Abstract: A series of fluorine-containing bisphosphonic acids in which an alkylamine side chain is added, a series of fluorine-containing bisphosphonic acids in which an amino group substituted by a heterocyclic group or a heterocyclic group containing a nitrogen atom is added, to the carbon atom of P—C(F)—P, and a series of fluorine-containing bisphosphonate derivatives in which the acid moiety thereof is esterified by an alkoxymethyl group such as POM group, n-butanoyloxymethyl (BuOM) group and the like, that is, the fluorine-containing bisphosphonic acid and fluorine-containing bisphosphonate derivative represented by the following formula (I): wherein each symbol is as defined in the DESCRIPTION, can efficiently induce proliferation of peripheral blood ?? T cells that express V?2V?2 T cell receptor having superior cytotoxicity against tumor cells and virus infected cells, immunize tumor cells and virus infected cells, and can induce cytotoxicity by ?? T cells.

Abstract: The present invention aims to provide a novel compound for measuring cellular cytotoxicity or cell proliferation capacity accurately with high reproducibility, conveniently and rapidly, and a measurement method of cellular cytotoxicity or cell proliferation capacity by using the compound. The present invention relates to a compound represented by the formula (I): wherein R1 is a substituent, R2 and R3 are each an optionally substituted hydrocarbon group, or an optionally substituted heterocyclic group, Y is a substituent, n is an integer of 0-3, Z is a single bond, —O—, —S—, —SO—, —SO2—, or —NR4— (R4 is a hydrogen atom or a substituent), and A is an optionally substituted C1-6 alkylene group) or a salt thereof.

Abstract: Provided is an electronic device that can be appropriately used as a type of electronic device that vibrates a panel attached to a housing. The electronic device includes a piezoelectric element, a panel, to which the piezoelectric element is attached, that vibrates due to the piezoelectric element to generate a vibration sound transmitted by vibrating a part of a human body, a housing supporting the panel with a first face, a microphone contained within the housing and disposed on a second face, and a buffer that damps vibration transmitted from the panel to the microphone through the first face and/or the second face, thereby reducing noise picked up by the microphone.

Abstract: A series of fluorine-containing bisphosphonic acids in which an alkylamine side chain is added, a series of fluorine-containing bisphosphonic acids in which an amino group substituted by a heterocyclic group or a heterocyclic group containing a nitrogen atom is added, to the carbon atom of P—C(F)—P, and a series of fluorine-containing bisphosphonate derivatives in which the acid moiety thereof is esterified by an alkoxymethyl group such as POM group, n-butanoyloxymethyl (BuOM) group and the like, that is, the fluorine-containing bisphosphonic acid and fluorine-containing bisphosphonate derivative represented by the following formula (I): wherein each symbol is as defined in the DESCRIPTION, can efficiently induce proliferation of peripheral blood ?? T cells that express V?2V?2 T cell receptor having superior cytotoxicity against tumor cells and virus infected cells, immunize tumor cells and virus infected cells, and can induce cytotoxicity by ?? T cells.

Abstract: An electronic device includes a vibration unit configured to generate a vibration sound transmitted by vibrating a contacting or pressing body part; and piezoelectric elements stacked on and attached to the vibration unit and vibrating the vibration unit in accordance with an input signal. The piezoelectric elements each have a different capacitance. Voltage of the input signal to the piezoelectric elements is varied in accordance with frequency band, thereby suppressing power consumption.

Abstract: Provided are a polycyclic pyrazolinone derivative indicated by general formula (1) (in the formula, R1, X1, X2, X3, and Y indicate the definitions provided in the Specification) and a herbicide comprising same as effective component thereof.

Abstract: Provided is an electronic device including: a housing; a vibration body disposed in the housing; and a microphone disposed in the housing. By vibrating the vibration body, the electronic device transmits air conduction sound and vibration sound that is generated by the vibration. During the generation of the sounds, howling reduction processing is performed, so that usability of the electronic device is improved.

Abstract: The present invention aims to provide a novel compound for measuring cellular cytotoxicity or cell proliferation capacity accurately with high reproducibility, conveniently and rapidly, and a measurement method of cellular cytotoxicity or cell proliferation capacity by using the compound. The present invention relates to a compound represented by the formula (I): wherein R1 is a substituent, R2 and R3 are each an optionally substituted hydrocarbon group, or an optionally substituted heterocyclic group, Y is a substituent, n is an integer of 0-3, Z is a single bond, —O—, —S—, —SO—, —SO2—, or —NR4— (R4 is a hydrogen atom or a substituent), and A is an optionally substituted C1-6 alkylene group) or a salt thereof.

Abstract: Provided is an electronic device including a housing and an acoustic device configured to generate vibration sound that is transmitted through vibration of a part of a human body. The acoustic device includes a panel configured to be joined to the housing; a piezoelectric element configured to be joined to the panel for vibrating the panel; and a vibration adjusting unit configured to be joined to the panel and vibrated together with the panel by the piezoelectric element. With the above configuration, a frequency characteristic is improved.

Abstract: According to an aspect, a communication system includes a mobile communication device and a communication device. The mobile communication device includes: a position information acquiring unit configured to acquire its own position information; and a communication unit configured to transmit the position information and an emergency signal. The communication device is configured to display, when detecting that the emergency signal and the position information of the mobile communication device are transmitted from the mobile communication device, the position information of the mobile communication device and its own position information on a display unit.

Abstract: The content of sound leakage from a vibrating plate that vibrates due to a piezoelectric element is made difficult to recognize. An electronic device (1) according to the present invention includes a piezoelectric element (30) and a vibrating plate (10) that vibrates due to the piezoelectric element (30), the electronic device (1) causing the vibrating plate (10) to generate air-conducted sound and vibration sound that is transmitted by vibrating a part of a human body. The electronic device (1) also includes an air-conducted sound reducing unit that makes a portion or all of the air-conducted sound difficult to hear.

Abstract: An echo caused by sound leakage from a housing that vibrates due to a vibrating body is reduced. An electronic device (1) according to the present invention includes a piezoelectric element (30), a vibrating plate (10) that vibrates due to the piezoelectric element (30), microphones (42, 43), and an equalizer (44), the electronic device (1) causing the vibrating plate (10) to generate air-conducted sound and vibration sound that is transmitted by vibrating a part of a human body. The equalizer (44) makes a low-range emphasis setting, to emphasize a low frequency range more than a high frequency range of the air-conducted sound, when the volume of the air-conducted sound collected by the microphones (42, 43) exceeds a predetermined threshold.

Abstract: An electronic device (1) is provided with a piezoelectric element (30), a panel (10) holding the piezoelectric element (30), and a housing (60) holding the panel (10) and transmitting vibration through the panel (10). The electronic device (1) causes the panel (10) to generate vibration sound that is transmitted by vibrating a part of a human body. The electronic device (1) includes a stiffness varying portion (62, 63) in which the stiffness of the housing (60) varies.

Abstract: The electronic device including a piezoelectric element, a vibration plate having the piezoelectric element fixed thereto for generating air conduction sound by vibrating the piezoelectric element and sound to be transmitted by vibrating a part of a human body, a housing having the vibration plate fixed thereto, and an operation key provided to the housing, makes vibration of the vibration plate not likely to be transmitted to the operation key.

Abstract: Provided is an electronic device including a housing and an acoustic device configured to generate vibration sound that is transmitted through vibration of a part of a human body. The acoustic device includes a panel configured to be joined to the housing; a piezoelectric element configured to be joined to the panel for vibrating the panel; and a vibration adjusting unit configured to be joined to the panel and vibrated together with the panel by the piezoelectric element. With the above configuration, a frequency characteristic is improved.

Abstract: Provided are a polycyclic pyrazolinone derivative indicated by general formula (1) (in the formula, R1, X1, X2, X3, and Y indicate the definitions provided in the Specification) and a herbicide comprising same as effective component thereof.

Abstract: An electronic device includes a vibration unit configured to generate a vibration sound transmitted by vibrating a contacting or pressing body part; and piezoelectric elements stacked on and attached to the vibration unit and vibrating the vibration unit in accordance with an input signal. The piezoelectric elements each have a different capacitance. Voltage of the input signal to the piezoelectric elements is varied in accordance with frequency band, thereby suppressing power consumption.

Abstract: In order to be appropriately usable as an electric device for vibrating a panel attached to a housing, an electronic device including a piezoelectric element; a housing having a first principle plane having the piezoelectric element fixed thereto and a second principle plane opposite to the first principle plane; and a lid member having a joint portion for removably joining to the second principle plane; causes the housing to generate sound transmitted by vibrating a part of a human body, such that the piezoelectric element is provided on a first side in a first direction parallel to the first principle plane, and a joint position of the joint portion is provided on a second side opposite to the first side in the first direction.

Abstract: Provided is an electronic device including a housing and an acoustic device configured to generate vibration sound that is transmitted through vibration of a part of a human body. The acoustic device includes a panel configured to be joined to the housing; a piezoelectric element configured to be joined to the panel for vibrating the panel; and a vibration adjusting unit configured to be joined to the panel and vibrated together with the panel by the piezoelectric element. With the above configuration, a frequency characteristic is improved.

Abstract: Provided is an electronic device that is capable of reducing sound leakage from a vibration plate vibrated by a piezoelectric element. An electronic device 1 of the present invention includes: a piezoelectric element 30; and a vibration plate 10 configured to be vibrated by the piezoelectric element 30. Vibration sound is transmitted by the vibration plate vibrating a part of a human body. The piezoelectric element 30 is vibrated using a processed sound signal in which at least a part of frequency components of a sound reproduction signal that are higher than a predetermined threshold value is cut or attenuated.