Abstract: The present invention relates to a novel peptide having a specified amino acid sequence or its derivative, or a salt thereof. Further, the present invention relates to a composition containing the novel peptide or the like, a method of utilizing the novel peptide or the like, use of the novel peptide or the like, a polynucleotide encoding the novel peptide, or the like. The novel peptide of the present invention or its derivative, or a salt thereof can be utilized for enhancing production of at least one member selected from the group consisting of collagen and hyaluronic acid in a cell.

Abstract: The present invention relates to a novel peptide having a specified amino acid sequence or its derivative, or a salt thereof. Further, the present invention relates to a composition containing the novel peptide or the like, a method of utilizing the novel peptide or the like, use of the novel peptide or the like, a polynucleotide encoding the novel peptide, or the like. The novel peptide of the present invention or its derivative, or a salt thereof can be utilized for enhancing production of at least one member selected from the group consisting of collagen and hyaluronic acid in a cell.

Abstract: The present invention has as an object to provide a preparation for external use on skin in which a water-soluble ascorbic acid can be stably dissolved. By blending a low molecular weight betaine in a preparation for external use on skin including a water-soluble ascorbic acid and a glycol ether or a specific polyhydric alcohol, the water-soluble ascorbic acid can be stably dissolved. For this reason, a preparation for external use on skin in which a water-soluble ascorbic acid can be blended in a high concentration can be produced, and therefore, the various effects which ascorbic acid inherently possesses can be effectively exhibited depending on the blending amount thereof. In addition, a preparation which does not give a sticky sensation after applying to the skin, provides a moisturizing sensation, and provides good fitness to the skin, can be produced.

Abstract: The present invention has as an object to provide a composition for external use on skin whose percutaneous absorption of an active component is increased, whereby a large amount of the active component can be delivered into the skin. By employing diglycerol and a low molecular weight betaine together, a percutaneous absorption accelerator excellent in permeability of an active component is provided. According to the percutaneous absorption accelerator of the present invention, the accelerated percutaneous absorption amount of an active component is greatly increased, whereby an effect which the active component essentially possesses is sufficiently exhibited.

Abstract: The present invention has as an object to provide a preparation for external use on skin in which the percutaneous absorption amount of ascorbic acid or an ascorbic acid derivative is increased and an effect on improving skin pigmentation and dullness is enhanced. In a preparation for external use on skin, comprising one or more compounds selected from ascorbic acid and ascorbic acid derivatives, by employing diglycerol and a low molecular weight betaine together, a preparation for external use on skin in which the percutaneous absorption of the ascorbic acid or the ascorbic acid derivative is increased, an effect on improving skin pigmentation and dullness, etc. is sufficiently exhibited and an excellent humectant effect is exhibited can be provided.