Abstract: An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof. The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below: R1: e.g., a C1-C6 alkyl group; R2: a C1-C6 alkyl group; A: e.g., an oxygen atom; and R3: e.g., a C1-C6 alkyl group.

Abstract: A portable electrocardiograph includes: a recording section configured to record data corresponding to electrocardiogram of a subject; a detecting section configured to detect approach of a portable device having a function to perform short-range wireless communication; and a control section configured to start recording of the data in the recording section in a case where it is satisfied a start condition including a fact that the approach of the device is detected by the detecting section.

Abstract: A vital sign information recording system includes a data collector configured to collect behavior-associated information of a subject and vital sign information of the subject, and a display configured to display a presumed behavior of the subject and the vital sign information of the subject. At least one of the data collector and the display has a controller configured to determine the presumed behavior of the subject based on the behavior-associated information, and to display the presumed behavior of the subject and the vital sign information of the subject in a mutually associated manner on the display.

Abstract: A portable electrocardiograph includes: a recording section configured to record data corresponding to electrocardiogram of a subject; a detecting section configured to detect approach of a portable device having a function to perform short-range wireless communication; and a control section configured to start recording of the data in the recording section in a case where it is satisfied a start condition including a fact that the approach of the device is detected by the detecting section.

Abstract: As antibody variants and isoforms having reduced FVIII mimetic activity than Emicizumab, the antibody variants having some specific amino acid residues in the variable region cleaved out and missing (Q-CDR-Clipped Variants) and the antibody isoforms having inter-heavy chain disulfide bonds less susceptible to reduction under mild reducing conditions (Protected Disulfide Isoforms) are provided.

Abstract: A vital sign information recording system includes a data collector configured to collect behavior-associated information of a subject and vital sign information of the subject, and a display configured to display a presumed behavior of the subject and the vital sign information of the subject. At least one of the data collector and the display has a controller configured to determine the presumed behavior of the subject based on the behavior-associated information, and to display the presumed behavior of the subject and the vital sign information of the subject in a mutually associated manner on the display.

Abstract: Provided is an ion sensor including a supporting substrate, a plurality of cells, a silicon substrate, a plurality of transistors, and an analog-digital conversion circuit. The plurality of cells, the plurality of transistors, and the analog-digital conversion circuit are provided above the supporting substrate. Each of the plurality of transistors has a corresponding gate provided on a first surface of the silicon substrate. The analog-digital conversion circuit is provided on the silicon substrate. The ion-sensing surface is provided on a second surface of the silicon substrate. The second surface is opposite to the first surface.

Abstract: An ion sensor is configured such that part of a P well on which part a sensing section is provided is different, in dopant concentration, from the other part of the P well so that electric charges are injected merely to the sensing section in a state where a voltage is applied to an N-type substrate.

Abstract: Provided is an ion sensor including a supporting substrate, a plurality of cells, a silicon substrate, a plurality of transistors, and an analog-digital conversion circuit. The plurality of cells, the plurality of transistors, and the analog-digital conversion circuit are provided above the supporting substrate. Each of the plurality of transistors has a corresponding gate provided on a first surface of the silicon substrate. The analog-digital conversion circuit is provided on the silicon substrate. The ion-sensing surface is provided on a second surface of the silicon substrate. The second surface is opposite to the first surface.

Abstract: A biological information displaying apparatus includes an analyzing unit and a display unit. The analyzing unit analyzes measured continuous biological information waveforms to detect abnormal biological information waveforms.

Abstract: An ion sensor is configured such that part of a P well on which part a sensing section is provided is different, in dopant concentration, from the other part of the P well so that electric charges are injected merely to the sensing section in a state where a voltage is applied to an N-type substrate.

Abstract: A relay apparatus (10) is provided with: an image output unit (11); switches (SWa, SWb); a control unit (16) for controlling switches; and an obtaining unit (16) for obtaining a first CEC address associated with the relay apparatus if the relay apparatus is connected to an output apparatus (30). The control unit controls switches to select a signal channel connecting a first signal transmitting device (14) and a storage apparatus (20) if the first CEC address and a reproduction command are received. After connecting the relay apparatus and a unit (40), the control unit controls switches to select the signal channel connecting the first signal transmitting device and a second signal transmitting device (15) if the unit is in a video output state, and controls switches to select the signal channel connecting the first signal transmitting device and the image output unit if the unit is in a standby state.

Abstract: A relay apparatus (10) is provided with: an image output unit (11); switches (SWa, SWb); a control unit (16) for controlling switches; and an obtaining unit (16) for obtaining a first CEC address associated with the relay apparatus if the relay apparatus is connected to an output apparatus (30). The control unit controls switches to select a signal channel connecting a first signal transmitting device (14) and a storage apparatus (20) if the first CEC address and a reproduction command are received. After connecting the relay apparatus and a unit (40), the control unit controls switches to select the signal channel connecting the first signal transmitting device and a second signal transmitting device (15) if the unit is in a video output state, and controls switches to select the signal channel connecting the first signal transmitting device and the image output unit if the unit is in a standby state.

Abstract: A biological information displaying apparatus includes an analyzing unit and a display unit. The analyzing unit analyzes measured continuous biological information waveforms to detect abnormal biological information waveforms.

Abstract: According to the present invention, ethanol production is carried out with the use of cellulose or cellobiose as a starting material at low cost. The method of the present invention comprises the steps of culturing a microorganism that is classified as a species selected from the group consisting of Ogataea dorogensis, Ogataea pini, Ogataea glucozyma, Ogataea neopini, and Ogataea corticis in a medium containing cellobiose; and collecting ethanol from the medium.

Abstract: According to the present invention, ethanol production is carried out with the use of cellulose or cellobiose as a starting material at low cost. The method of the present invention comprises the steps of culturing a microorganism that is classified as a species selected from the group consisting of Ogataea dorogensis, Ogataea pini, Ogataea glucozyma, Ogataea neopini, and Ogataea corticis in a medium containing cellobiose; and collecting ethanol from the medium.

Abstract: This invention provides a polynucleotide that encodes a protein having lactate dehydrogenase activity and such protein that can be used for producing D-lactic acid. This polynucleotide has the nucleotide sequence as shown in SEQ ID NO: 1 (a), and it hybridizes under stringent conditions with a probe comprising all or part of the nucleotide sequence as shown in SEQ ID NO: 1 or a complementary strand thereof and encodes a protein having D-lactate dehydrogenase activity (b).

Abstract: The invention provides a promoter that can be used in the presence of an organic acid. The promoter includes DNA with promoter activity of high osmolarity response 7 gene (HOR7 gene), glycelaldehyde 3 phosphate dehydrogenase 2 gene (TDH2 gene), heat shock protein 30 gene (HSP30), hexose transport protein 7 gene (HXT7 gene), thioredoxin peroxidase 1 gene (AHP1 gene), or membrane protein 1 associated gene gene) of yeasts.

Abstract: A content reproducing device (10) capable of changing over from a title list where purchased contents and unpurchased contents are mixedly listed directly to the content purchase procedure and reproducing an unpurchased content as a purchased content. The content reproducing device (10) comprises a storage medium (13) storing purchased viewable contents and unpurchased nonviewable contents, a content list generating portion (11) for making a list of the contents stored in the storage medium (13), and a controlling portion (14) for allowing a displaying apparatus (30) to display the content list made. The content list shows the contents irrespective of whether each of them has been purchased or not. Through the content list, the user can be directly authenticated by a content reproduction authentication server (50) to perform the purchase procedure. After the purchase procedure is ended, the unpurchased content is changed to a purchased content, and the content can be reproduced as it is.

Abstract: This invention provides a polynucleotide that encodes a protein having lactate dehydrogenase activity and such protein that can be used for producing D-lactic acid. This polynucleotide has the nucleotide sequence as shown in SEQ ID NO: 1 (a), and it hybridizes under stringent conditions with a probe comprising all or part of the nucleotide sequence as shown in SEQ ID NO: 1 or a complementary strand thereof and encodes a protein having D-lactate dehydrogenase activity (b).