Abstract: The present invention provides a substituted pyrrolidine compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof, has an orexin type 2 receptor agonist activity, and is useful as an agent for the prophylaxis or treatment of narcolepsy.

Abstract: The present invention provides a compound having a glucosylceramide lowering action (e.g., promoting glucosylceramide metabolism, inhibition of glucosylceramide synthesis, promoting glucosylceramide catabolism, etc.), which is expected to be useful as an agent for the prophylaxis or treatment of lysosome diseases (e.g., Gaucher's disease), neurodegenerative diseases (e.g., Parkinson's disease, Lewy body dementia, multiple-system atrophy) and the like. The present invention relates to a compound represented by the formula (I) wherein each symbol is as described in the specification, or a salt thereof.

Abstract: In order to provide a compact and low power consumption optical repeater capable of amplifying a plurality of wavelength ranges, the optical repeater is provided with: an excitation means which generates excitation light in a single wavelength range; a first light amplification means which is excited by the excitation light and the amplification band of which is a first wavelength range; and a second light amplification means which is excited by the excitation light and the amplification band of which is a second wavelength range different from the first wavelength range.

Abstract: Provided is a surface-treated steel sheet with a compound layer containing F and composed essentially or Zr at least on one surface thereof, wherein the Zr amount is 80 to 350 mg/m2 and the F amount is 0.5 to 10 mg/m2 within the layer, and an organic resin coated metal container manufactured using the surface-treated steel sheet. The surface-treated steel sheet of the present invention is manufactured through forming a layer having the Zr amount of 80 to 350 mg/m2 at least on one surface of a steel sheet by cathode electrolytic treatment in an aqueous solution containing a Zr ion and F ion, and subsequently adjusting the surface to control the F amount to 0.5 to 10 mg/m2 by one or more treatments selected from immersion and spraying with an ion-containing aqueous solution and cathode electrolytic treatment in the ion-containing aqueous solution.

Abstract: The object is to provide an optical repeater, a manufacturing method of an optical repeater, and a relay method of an optical signal that can achieve a redundant configuration for a failure of a light source outputting an excitation light with a simple configuration. Light sources output lights. The optical amplification units amplify optical signals using excitation lights. An optical distribution unit branches the lights output from the light sources into two branched lights and distributes the branched lights in such a manner that each of the optical amplification units receives the branched light branched from the lights from two different light sources as the excitation light.

Abstract: The present invention provides a substituted pyrrolidine compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof, has an orexin type 2 receptor agonist activity, and is useful as an agent for the prophylaxis or treatment of narcolepsy.

Abstract: The present invention provides a substituted pyrrolidine compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof, has an orexin type 2 receptor agonist activity, and is useful as an agent for the prophylaxis or treatment of narcolepsy.

Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof, has an orexin type 2 receptor agonist activity, and is useful as an agent for the prophylaxis or treatment of narcolepsy.

Abstract: The present invention provides a heterocyclic compound having an antagonistic action on an NMDA receptor containing the NR2B subunit, and expected to be useful as an agent for the prophylaxis or treatment of major depression, bipolar disorder, migraine, pain, behavioral and psychological symptoms of dementia and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof.

Abstract: The present invention aims to provide a heterocyclic compound having an AMPA receptor potentiator effect, which is expected to be useful as an agent for the prophylaxis or treatment of depression, Alzheimer's disease, schizophrenia, attention deficit hyperactivity disorder (ADHD) and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof.

Abstract: The present invention aims to provide a heterocyclic compound having an AMPA receptor potentiator effect, which is expected to be useful as an agent for the prophylaxis or treatment of depression, Alzheimer's disease, schizophrenia, attention deficit hyperactivity disorder (ADHD) and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof.

Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof, is useful as an agent for the prophylaxis or treatment of narcolepsy.

Abstract: In order to provide a compact and low power consumption optical repeater capable of amplifying a plurality of wavelength ranges, the optical repeater is provided with: an excitation means which generates excitation light in a single wavelength range; a first light amplification means which is excited by the excitation light and the amplification band of which is a first wavelength range; and a second light amplification means which is excited by the excitation light and the amplification band of which is a second wavelength range different from the first wavelength range.

Abstract: A repeater includes a pump light supplier configured to generate pump light; a first multiplexer configured to multiplex the pump light and a first wavelength division multiplexed optical signal; a second multiplexer configured to multiplex the pump light and a second wavelength division multiplexed optical signal; a first amplifier configured to amplify the first wavelength division multiplexed optical signal by use of the pump light; a second amplifier configured to amplify the second wavelength division multiplexed optical signal by use of the pump light; and a controller configured to control power of the pump light output to the first multiplexer and the second multiplexer, based on wavelength information about at least one of the first wavelength division multiplexed optical signal and the second wavelength division multiplexed optical signal.

Abstract: Provided is a signal loopback circuit which, in order to loop back a monitoring signal in a relay device for relaying optical signals of a plurality of wavelength bands, connects between a channel of first direction and a channel of second direction through which an optical signal of first wavelength band and an optical signal of second wavelength band are transmitted, wherein the signal loopback circuit is provided with a first coupler for branching the optical signal on the channel of first direction, a first filter for extracting at least one of a monitoring signal of first wavelength band and a monitoring signal of second wavelength band that are used in the channel of first direction from the optical signal branched by the first coupler, and a second coupler for causing the monitoring signal extracted by the first filter to be joined to the channel of the second direction.

Abstract: In order to provide a compact and low power consumption optical repeater capable of amplifying a plurality of wavelength ranges, the optical repeater is provided with: an excitation means which generates excitation light in a single wavelength range; a first light amplification means which is excited by the excitation light and the amplification band of which is a first wavelength range; and a second light amplification means which is excited by the excitation light and the amplification band of which is a second wavelength range different from the first wavelength range.

Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof, is useful as an agent for the prophylaxis or treatment of narcolepsy.

Abstract: The present invention provides a heterocyclic compound having an antagonistic action on an NMDA receptor containing the NR2B subunit, and expected to be useful as an agent for the prophylaxis or treatment of major depression, bipolar disorder, migraine, pain, behavioral and psychological symptoms of dementia and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof.

Abstract: Provided is a signal loopback circuit which, in order to loop back a monitoring signal in a relay device for relaying optical signals of a plurality of wavelength bands, connects between a channel of first direction and a channel of second direction through which an optical signal of first wavelength band and an optical signal of second wavelength band are transmitted, wherein the signal loopback circuit is provided with a first coupler for branching the optical signal on the channel of first direction, a first filter for extracting at least one of a monitoring signal of first wavelength band and a monitoring signal of second wavelength band that are used in the channel of first direction from the optical signal branched by the first coupler, and a second coupler for causing the monitoring signal extracted by the first filter to be joined to the channel of the second direction.

Abstract: In order to provide a compact and low power consumption optical repeater capable of amplifying a plurality of wavelength ranges, the optical repeater is provided with: an excitation means which generates excitation light in a single wavelength range; a first light amplification means which is excited by the excitation light and the amplification band of which is a first wavelength range; and a second light amplification means which is excited by the excitation light and the amplification band of which is a second wavelength range different from the first wavelength range.