Abstract: The present disclosure relates to methods for treatment of mucopolysaccharidosis type I in a subject in need thereof by administering a pharmaceutical composition containing a fusion protein of an anti-human transferrin receptor antibody and human ?-L-iduronidase.

Abstract: A control device includes: a monitoring unit that monitors a storage amount and a temperature of a battery that supplies electric power for executing a software update process; a determination unit that determines whether or not the storage amount of the battery is equal to or greater than the first storage amount and whether or not the temperature of the battery is equal to or greater than the first temperature; and a control unit that, when the temperature of the battery at the time of starting the vehicle is less than the second temperature that is lower than the first temperature, performs control for executing the update process when the determination unit determines that the storage amount of the battery is equal to or greater than the first storage amount and the temperature of the battery is equal to or greater than the first temperature after the vehicle finishes traveling.

Abstract: At least one power line is connected to a battery mounted at a vehicle. Plural ECUs are each connected to the at least one power line. A processor switches one ECU at a time of the plural ECUs from a second state to a first state by sending state switching signals to the plural ECUs. A power line to which plural ECUs are connected is a target power line. On the basis of current values of the target power line measured by a current measurement section when these plural ECUs are switched to the first state one at a time, the processor determines whether or not each ECU is in an abnormal condition.

Abstract: At least one power line is connected to a battery mounted at a vehicle. Plural ECUs are each connected to the at least one power line. A processor switches one ECU at a time of the plural ECUs from a second state to a first state by sending state switching signals to the plural ECUs. A power line to which plural ECUs are connected is a target power line. On the basis of current values of the target power line measured by a current measurement section when these plural ECUs are switched to the first state one at a time, the processor determines whether or not each ECU is in an abnormal condition.

Abstract: A network system is mounted on a vehicle, and includes a plurality of sensors, a first bus used when the sensors transmit sensing data, a plurality of actuators, a second bus used when the actuators receive control data, a central electronic control unit that performs an operation based on the sensing data and generates the control data, a third bus used when the central electronic control unit receives the sensing data and transmits the control data, and a repeater. The repeater is configured to pass data flowing on the first bus to the third bus, pass data flowing on the third bus to the second bus, and block the flow of data from the third bus to the first bus and the flow of data from the second bus to the third bus.

Abstract: A network system is mounted on a vehicle, and includes a plurality of sensors, a first bus used when the sensors transmit sensing data, a plurality of actuators, a second bus used when the actuators receive control data, a central electronic control unit that performs an operation based on the sensing data and generates the control data, a third bus used when the central electronic control unit receives the sensing data and transmits the control data, and a repeater. The repeater is configured to pass data flowing on the first bus to the third bus, pass data flowing on the third bus to the second bus, and block the flow of data from the third bus to the first bus and the flow of data from the second bus to the third bus.

Abstract: A planar illumination device includes a light source unit, including a substantially planar emitting surface, configured to emit light to illuminate a substantially planar object, and a frame, formed in a frame shape enclosing the light source unit, disposed on an outer circumferential side of the light source unit, configured to hold the light source unit. The frame includes a reflecting part configured to reflect the light, and an absorbing part, formed integral with at least a part of an outer circumferential surface of the reflecting part, configured to absorb the light. The reflecting part and the absorbing part include joint interface therebetween that is inclined to a direction vertical to the emitting surface.

Abstract: A planar illumination device includes a light source unit, including a substantially planar emitting surface, configured to emit light to illuminate a substantially planar object, and a frame, formed in a frame shape enclosing the light source unit, disposed on an outer circumferential side of the light source unit, configured to hold the light source unit. The frame includes a reflecting part configured to reflect the light, and an absorbing part, formed integral with at least a part of an outer circumferential surface of the reflecting part, configured to absorb the light. The reflecting part and the absorbing part include joint interface therebetween that is inclined to a direction vertical to the emitting surface.

Abstract: A spread illuminating apparatus includes: a light guide plate including a plurality of protrusions disposed along a side surface thereof such that a plurality of interspaces are formed with each interspace being located between two adjacent protrusions; and a plurality of LEDs which include first row LEDs and second row LEDs disposed in two rows respectively at the interspaces and the protrusions. The distal portion of the protrusion has, at its top end surface, a width which is larger than the width of an opening area of the recess of a lamp house and also smaller than the overall width of the lamp house. The first and second row LEDs adjacent to each other are disposed such that respective lamp houses of two adjacent LEDs partly overlap with each other when viewed from the light emission direction.

Abstract: A keyboard apparatus. The apparatus has a housing including a plurality of key pads, including at least twenty six key pads spatially disposed within the housing. Each of the key pads is depressible upon touch by a user. An optically transparent circuit board is coupled to a backside of each of the key pads. The apparatus has a light guide characterized by a planar optically transparent material having a surface region, a width, a length, and a backside region, and a thickness provided between the surface region and the backside region. The apparatus has a plurality of patterns disposed on the surface region and optically coupled respectively to each of the twenty six key members. In a specific embodiment, the apparatus has a light emitting diode provided within a center region of the surface region to emit electromagnetic radiation.

Abstract: A spread illuminating apparatus includes: a light guide plate including a plurality of protrusions disposed along a side surface thereof such that a plurality of interspaces are formed with each interspace being located between two adjacent protrusions; and a plurality of LEDs which include first row LEDs and second row LEDs disposed in two rows respectively at the interspaces and the protrusions. The distal portion of the protrusion has, at its top end surface, a width which is larger than the width of an opening area of the recess of a lamp house and also smaller than the overall width of the lamp house. The first and second row LEDs adjacent to each other are disposed such that respective lamp houses of two adjacent LEDs partly overlap with each other when viewed from the light emission direction.

Abstract: A spread illuminating apparatus includes a light source, a light conductor plate having the light source at a side surface thereof, and a frame to house the light conductor plate, wherein the frame is basically composed of a metal core member and a resin body member which has an enclosed structure and which has recesses at outer surfaces of the enclosed structure.

Abstract: A planar lighting device in which workability of filling process of filler for heat radiation is improved and heat generated from a point-like light source is efficiently radiated so as to achieve higher brightness is provided. In a planar lighting device according to the present invention provided with a light guide plate and a point-like light source arranged on a side end face of the light guide plate, a radiator plate made of a bottom portion and a side wall is further provided, a circuit board on which the point-like light source is mounted is fixed along the side wall, and a recess portion holding a filler for heat radiation is formed at a position corresponding to the point-like light source in the side wall. By this arrangement, determination of an appropriate application amount of the filler for heat radiation and management and storage after application are facilitated and the workability of the filing process can be improved.

Abstract: A keyboard apparatus. The apparatus has a housing including a plurality of key pads, including at least twenty six key pads spatially disposed within the housing. Each of the key pads is depressible upon touch by a user. An optically transparent circuit board is coupled to a backside of each of the key pads. The apparatus has a light guide characterized by a planar optically transparent material having a surface region, a width, a length, and a backside region, and a thickness provided between the surface region and the backside region. The apparatus has a plurality of patterns disposed on the surface region and optically coupled respectively to each of the twenty six key members. In a specific embodiment, the apparatus has a light emitting diode provided within a center region of the surface region to emit electromagnetic radiation.

Abstract: A spread illuminating apparatus includes a light source, a light conductor plate having the light source at a side surface thereof, and a frame to house the light conductor plate, wherein the frame is basically composed of a metal core member and a resin body member which has an enclosed structure and which has recesses at outer surfaces of the enclosed structure.

Abstract: A spread illuminating apparatus includes: at least one light source; a light conductive plate which has the at least one light source disposed at one end surface thereof, and which allows light emitted from the at least one light source and introduced therein to exit out therefrom through both major surfaces thereof toward first and second liquid crystal display elements disposed respectively over the both major surfaces of the light conductive plate, wherein the second liquid crystal display element has a smaller display screen size than the first liquid crystal display element; and a reflecting means which is disposed at the other major surface of the light conductive plate so as to cover at least areas not covered by the second liquid crystal display element, and which reflects light toward the first liquid crystal display element.

Abstract: In a touch panel assembly, the thickness of a touch panel is successfully reduced by using a touch panel 10 provided with no reinforcement member. A housing frame 50 that supports the components of a front light unit 20 in an integral manner is provided with a touch panel positioning mechanism, and the touch panel 10 is fixed to the positioning mechanism, whereby the absence of a reinforcement member is duly compensated for, thus ensuring the strength of the touch panel 10. Deformation of the touch panel 10 that occurs when the touch panel 10 is pressed for operation can be attenuated by a transparent buffer member 5 disposed between the touch panel 10 and a light conductor plate 22. Therefore, the touch panel 10 deformed is prohibited from contacting and damaging the light conductor plate 22, thus preventing the light conductor plate 22 from deteriorating in its functional performance.

Abstract: In a spread illuminating apparatus comprising a spot-like light source, and a light conductive plate, the light conductive plate is shaped into a pentagon which has two sides thereof substantially parallel to each other. The pentagon includes, as a part thereof, a triangle having its base defined by an imaginary line connecting respective straightly opposing ends of the two parallel sides, and the spot-like light source is disposed at a side of the pentagon constituting one of two hypotenuses of the triangle.

Abstract: A housing frame includes a recess, a flat seat portion and a frame-shaped seat portion which are positioning units for a spot-like light source, a light conductive bar and a light conductive plate, respectively. The required assembly accuracy can be reliably obtained by fitting the light source, the light conductive bar and the light conductive plate to the predetermined positioning units of the housing frame. A recess and a flat seat portion have a thickness D2 smaller than the thickness D1 of a frame forming the positioning unit for the light conductive plate, and the housing frame forms a cavity, an opening of which is directed upward, and in order to obtain the required strength a reinforcing frame is provided. By reducing the thickness of the reinforcing frame, the light conductive plate can be disposed close to a display surface of any electronic product in incorporating the spread illuminating apparatus into any the electronic product.