Patents by Inventor Satoshi Akahane
Satoshi Akahane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240109512Abstract: A vehicle management apparatus is configured to manage a vehicle for delivery loaded with one or more packages. The vehicle management apparatus includes a controller configured to, upon detecting that the vehicle has stopped, determine, based on vehicle data indicating a status of the vehicle, whether a driver of the vehicle is making a delivery, and control a door of the vehicle to lock in a case in which it has been determined that the driver is making a delivery.Type: ApplicationFiled: September 21, 2023Publication date: April 4, 2024Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Hiroto TOMIDA, Ryosuke KOBAYASHI, Satoshi KOMAMINE, Tetsuya IDE, Mayuko ABE, Makoto AKAHANE, Haruki OGURI
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Publication number: 20240110803Abstract: An information processing apparatus includes a controller configured to extract roads that are difficult for a particular truck to travel based on a travel history of one or more trucks and generate route guidance such that roads that are easy for the particular truck to travel are given priority by avoiding at least one road among the extracted roads.Type: ApplicationFiled: September 22, 2023Publication date: April 4, 2024Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Hiroto TOMIDA, Ryosuke KOBAYASHI, Satoshi KOMAMINE, Tetsuya IDE, Mayuko ABE, Makoto AKAHANE, Haruki OGURI
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Publication number: 20240104488Abstract: A delivery support apparatus according to the present disclosure includes a controller configured to acquire information about a vehicle used for delivery of a package, the information having been acquired on the vehicle, determine, based on the information about the vehicle, a loading/unloading location at which the package was loaded or unloaded, and generate, based on the loading/unloading location, information about a location at which packages can be loaded/unloaded.Type: ApplicationFiled: September 19, 2023Publication date: March 28, 2024Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Hiroto TOMIDA, Ryosuke KOBAYASHI, Satoshi KOMAMINE, Tetsuya IDE, Mayuko ABE, Makoto AKAHANE, Haruki OGURI
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Patent number: 7674938Abstract: The present invention provides compounds represented by general formula (I): or pharmaceutical acceptable salts thereof, wherein R1 and R2 are each hydrogen or lower alkyl; R3, R4, R5 and R6 are each hydrogen, halogen, lower alkyl or lower alkoxy; R7 and R8 are each hydrogen, halogen, lower alkyl, halo-lower alkyl, lower alkoxy, cycloalkyl, aryl, heteroaryl, cyano, a hydroxyl group, lower acyl, carboxy or the like; R9 is —C(O)—R10, -A1-C(O)—R10, —O-A2-C(O)—R10 or a tetrazol-5-yl group, which exhibit potent and selective ?3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.Type: GrantFiled: November 7, 2007Date of Patent: March 9, 2010Assignee: Kissei Pharmaceutical Co., Ltd.Inventors: Junichi Kobayashi, Tetsuya Nakamura, Ritsu Suzuki, Hideyuki Muranaka, Tomonaga Ozawa, Yuichiro Kai, Takehiro Ishikawa, Tatsuhiro Kondo, Tetsuro Tamai, Satoshi Akahane
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Publication number: 20100009939Abstract: The present invention provides a combination drug which is useful for the prevention or treatment of thromboembolism. A pharmaceutical agent comprising an antiplatelet agent in combination with a 5-amidino-2-hydroxybenzenesulfonamide derivative represented by the general formula: wherein R represents a hydrogen atom or a lower alkyl group, and Z represents a hydrogen atom or a hydroxy group, or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: September 16, 2009Publication date: January 14, 2010Applicant: Kissei Pharmaceutical Co., Ltd.Inventors: Yuji HOYANO, Toshiki Honma, Takashi Koizumi, Satoshi Akahane
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Patent number: 7563822Abstract: The present invention relates to an agent for the prevention or treatment of a renal disease comprising as an active ingredient a 5-amidino-2- hydroxybenzenesulfonamide derivative represented by the general formula: wherein R1 is a hydrogen atom or an optionally substituted alkyl group; R2 is a dialkylamino group, an alkyl group, a cycloalkyl group, an optionally substituted aryl group etc.; T is an oxygen atom, a sulfur atom etc.; Q is a hydrogen atom or an optionally substituted alkyl group; and Z is a hydrogen atom, a hydroxy group etc., or a pharmaceutically acceptable salt thereof which has an inhibitory effect on mesangial cell proliferation and a decreasing effect on protein excretion in urine, and are useful for preventing or treating of various renal diseases such as IgA nephropathy, diabetic nephropathy, nephritic syndrome and the like.Type: GrantFiled: March 18, 2003Date of Patent: July 21, 2009Assignee: Kissei Pharmaceutical Co., Ltd.Inventors: Takashi Koizumi, Yuji Hoyano, Satoshi Akahane
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Patent number: 7446128Abstract: A compound which can be used as an agent for treating interstitial cystitis. An agent for treating interstitial cystitis, which comprises a phenoxyacetic acid derivative represented by a general formula (I) wherein R1 represents hydroxyl group or a lower alkoxy group, or a pharmacologically acceptable salt thereof. Since the phenoxyacetic acid derivative represented by the general formula (I) or a pharmacologically acceptable salt thereof or a hydrate or solvate thereof has a selective ?3-adrenoceptor stimulating activity and a remarkable action to inhibit a capsaicin-sensitive sensory nerve, it can be used as a preventive or therapeutic agent for interstitial cystitis and hyperactive bladder which are accompanied by pain, other diseases in which the capsaicin-sensitive sensory nerve is concerned (e.g., acute or chronic and systemic or topical pain and inflammation) and irritable bowel syndrome (IBS) and the like.Type: GrantFiled: November 7, 2005Date of Patent: November 4, 2008Assignee: Kissei Pharmaceutical Co., Ltd.Inventors: Kouichi Kaidoh, Satoshi Akahane
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Publication number: 20080249177Abstract: The present invention provides compounds represented by general formula (I): or pharmaceutical acceptable salts thereof, wherein R1 and R2 are each hydrogen or lower alkyl; R3, R4, R5 and R6 are each hydrogen, halogen, lower alkyl or lower alkoxy; R7 and R8 are each hydrogen, halogen, lower alkyl, halo-lower alkyl, lower alkoxy, cycloalkyl, aryl, heteroaryl, cyano, a hydroxyl group, lower acyl, carboxy or the like; R9 is —C(O)—R10, -A1-C(O)—R10, —O-A2-C(O)—R10 or a tetrazol-5-yl group, which exhibit potent and selective ?3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.Type: ApplicationFiled: November 7, 2007Publication date: October 9, 2008Inventors: Junichi KOBAYASHI, Tetsuya Nakamura, Ritsu Suzuki, Hideyuki Muranaka, Tomonaga Ozawa, Yuichiro Kai, Takehiro Ishikawa, Tatsuhiro Kondo, Tetsuro Tamai, Satoshi Akahane
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Patent number: 7423185Abstract: The present invention provides compounds represented by general formula (I): or pharmaceutical acceptable salts thereof, wherein R1 and R2 are each hydrogen or lower alkyl; R3, R4, R5 and R6 are each hydrogen, halogen, lower alkyl or lower alkoxy; R7 and R8 are each hydrogen, halogen, lower alkyl, halo-lower alkyl, lower alkoxy, cycloalkyl, aryl, heteroaryl, cyano, a hydroxyl group, lower acyl, carboxy or the like; R9 is —C(O)—R10, -A1-C(O)—R10, —O-A2-C(O)—R10 or a tetrazol-5-yl group, which exhibit potent and selective ?3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.Type: GrantFiled: January 30, 2004Date of Patent: September 9, 2008Assignee: Kissei Pharmaceutical Co., Ltd.Inventors: Junichi Kobayashi, Tetsuya Nakamura, Ritsu Suzuki, Hideyuki Muranaka, Tomonaga Ozawa, Yuichiro Kai, Takehiro Ishikawa, Tatsuhiro Kondo, Tetsuro Tamai, Satoshi Akahane
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Patent number: 7417169Abstract: The present invention provides compounds represented by general formula (I): a prodrug thereof, or pharmaceutical acceptable salts thereof, wherein R1 is hydrogen or lower alkyl; each of R2 and R3 is independently hydrogen or lower alkyl; each of R4, R5 and R6 is independently hydrogen, halogen, lower alkyl or lower alkoxy; R7 is hydrogen or lower alkyl; R8 is hydrogen, halogen, lower alkyl, lower alkoxy, etc; R9 is —COR10, -A1-COR10, —O-A2-COR10, etc; Ar is optionally substituted phenyl or heteroaryl; and A is a bond, —OCH2—, etc, which exhibit potent and selective ?3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.Type: GrantFiled: October 5, 2004Date of Patent: August 26, 2008Assignee: Kissei Pharmaceutical Co., Ltd.Inventors: Junichi Kobayashi, Tetsuya Nakamura, Hideyuki Muranaka, Takehiro Ishikawa, Tetsuro Tamai, Satoshi Akahane
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Patent number: 7402692Abstract: The present invention provides novel intermediates represented by general formula (I) etc. for preparing a phenoxyacetic acid derivative represented by general formula (X) or a pharmaceutically acceptable salt thereof, which has ?3-adrenoceptor stimulating activity and are useful for treating or preventing obesity, hyperglycemia, diseases caused by intestinal hypermotility, pollakiuria, urinary incontinence, depression or biliary calculus.Type: GrantFiled: October 24, 2007Date of Patent: July 22, 2008Assignee: Kissei Pharmaceutical Co., Ltd.Inventors: Nobuyuki Tanaka, Tetsuro Tamai, Harunobu Mukaiyama, Takehiro Ishikawa, Junichi Kobayashi, Satoshi Akahane, Hiromu Harada
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Patent number: 7396954Abstract: The present invention provides novel intermediates represented by general formula (I) etc. for preparing a phenoxyacetic acid derivative represented by general formula (X) or a pharmaceutically acceptable salt thereof, which has ?3-adrenoceptor stimulating activity and are useful for treating or preventing obesity, hyperglycemia, diseases caused by intestinal hypermotility, pollakiuria, urinary incontinence, depression or biliary calculus.Type: GrantFiled: October 24, 2007Date of Patent: July 8, 2008Assignee: Kissei Pharmaceutical Co., Ltd.Inventors: Nobuyuki Tanaka, Tetsuro Tamai, Harunobu Mukaiyama, Takehiro Ishikawa, Junichi Kobayashi, Satoshi Akahane, Hiromu Harada
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Patent number: 7393968Abstract: The present invention provides novel intermediates represented by general formula (I) etc. for preparing a phenoxyacetic acid derivative represented by general formula (X) or a pharmaceutically acceptable salt thereof, which has ?3-adrenoceptor stimulating activity and are useful for treating or preventing obesity, hyperglycemia, diseases caused by intestinal hypermotility, pollakiuria, urinary incontinence, depression or biliary calculus.Type: GrantFiled: October 24, 2007Date of Patent: July 1, 2008Assignee: Kissei Pharmaceutical Co., Ltd.Inventors: Nobuyuki Tanaka, Tetsuro Tamai, Harunobu Mukaiyama, Takehiro Ishikawa, Junichi Kobayashi, Satoshi Akahane, Hiromu Harada
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Publication number: 20080045741Abstract: The present invention provides novel intermediates represented by general formula (I) etc. for preparing a phenoxyacetic acid derivative represented by general formula (X) or a pharmaceutically acceptable salt thereof, which has ?3-adrenoceptor stimulating activity and are useful for treating or preventing obesity, hyperglycemia, diseases caused by intestinal hypermotility, pollakiuria, urinary incontinence, depression or biliary calculus. The present invention also provides a process for preparing said intermediates and a method of using said intermediates.Type: ApplicationFiled: October 24, 2007Publication date: February 21, 2008Applicant: KISSEI PHARMACEUTICAL CO., LTD.Inventors: Nobuyuki Tanaka, Tetsuro Tamai, Harunobu Mukaiyama, Takehiro Ishikawa, Junichi Kobayashi, Satoshi Akahane, Hiromu Harada
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Publication number: 20080045739Abstract: The present invention provides novel intermediates represented by general formula (I) etc. for preparing a phenoxyacetic acid derivative represented by general formula (X) or a pharmaceutically acceptable salt thereof, which has ?3-adrenoceptor stimulating activity and are useful for treating or preventing obesity, hyperglycemia, diseases caused by intestinal hypermotility, pollakiuria, urinary incontinence, depression or biliary calculus. The present invention also provides a process for preparing said intermediates and a method of using said intermediates.Type: ApplicationFiled: October 24, 2007Publication date: February 21, 2008Applicant: KISSEI PHARMACEUTICAL CO., LTDInventors: Nobuyuki Tanaka, Tetsuro Tamai, Harunobu Mukaiyama, Takehiro Ishikawa, Junichi Kobayashi, Satoshi Akahane, Hiromu Harada
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Publication number: 20080045740Abstract: The present invention provides novel intermediates represented by general formula (I) etc. for preparing a phenoxyacetic acid derivative represented by general formula (X) or a pharmaceutically acceptable salt thereof, which has ?3-adrenoceptor stimulating activity and are useful for treating or preventing obesity, hyperglycemia, diseases caused by intestinal hypermotility, pollakiuria, urinary incontinence, depression or biliary calculus. The present invention also provides a process for preparing said intermediates and a method of using said intermediates.Type: ApplicationFiled: October 24, 2007Publication date: February 21, 2008Applicant: KISSEI PHARMACEUTICAL CO., LTD.Inventors: Nobuyuki TANAKA, Tetsuro Tamai, Harunobu Mukaiyama, Takehiro Ishikawa, Junichi Kobayashi, Satoshi Akahane, Hiromu Harada
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Patent number: 7329771Abstract: The present invention provides novel intermediates represented by general formula (I) etc. for preparing a phenoxyacetic acid derivative represented by general formula (X) or a pharmaceutically acceptable salt thereof, which has ?3-adrenoceptor stimulating activity and are useful for treating or preventing obesity, hyperglycemia, diseases caused by intestinal hypermotility, pollakiuria, urinary incontinence, depression or biliary calculus. The present invention also provides a process for preparing said intermediates and a method of using said intermediates.Type: GrantFiled: September 5, 2002Date of Patent: February 12, 2008Assignee: Kissei Pharmaceuticals Co., Ltd.Inventors: Nobuyuki Tanaka, Tetsuro Tamai, Harunobu Mukaiyama, Takehiro Ishikawa, Junichi Kobayashi, Satoshi Akahane, Hiromu Harada
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Patent number: 7256215Abstract: The present invention provides a novel crystalline form of n-butyl[4-[2-[2-hydroxy-5-(N-hydroxycarbamimidoyl) benzenesulfonylamino]ethyl]-2?-methanesulfonyl-3-yloxy] acetate hydrochloride, pharmaceutical compositions containing the same and their uses, which exhibits excellent inhibitory activities against activated blood coagulation factor X, and is useful for the treatment or prevention of a tromboembolic disease.Type: GrantFiled: March 4, 2003Date of Patent: August 14, 2007Assignee: Kissei Pharmaceutical Co., Ltd.Inventors: Harunobu Mukaiyama, Yuichiro Kai, Hideki Takeuchi, Kenji Yokoyama, Yoshihiro Terao, Satoshi Akahane
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Patent number: 7208520Abstract: The present invention provides ethyl (?)-2-[4-[2-[[(1S,2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-2,5-dimethylphenoxy]acetate hydrochloride, crystalline forms thereof and pharmaceutical compositions containing them, which have excellent ?3-adrenoceptor stimulating effects, therapeutic effects on pollakiuria or urinary incontinence and storage stabilities and are useful as a medicament.Type: GrantFiled: August 27, 2002Date of Patent: April 24, 2007Assignee: Kissei Pharmaceutical Co., Ltd.Inventors: Hidetoshi Isawa, Yukihiko Hotei, Kiyoshi Kasai, Junichi Sonehara, Satoshi Akahane, Hiromu Harada
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Publication number: 20070078184Abstract: The present invention provides compounds represented by general formula (I): a prodrug thereof, or pharmaceutical acceptable salts thereof, wherein R1 is hydrogen or lower alkyl; each of R2 and R3 is independently hydrogen or lower alkyl; each of R4, R5 and R6 is independently hydrogen, halogen, lower alkyl or lower alkoxy; R7 is hydrogen or lower alkyl; R8 is hydrogen, halogen, lower alkyl, lower alkoxy, etc; R9 is —COR10, -A1-COR10, —O-A2-COR10, etc; Ar is optionally substituted phenyl or heteroaryl; and A is a bond, —OCH2—, etc, which exhibit potent and selective ?3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.Type: ApplicationFiled: October 5, 2004Publication date: April 5, 2007Inventors: Junichi Kobayashi, Tetsuya Nakamura, Hideyuki Muranaka, Takehiro Ishikawa, Tetsuro Tamai, Satoshi Akahane