified and isolated mite allergens possessing mite allergen activity with a molecular weight of about 94,000, about 40,000, about 16,000 or about 14,000 as determined by SDS-PAGE, which can be isolated from extracts of mite, and to a process for producing such mite allergens. The purified and isolated mites allergens of the present invention are useful as a pharmaceutical and a diagnostic composition for mite allergic diseases.
    Type: Grant
    Filed: August 22, 1994
    Date of Patent: May 5, 1998
    Assignees: Fumakilla Ltd., Hiroshima University
    Inventors: Satoru Oka, Kazuhisa Ono, Seiko Shigeta, Takeshi Wada
  • Purified mite allergen
    Patent number: 5496554
    Abstract: New purified mite allergens useful as pharmaceutical and diagnostic compositions for the treatment and diagnosis of mite allergic diseases are provided. Both allergens are contained in fecal extracts of mites in culture. The high molecular weight allergen has a weight average molecular weight of 70,000 to 80,000 as determined by sedimentation equilibrium. This is a glycoprotein containing more than about 70% sugar, and possesses allergen activity. The low molecular weight antigen has a molecular weight of 1,500 to 5,000 as determined by Sephadex G25 gel filtration. This is a glycoprotein containing more than about 40% sugar, and also possesses allergen activity.
    Type: Grant
    Filed: August 4, 1994
    Date of Patent: March 5, 1996
    Assignees: Fumakilla Limited, Hiroshima University
    Inventors: Satoru Oka, Kazuhisa Ono, Seiko Shigeta, Takeshi Wada
  • DNA encoding the recombinant 40 kDA Dermatophagoides farinae allergen
    Patent number: 5405758
    Abstract: The present invention is directed to a recombinant mite allergen obtainable by expression of a mite-body-derived gene, a gene which codes for said allergen, a mite allergen fragment, a polypeptide having an epitope contained in said allergen, an expression vector capable of expressing the gene, a bacterium, yeast or mammalian cell transformed with said expression vector, a method for producing said allergen, and a pharmaceutical composition or a diagnostic reagent for the treatment of mite allergic diseases.
    Type: Grant
    Filed: December 15, 1993
    Date of Patent: April 11, 1995
    Assignees: Fumakilla Limited, Hiroshima University
    Inventors: Satoru Oka, Kazuhisa Ono, Seiko Shigeta, Takeshi Wada
  • Recombinant 40 KDa Dermatophagoides farinae allergen
    Patent number: 5314991
    Abstract: The present invention is directed to a recombinant mite allergen obtainable by expression of a mite-body-derived gene, a gene which codes for said allergen, a mite allergen fragment, a polypeptide having an epitope contained in said allergen, an expression vector capable of expressing the gene, a bacterium, yeast or mammalian cell transformed with said expression vector, a method for producing said allergen, and a pharmaceutical composition or a diagnostic reagent for the treatment of mite allergic diseases.
    Type: Grant
    Filed: August 22, 1991
    Date of Patent: May 24, 1994
    Assignees: Fumakilla Limited, Hiroshima University
    Inventors: Satoru Oka, Kazuhisa Ono, Seiko Shigeta, Takeshi Wada