Abstract: A water treatment apparatus is provided with: a treatment vessel into which a solution of interest S is fed; a hollow fiber membrane which is immersed in the solution of interest S in the treatment vessel and has gas permeability; and a biological membrane which is formed on the outer surface of the hollow fiber membrane and utilizes oxygen-containing air fed into the hollow fiber membrane. In the water treatment apparatus, the solution of interest S is treated with the biological membrane. The water treatment apparatus is also provided with a gas-diffusing tube which is located below the hollow fiber membrane and ejects a washing gas to wash the biological membrane; and an oxygen concentration meter which measures the oxygen concentration in discharged air that has passed through the hollow fiber membrane.

Abstract: The present invention relates to an improved method for determining nucleotide sequences or nucleotide sequences on biochips/micro-assays, for example, using p53 mediated hybridization. The present invention relates particularly to the use of p53 polypeptides in determining changes in nucleotide sequences.

Abstract: A biological molecule biochip that supports biological molecules between a first member and a second member; in either the first member or the second member, by forming a plurality of grooves in parallel in a face that makes contact with the other member, a plurality of spaces are provided that become reaction regions.

Abstract: The present invention relates to an improved method for determining nucleotide sequences or nucleotide sequences on biochips/micro-assays, for example, using p53 mediated hybridization. The present invention relates particularly to the use of p53 polypeptides in determining changes in nucleotide sequences.