Abstract: The present invention provides an agent that suppresses a decrease in arterial oxygen saturation or increases decreased arterial oxygen saturation, and that can be ingested by a relatively simple method and has excellent immediate effectivity and persistence. The agent of the invention comprises orotic acid or a salt thereof as an active ingredient, which is absorbed into the body via oral mucosa. When the agent is absorbed in the body via oral mucosa it suppresses a decrease in arterial oxygen saturation or increases decreased arterial oxygen saturation. The agent is effective for improvement or prevention of a symptom or disease related to a decrease in arterial oxygen saturation, such as exercise, alcohol drinking, a decrease in oxygen concentration in air, reduced cardiopulmonary function, and respiratory arrest, and a symptom or disease caused by hypoxia, in particular, for prevention of an increase in uric acid level.

Abstract: The present invention provides an agent that suppresses a decrease in arterial oxygen saturation or increases decreased arterial oxygen saturation, and that can be ingested by a relatively simple method and has excellent immediate effectivity and persistence. The agent of the invention comprises orotic acid or a salt thereof as an active ingredient, which is absorbed into the body via oral mucosa. When the agent is absorbed in the body via oral mucosa it suppresses a decrease in arterial oxygen saturation or increases decreased arterial oxygen saturation. The agent is effective for improvement or prevention of a symptom or disease related to a decrease in arterial oxygen saturation, such as exercise, alcohol drinking, a decrease in oxygen concentration in air, reduced cardiopulmonary function, and respiratory arrest, and a symptom or disease caused by hypoxia, in particular, for prevention of an increase in uric acid level.

Abstract: A soundproof type engine working machine comprising a soundproof casing containing therein an engine and a working machine such as for example a dynamo driven by the engine and situated one behind another in the rotary axis direction. In this engine working machine, a main air inlet port into the soundproof casing is formed in a bottom portion of the soundproof casing and at the side where the working machine is situated, a fan for cooling the working machine is mounted to the working machine and a fan for cooling the engine is mounted to the engine, respectively, and a fan cover for covering the engine cooling fan is communicated with a duct covering a cylinder portion of the engine and an exhaust muffler and opened up outside of the soundproof casing at an end portion thereof, a cooling air by the working machine cooling fan being introduced to the duct after the air cooled the working machine. An oil pan cooling air passage is disposed along an oil pan portion of the engine.