Patents by Inventor Satoshi Gojo
Satoshi Gojo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240115652Abstract: There is provided a bioabsorbable peptide tissue occluding agent that can be applied to large mammals including humans, the peptide tissue occluding agent being obtained by artificial synthesis to avoid concerns of infection by viruses and the like. The tissue occluding agent contains a peptide, wherein the peptide is an amphiphilic peptide having 8-200 amino acid residues with the hydrophilic amino acids and hydrophobic amino acids alternately bonded, and is a self-assembling peptide exhibiting a ?-structure in aqueous solution in the presence of physiological pH and/or a cation.Type: ApplicationFiled: September 13, 2023Publication date: April 11, 2024Inventors: Kentaro Takamura, Satoshi Gojo, Satoru Kobayashi
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Patent number: 11801281Abstract: There is provided a bioabsorbable peptide tissue occluding agent that can be applied to large mammals including humans, the peptide tissue occluding agent being obtained by artificial synthesis to avoid concerns of infection by viruses and the like. The tissue occluding agent contains a peptide, wherein the peptide is an amphiphilic peptide having 8-200 amino acid residues with the hydrophilic amino acids and hydrophobic amino acids alternately bonded, and is a self-assembling peptide exhibiting a ?-structure in aqueous solution in the presence of physiological pH and/or a cation.Type: GrantFiled: January 4, 2022Date of Patent: October 31, 2023Assignee: 3-D Matrix, Ltd.Inventors: Kentaro Takamura, Satoshi Gojo, Satoru Kobayashi
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Publication number: 20220403002Abstract: Provided are a B-cell antibody receptor (BAR), a BAR-T cell and others which are effective for the treatment of diseases associated with antibodies produced in the bodies of patients. The B-cell antibody receptor (BAR) according to the present invention comprises (a) an antibody binding domain, (b) a transmembrane domain, (c) an intracellular domain of a costimulating factor and (d) an intracellular domain of an activated receptor which are linked together.Type: ApplicationFiled: October 28, 2020Publication date: December 22, 2022Inventors: Satoshi GOJO, Daisuke KAMI, Atsushi HOSHINO, Yoshito MINAMI, Akira SHIKUMA
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Publication number: 20220193184Abstract: There is provided a bioabsorbable peptide tissue occluding agent that can be applied to large mammals including humans, the peptide tissue occluding agent being obtained by artificial synthesis to avoid concerns of infection by viruses and the like. The tissue occluding agent contains a peptide, wherein the peptide is an amphiphilic peptide having 8-200 amino acid residues with the hydrophilic amino acids and hydrophobic amino acids alternately bonded, and is a self-assembling peptide exhibiting a ?-structure in aqueous solution in the presence of physiological pH and/or a cation.Type: ApplicationFiled: January 4, 2022Publication date: June 23, 2022Inventors: Kentaro Takamura, Satoshi Gojo, Satoru Kobayashi
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Publication number: 20210123104Abstract: The present disclosure provides methods for detecting macro-heteroplasmy and/or micro-heteroplasmy in mitochondrial DNA. The methods can include detecting or monitoring the presence of heteroplasmy, and/or identifying a threshold level of heteroplasmy. In addition, the methods can be used for diagnosing a mitochondrial related disease or disorder, as well as for monitoring the efficacy of a therapy affecting mitochondrial DNA (mtDNA) in a subject having or suspected of having heteroplasmy.Type: ApplicationFiled: October 23, 2020Publication date: April 29, 2021Inventors: Ryotaro Maeda, Daisuke Kami, Satoshi Gojo
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Publication number: 20210032585Abstract: It is solved by the rod-shaped tubular cell structure maintaining support device for cultivating a tubular cell structure including a hollow portion inside for a predetermined period of time while maintaining the hollow portion, the tubular cell structure maintaining support device including an outer diameter insertable into the hollow portion of the cell structure, and when inserted into the hollow portion, capable of allowing the tubular cell structure maintaining support device to adhere to an inner surface of the cell structure, and a penetration conduit including openings at both ends of the tubular cell structure maintaining support device, and penetrating between the openings, wherein the tubular cell structure maintaining support device has an oxygen permeable structure from the penetration conduit to an outer surface of the tubular cell structure maintaining support device.Type: ApplicationFiled: April 9, 2018Publication date: February 4, 2021Applicant: CYFUSE BIOMEDICAL K.K.Inventors: Satoshi GOJO, Daisuke KAMI, Kumika MATSUBAYASHI, Shizuka AKIEDA
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Publication number: 20200222496Abstract: There is provided a bioabsorbable peptide tissue occluding agent that can be applied to large mammals including humans, the peptide tissue occluding agent being obtained by artificial synthesis to avoid concerns of infection by viruses and the like. The tissue occluding agent contains a peptide, wherein the peptide is an amphiphilic peptide having 8-200 amino acid residues with the hydrophilic amino acids and hydrophobic amino acids alternately bonded, and is a self-assembling peptide exhibiting a ?-structure in aqueous solution in the presence of physiological pH and/or a cation.Type: ApplicationFiled: January 15, 2020Publication date: July 16, 2020Inventors: Kentaro Takamura, Satoshi Gojo, Satoru Kobayashi
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Publication number: 20200199178Abstract: An object of the present invention is to provide an excellent treatment agent for a lysosomal storage disease. According to the present invention, there is provided a treatment agent for a lysosomal storage disease including a cell structure which includes a plurality of biocompatible polymer blocks and a plurality of cells of at least one type and in which at least one of the polymer blocks is disposed in gaps between the plurality of cells.Type: ApplicationFiled: December 27, 2019Publication date: June 25, 2020Applicants: FUJIFILM Corporation, KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATIONInventors: Kentaro NAKAMURA, Tsukasa KITAHASHI, Rie HANDO, Satoshi GOJO, Daisuke KAMI
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Patent number: 10596225Abstract: There is provided a bioabsorbable peptide tissue occluding agent that can be applied to large mammals including humans, the peptide tissue occluding agent being obtained by artificial synthesis to avoid concerns of infection by viruses and the like. The tissue occluding agent contains a peptide, wherein the peptide is an amphiphilic peptide having 8-200 amino acid residues with the hydrophilic amino acids and hydrophobic amino acids alternately bonded, and is a self-assembling peptide exhibiting a ?-structure in aqueous solution in the presence of physiological pH and/or a cation.Type: GrantFiled: October 4, 2013Date of Patent: March 24, 2020Assignee: 3-D Matrix, Ltd.Inventors: Kentaro Takamura, Satoshi Gojo, Satoru Kobayashi
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Patent number: 10576123Abstract: There is provided a bioabsorbable peptide tissue occluding agent that can be applied to large mammals including humans, the peptide tissue occluding agent being obtained by artificial synthesis to avoid concerns of infection by viruses and the like. The tissue occluding agent contains a peptide, wherein the peptide is an amphiphilic peptide having 8-200 amino acid residues with the hydrophilic amino acids and hydrophobic amino acids alternately bonded, and is a self-assembling peptide exhibiting a ?-structure in aqueous solution in the presence of physiological pH and/or a cation.Type: GrantFiled: October 6, 2009Date of Patent: March 3, 2020Assignee: 3-D Matrix, Ltd.Inventors: Kentaro Takamura, Satoshi Gojo, Satoru Kobayashi
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Publication number: 20200054682Abstract: The present invention provides methods and compositions for generation of mitochondria replaced cells (MirC), and therapeutic methods for using such compositions for treating a subject having an age-related disease or syndrome, mitochondrial disease or disorder, or otherwise in need of mitochondrial replacement. Also provided are methods and compositions for producing a recipient cell having a mitochondrial disease or disorder, as well as methods and compositions for producing or enhancing production of an inducible pluripotent stem cell (iPSC). In addition, methods and compositions to enhance mitochondrial transfer are also included.Type: ApplicationFiled: August 13, 2019Publication date: February 20, 2020Inventors: Satoshi GOJO, Daisuke KAMI, Hideki MAEDA
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Publication number: 20200032183Abstract: An object of the present invention is to provide a method of manufacturing a large number of uniform cell structures for a short period of time. According to the present invention, provided is a method of manufacturing a cell structure, including: a step of adding a mixture of biocompatible macromolecular blocks, cells, and a liquid medium to a first culture container having a culture surface on which the plurality of recessed portions are formed and a side wall part standing on an outer periphery of the culture surface such that a liquid surface of the mixture is over the culture surface; a step of allowing a first culture container to stand and forming a cell structure in the recessed portion; and a step of stirring and culturing a content of the first culture container in a second culture container including stirring means.Type: ApplicationFiled: September 17, 2019Publication date: January 30, 2020Applicants: FUJIFILM Corporation, KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATIONInventors: Kentaro NAKAMURA, Rie HANDO, Satoshi GOJO, Daisuke KAMI
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Publication number: 20140038909Abstract: There is provided a bioabsorbable peptide tissue occluding agent that can be applied to large mammals including humans, the peptide tissue occluding agent being obtained by artificial synthesis to avoid concerns of infection by viruses and the like. The tissue occluding agent contains a peptide, wherein the peptide is an amphiphilic peptide having 8-200 amino acid residues with the hydrophilic amino acids and hydrophobic amino acids alternately bonded, and is a self-assembling peptide exhibiting a ?-structure in aqueous solution in the presence of physiological pH and/or a cation.Type: ApplicationFiled: October 4, 2013Publication date: February 6, 2014Applicant: 3-D MATRIX, LTD.Inventors: Kentaro TAKAMURA, Satoshi GOJO, Satoru KOBAYASHI
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Publication number: 20110201541Abstract: There is provided a bioabsorbable peptide tissue occluding agent that can be applied to large mammals including humans, the peptide tissue occluding agent being obtained by artificial synthesis to avoid concerns of infection by viruses and the like. The tissue occluding agent contains a peptide, wherein the peptide is an amphiphilic peptide having 8-200 amino acid residues with the hydrophilic amino acids and hydrophobic amino acids alternately bonded, and is a self-assembling peptide exhibiting a ?-structure in aqueous solution in the presence of physiological pH and/or a cation.Type: ApplicationFiled: October 6, 2009Publication date: August 18, 2011Applicant: 3-D MATRIX, LTD.Inventors: Kentaro Takamura, Satoshi Gojo, Satoru Kobayashi
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Publication number: 20020142457Abstract: The present invention relates to methods for isolation, purification, expansion, and differentiation of cells having the potential to differentiate into cardiomyocytes. Furthermore, the present invention relates to methods for proliferating cells having the potential to differentiate into cardiomyocytes and for regulating their differentiation into cardiomyocytes using various cytokines and transcription factors. Moreover, the present invention relates to a method for obtaining surface antigens specific for cells having the potential to differentiate into cardiomyocytes, a method for obtaining genes encoding the surface antigens, a method for obtaining antibodies specific for the surface antigens, and a method for obtaining a protein and a gene controlling the proliferation of cells having the potential to differentiation into cardiomyocytes and their differentiation into cardiomyocytes.Type: ApplicationFiled: December 28, 2000Publication date: October 3, 2002Inventors: Akihiro Umezawa, Jun-Ichi Hata, Keiichi Fukuda, Satoshi Ogawa, Kazuhiro Sakurada, Satoshi Gojo, Yoji Yamada