Abstract: A target substance detection method includes forming a complex by causing a target substance and a dielectric particle to bind to each other, the dielectric particle being modified with a substance (for example, an antibody) having a property of specifically binding to the target substance; subjecting a bound particle and an unbound particle to dielectrophoresis in a liquid, the bound particle being the dielectric particle constituting the complex, the unbound particle being a dielectric particle not constituting the complex; and detecting the target substance in the complex, based on a difference in motion between the bound particle and the unbound particle caused by the dielectrophoresis.

Abstract: In a detection method, first dielectric particles each capable of being bound to a first target substance and second dielectric particles each capable of being bound to a second target substance are caused to react with a sample that contains a first target substance and a second target substance, the second dielectric particles having a different dielectrophoretic property from the first dielectric particles, a first composite particle to which the first target substance is bound is separated from the other first dielectric particle, and a second composite particle to which the second target substance is bound is separated from the other second dielectric particle by causing dielectrophoresis in the sample after the reaction, and the first target substance contained in the separated first composite particle and the second target substance contained in the second composite particle are each detected.

Abstract: A counting method includes aggregating particles in a sample by the action of first dielectrophoretic force, dispersing the aggregated particles by the action of second dielectrophoretic force, which is different from the first dielectrophoretic force, capturing a dispersion image including the dispersed particles, and determining the number of particles on the basis of the dispersion image.

Abstract: A counting method includes aggregating particles in a sample by action of first-direction dielectrophoretic force, dispersing the aggregated particles by action of second-direction dielectrophoretic force, which is different from the first-direction dielectrophoretic force, capturing a dispersion image including the dispersed particles, and determining the number of particles on the basis of the dispersion image.

Abstract: A detection method includes forming a complex by binding a target substance and a dielectric particle modified by a single-domain antibody that is bindable to the target substance, separating the complex and an unbound particle in a fluid with dielectrophoresis, the unbound particle being the dielectric particle not forming the complex, and detecting the target substance contained in the separated complex with an imaging element.

Abstract: A target substance detection method includes forming a complex by causing a target substance and a dielectric particle to bind to each other, the dielectric particle being modified with a substance (for example, an antibody) having a property of specifically binding to the target substance; subjecting a bound particle and an unbound particle to dielectrophoresis in a liquid, the bound particle being the dielectric particle constituting the complex, the unbound particle being a dielectric particle not constituting the complex; and detecting the target substance in the complex, based on a difference in motion between the bound particle and the unbound particle caused by the dielectrophoresis.

Abstract: A target substance detection method includes forming a complex by causing a target substance and a dielectric particle to bind to each other, the dielectric particle being modified with a substance having a property of specifically binding to the target substance; separating the complex and an unbound particle from each other in a liquid by dielectrophoresis, the unbound particle being a dielectric particle not constituting the complex; and detecting the target substance included in the separated complex by using an imaging element.

Abstract: A biometric apparatus includes a light source, an image sensor, a control circuit, and a signal processing circuit. The control circuit causes a light source to repeatedly emit a light pulse radiated onto a target part including a head of a target, causes an image sensor to receive a reflected light pulse which is caused as the light pulse is radiated onto the target part, causes the image sensor to output first image data indicating appearance of a face of the target, and causes the image sensor to output second image data according to distribution of an amount of light of at least one of components of the reflected light pulse. The signal processing circuit generates data indicating a state of the target based on a temporal change in the first image data and a temporal change in the second image data and outputs the data.

Abstract: The present invention provides a cocaine aptamer represented by at least one selected from the group consisting of the following chemical formula (CI) and the following chemical formula (CII), 5?-R-DNA-L-Fc-3???(CI) 5?-Fc-L-DNA-R-3???(CII) where R is selected from the group consisting of a hydrocarbon group and the derivative thereof; DNA consists of a gene sequence capable of binding to cocaine; L is absent or an optional linker; and Fc represents a ferrocene group. The above-identified cocaine aptamer is used to detect cocaine with high sensitivity.

Abstract: The present invention provides a cocaine aptamer represented by the following chemical formula (Cl), R-DNA-L-Fc??(Cl) where R is selected from the group consisting of a hydrocarbon group and the derivative thereof; DNA consists of a gene sequence capable of binding to cocaine; L is a linker represented by ((CH2)2—O)n1—PO4—(CH2)n2-L1; L1 is absent or an optional linker; n1 represents a natural number; n2 represents a natural number; and Fc represents a ferrocene group. The cocaine aptamer is capable of detecting cocaine with high sensitivity.

Abstract: The present invention provides a cocaine aptamer represented by the following chemical formula (CI), R-DNA-L-Fc??(CI) where R represents R1-PO4—(CH2)n1—; R1 is selected from the group consisting of a hydrocarbon group and the derivative thereof; n1 represents a natural number; DNA consists of a gene sequence capable of binding to cocaine; L is a linker represented by -L1-(CH2)n2-L2-; L1 is absent or an optional linker; L2 is absent or an optional linker; n2 represents a natural number; and Fc represents a ferrocene group. The present invention provides a cocaine aptamer capable of detecting cocaine with high sensitivity.

Abstract: The present invention provides a cocaine aptamer represented by at least one selected from the group consisting of the following chemical formula (CI) and the following chemical formula (CII), 5?-R-DNA-L-Fc-3???(CI) 5?-Fc-L-DNA-R-3???(CII) where R is selected from the group consisting of a hydrocarbon group and the derivative thereof; DNA consists of a gene sequence capable of binding to cocaine; L is absent or an optional linker; and Fc represents a ferrocene group. The above-identified cocaine aptamer is used to detect cocaine with high sensitivity.

Abstract: The present invention provides a cocaine aptamer represented by the following chemical formula (CI), R-DNA-L-Fc??(CI) where R represents R1-PO4—(CH2)n1—; R1 is selected from the group consisting of a hydrocarbon group and the derivative thereof; n1 represents a natural number; DNA consists of a gene sequence capable of binding to cocaine; L is a linker represented by -L1-(CH2)n2-L2-; L1 is absent or an optional linker; L2 is absent or an optional linker; n2 represents a natural number; and Fc represents a ferrocene group. The present invention provides a cocaine aptamer capable of detecting cocaine with high sensitivity.

Abstract: The present invention provides a cocaine aptamer represented by the following chemical formula (Cl), R-DNA-L-Fc??(Cl) where R is selected from the group consisting of a hydrocarbon group and the derivative thereof; DNA consists of a gene sequence capable of binding to cocaine; L is a linker represented by ((CH2)2—O)n1—PO4—(CH2)n2-L1; L1 is absent or an optional linker; n1 represents a natural number; n2 represents a natural number; and Fc represents a ferrocene group. The cocaine aptamer is capable of detecting cocaine with high sensitivity.

Abstract: The present invention provides an electrostatic atomizer comprising: a container having an inlet; an atomization electrode having one end projecting in the container; an opposite electrode provided in the container; a tubular collection electrode provided opposite to the atomization electrode; a mask surrounding an outer periphery of the tubular collection electrode; and a cooling part for cooling the tubular collection electrode. The opposite electrode is provided between the atomization electrode and the tubular collection electrode. The mask is formed of resin. The mask comprises a mask through-hole. The tubular collection electrode is inserted in the mask through-hole. One end of the tubular collection electrode is located in the mask through-hole. The present invention provides a method for efficiently obtaining a liquid sample from a gaseous sample and an electrostatic atomizer suitable for the method.

Abstract: An electrochemical detector is an electrochemical detector for detecting a substance in a liquid by generating a redox cycle, the electrochemical detector comprising: a first working electrode having a first electrode surface, a second working electrode having a second electrode surface, and a plurality of insulating spacer particles, wherein the first and second electrode surfaces are placed so as to face each other so that an electric field is formed between the first and second electrode surfaces, and the plurality of spacer particles are placed along the first and second electrode surfaces so as to separate the first and second electrode surfaces from each other.

Abstract: The present invention provides an electrostatic atomizer comprising: a container having an inlet; an atomization electrode having one end projecting in the container; an opposite electrode provided in the container; a tubular collection electrode provided opposite to the atomization electrode; a mask surrounding an outer periphery of the tubular collection electrode; and a cooling part for cooling the tubular collection electrode. The opposite electrode is provided between the atomization electrode and the tubular collection electrode. The mask is formed of resin. The mask comprises a mask through-hole. The tubular collection electrode is inserted in the mask through-hole. One end of the tubular collection electrode is located in the mask through-hole. The present invention provides a method for efficiently obtaining a liquid sample from a gaseous sample and an electrostatic atomizer suitable for the method.

Abstract: Provided is a method for accurately quantifying a chemical substance contained in a sample solution at a significantly low concentration of not more than 1×10?8M. A measurement system used for the method includes a counter electrode 13, a first reference electrode 12, a first working electrode 11a, a second working electrode 11b, a second reference electrode 14 and a gel-coated electrode 15. The gel-coated electrode 15 is electrically equivalent to the second working electrode 11b. The gel-coated electrode 15 comprises an electrode body 31 and a gel 34. The surface of the electrode body 31 is coated with the gel 34. The gel 34 contains a standard electrolyte and an ionic liquid. The gel 34 contains no water. The ionic liquid is hydrophobic and nonvolatile. The ionic liquid is composed of a cation and an anion. The standard electrolyte is composed of the cation and a halide ion.

Abstract: Provided is a method for accurately quantifying a chemical substance contained in a sample solution at a significantly low concentration of not more than 1×10?8M. First, prepared is a measurement system including a counter electrode 13, a first reference electrode 12, a first working electrode 11a, a second working electrode 11b and a second reference electrode 14. Second, voltages of V1 volts and V2 volts (V1>V2) are applied to the first working electrode 11a and the second working electrode 11b, respectively. Third, a voltage difference ?E between the second working electrode 11b and the second reference electrode 14 is measured. Finally, the concentration of the chemical substance is calculated on the basis of the voltage difference ?E.

Abstract: An electrochemical detector is an electrochemical detector for detecting a substance in a liquid by generating a redox cycle, the electrochemical detector comprising: a first working electrode having a first electrode surface, a second working electrode having a second electrode surface, and a plurality of insulating spacer particles, wherein the first and second electrode surfaces are placed so as to face each other so that an electric field is formed between the first and second electrode surfaces, and the plurality of spacer particles are placed along the first and second electrode surfaces so as to separate the first and second electrode surfaces from each other.