Abstract: The present invention pertains to an enzymatic measurement method using an antibody-enzyme complex or a nucleic acid probe measurement method using an enzyme-labeled nucleic acid probe, in both of which the quantification of a product of a reaction by an enzyme in the antibody-enzyme complex or the enzyme-labeled nucleic acid probe is performed by generating thio-NAD(P)H by an enzymatic cycling reaction using NAD(P)H, thio-NAD(P), and a dehydrogenase (DH), and measuring the amount of the generated thio-NAD(P)H or measuring a change in color caused by the generated thio-NAD(P)H. An enzymatic reaction system in which NAD(P) generated from NAD(P)H by the enzymatic cycling reaction is selectively reduced, is caused to coexist with the enzymatic cycling reaction. The present invention also pertains to a kit for enzyme immunoassay, and a kit for nucleic acid probe measurement.

Abstract: Provided is a ultra-high-sensitivity assay in which the assay can be made on a commonly used assay apparatus such as an absorptiometer and a plate reader or with naked eyes. The high-sensitivity assay in which the assay can be made on a commonly used assay apparatus or with naked eyes can be provided by combining an enzyme cycling method using thio-NAD(P) as a coenzyme, a labeling enzyme and a substrate for the labeling enzyme optimally, and by amplifying thio-NAD(P)H, which is a signaling substance, exponentially and then quantifying the thio-NAD(P)H colorimetrically.

Abstract: There is provided an antitumor agent for acute myeloid leukemia, which exhibits a practical curing effect on acute myeloid leukemia. According to the present invention, there is provided the antitumor agent for acute myeloid leukemia, whose dose per administration is within a predetermined range and which contains a compound represented by General Formula [1] specified in the present specification, such as (S,E)-N-(1-((5-(2-((4-cyanophenyl)amino)-4-(propylamino)pyrimidin-5-yl)-4-pentyn-1-yl)amino)-1-oxopropan-2-yl)-4-(dimethylamino)-N-methyl-2-butenamide or a salt thereof.

Abstract: The present invention pertains to an enzymatic measurement method using an antibody-enzyme complex or a nucleic acid probe measurement method using an enzyme-labeled nucleic acid probe, in both of which the quantification of a product of a reaction by an enzyme in the antibody-enzyme complex or the enzyme-labeled nucleic acid probe is performed by generating thio-NAD(P)H by an enzymatic cycling reaction using NAD(P)H, thio-NAD(P), and a dehydrogenase (DH), and measuring the amount of the generated thio-NAD(P)H or measuring a change in color caused by the generated thio-NAD(P)H. An enzymatic reaction system in which NAD(P) generated from NAD(P)H by the enzymatic cycling reaction is selectively reduced, is caused to coexist with the enzymatic cycling reaction. The present invention also pertains to a kit for enzyme immunoassay, and a kit for nucleic acid probe measurement.

Abstract: Provided is a ultra-high-sensitivity assay in which the assay can be made on a commonly used assay apparatus such as an absorptiometer and a plate reader or with naked eyes. The high-sensitivity assay in which the assay can be made on a commonly used assay apparatus or with naked eyes can be provided by combining an enzyme cycling method using thio-NAD(P) as a coenzyme, a labeling enzyme and a substrate for the labeling enzyme optimally, and by amplifying thio-NAD(P)H, which is a signaling substance, exponentially and then quantifying the thio-NAD(P)H colorimetrically.

Abstract: A coil-embedded dust core of the present invention is provided with a molded coil component including a coil main body having a structure in which a flat type conductor wire is wound edgewise, one end side terminal portion disposed by being lead in the thickness direction of the coil main body, the other end side terminal portion, one end side leading electrode portion disposed by extending the one end side terminal portion, and the other end side leading electrode portion disposed by extending the other end side terminal portion; and a dust core composed of a soft magnetic alloy powder disposed covering the coil main body, the one end side terminal portion, and the other end side terminal portion of the molded coil component.

Abstract: A coil-embedded dust core of the present invention is provided with a molded coil component including a coil main body having a structure in which a flat type conductor wire is wound edgewise, one end side terminal portion disposed by being lead in the thickness direction of the coil main body, the other end side terminal portion, one end side leading electrode portion disposed by extending the one end side terminal portion, and the other end side leading electrode portion disposed by extending the other end side terminal portion; and a dust core composed of a soft magnetic alloy powder disposed covering the coil main body, the one end side terminal portion, and the other end side terminal portion of the molded coil component.

Abstract: A pectinase for degradation a pectin or pectic acid is disclosed wherein(1) the novel pectinase is an endopolygalacturonase produced from a, Saccharomyces bayanus,(2) the optimal pH is 4.0,(3) the stable pH range is 4.0 to 8.0,(4) the optimal temperature is 45.degree. C.,(5) the enzymatic activity is stable up to 45.degree. C., and(6) the molecular weight is 38,000. A low-molecular pectin having a low viscosity and a high solubility and maintaining the physiological activity as the dietary fiber, and food and drink each of which contains 0.01 to 50 wt % of the low molecular pectin are also disclosed.