Abstract: The present invention relates to a method for analyzing a metalloprotein in a biological sample capable of continuously maintaining conditions of LC-ICPMS constant to measure a metalloprotein with high data reliability. The method for analyzing a metalloprotein which is a complex in a biological sample, the metalloprotein being a complex in which a biomolecule and a metal element bind to each other, includes: treating a biological sample which has been subjected to a pretreatment by liquid chromatography to separate the metalloprotein, and analyzing the separated metalloprotein by inductively coupled plasma mass spectrometry, wherein an ammonium acetate solution is used as a mobile phase.

Abstract: A subject matter of the present disclosure is to facilitate the permeation of a water-soluble agent into the skin. An application type body-correcting-film forming agent of the present disclosure comprises a first agent comprising a cross-linking reactive ingredient that constitutes a body-correcting film; and a second agent comprising a catalyst for cross-linking the cross-linking reactive ingredient, wherein at least one of the first agent and the second agent comprises a water-soluble agent.

Abstract: To provide a second agent for a coating-type body corrective film formation agent that can shorten the cross-linking reaction time in film formation and improve the durability of the film to be obtained. An oil-in-water composition of the present disclosure comprises a dispersion medium containing water, and oil droplets dispersed in this dispersion medium, wherein the oil droplets comprise an oil, and a catalyst that serves as a cross-linking ingredient, wherein the oil-in-water composition is used as a second agent for a coating-type body corrective film formation agent comprising a first agent comprising a cross-linking reactive ingredient that constitutes a body corrective film; and a second agent comprising a cross-linking ingredient for cross-linking the cross-linking reactive ingredient.

Abstract: A water-in-oil type emulsified cosmetic has an unprecedented property wherein, by coming into contact with perspiration or water, the color development and the color uniformity are improved over the conditions immediately after application. The water-in-oil type emulsified cosmetic includes: (A) an organically modified clay mineral; (B) an oil phase thickener other than the (A) organically modified clay mineral; (C) a non-volatile liquid oil other than a silicone oil; (D) a silicone-based surfactant having an HLB of less than 8; and (E) a colorant; wherein a weight ratio defined by [(A)+(B)]/(C) is at least 0.04 and less than 0.68.

Abstract: An oil-in-water emulsified sunblock cosmetic has excellent feeling when used and maintains a high ultraviolet-ray protective effect even upon contact with water or sweat. The oil-in-water emulsified sunblock cosmetic contains an (A) ultraviolet-ray protective agent and a (B) fatty acid forming a solid at room temperature, the cosmetic is characterized in that 51% or less of the fatty acid is neutralized, and the formulation ratio ((A)/(B) of the (A) ultraviolet-ray protective agent to the (B) fatty acid is in the range of at least 0.1 and less than 10.0. The cosmetic exhibits the unprecedented and surprising property of contact with water causing an improvement to the ultraviolet-ray protective ability. It is preferable for the cosmetic to contain an (C) oily component having IOB of 0.5 or higher.

Abstract: The object is providing a water-in-oil emulsion sunscreen cosmetic having a property not present in the prior art, in which UV protection ability improve upon contact with water, sweat and the like in comparison with that directly after application, and also having pleasant texture and easy to wash off. The present invention provides a water-in-oil emulsion sunscreen cosmetic comprising (A) 6 to 40 mass % of a UV protective agent; (B) an organic-modified clay mineral; (C) an oil-phase-thickening agent, other than (B) and (D) a silicone-based surfactant having an HLB of less than 8, wherein the ratio, [total quantity of component (B) and component (C)]/[total quantity of (E) non-volatile liquid oils except silicone oils], is 0.04 or more and less than 0.68.

Abstract: The present invention relates to an oil-based cosmetic having the innovative, unprecedented property in which the ultraviolet protection effects increase due to heat. The oil-based cosmetic of the present invention contains (A) an ultraviolet protectant; and (B) at least one compound that is water-soluble and that has an IOB of 5.0 or lower, selected from among (i) alkylene oxide derivatives and (ii) polyhydric alcohols; wherein the (B) (i) alkylene oxide derivatives are polyoxyalkylene/polyoxyethylene copolymer dialkyl ethers represented by the following formula (I): R1O-[(AO)m(EO)n]—R2??(I) wherein R1 and R2, each independently, denote a hydrogen atom or a hydrocarbon group having one to four carbon atoms, AO denotes an oxyalkylene group having three or four carbon atoms, EO denotes an oxyethylene group, 1?m?70, 1?n?70 and m+n?40; and the oil-based cosmetic has a water content of 5% by mass or less.

Abstract: A support structure includes a shroud having a substantially circular shape from a proximal end covering an outer periphery of a first surface of a heat exchanger to a distal end. A support frame supports the heat exchanger and the shroud to expose the distal end and a second surface of the heat exchanger. The vehicle body frame has an opening. A cooling fan includes a fan rotating shaft and blades to generate cooling air. When the heat exchanger is positioned at the first position facing the cooling fan, the distal end of the shroud covers a circumference of the cooling fan in a radial direction so that cooling air passes through the first and second surfaces. When the support frame is located at a second position where the heat exchanger exposes the opening to an outside of the vehicle frame, the fan rotating shaft and the blades are uncovered.

Abstract: There is provided a composition for forming an artificial skin that can shorten the cross-linking time while maintaining excellent application performance and coating performance. A composition for forming an artificial skin of the present disclosure comprises a first agent and a second agent, wherein the first agent comprises: (a) a polymer A composed of one or more organopolysiloxanes containing at least two carbon-carbon double bonds or at least one carbon-carbon triple bond in the molecule; (b) a polymer B composed of one or more organopolysiloxanes containing at least two Si—H units in the molecule; and (c) a silicone having a viscosity of 1.5 mPa·s or less at 25° C., and wherein the second agent comprises a catalyst that promotes cross-linking of the polymer A and the polymer B.

Abstract: The purpose of the present invention is to newly provide a method with which it is possible to appropriately evaluate the protective effect of an external preparation for skin such as a sunscreen cosmetic, particularly to evaluate how a UV-ray protective effect is affected by heat. This evaluation method is characterized by including (1) a step for forming a coating film of an external preparation for skin on a substrate, (2) a step for heat-treating the coating film of the external preparation for skin, and (3) a step for measuring the UV-ray protective effect of the heat-treated coating film of the external preparation for skin. The heat treatment is preferably carried out for at least one minute at a temperature of 30-70° C.

Abstract: The invention provides a cosmetic having strong resistance to contact with water, clothing, fingers, and abrasion with little decline (post-contact) in the cosmetic effects such as UV blocking protection as well as excellent feel on use. The cosmetic contains: (A) plate-shaped powder, (B) 6-40% by mass UV absorber, and (C) cationic surfactant.

Abstract: A water-in-oil emulsified cosmetic preparation that, even without substantially comprising a UV scattering agent: exhibits a higher UV protection effect than immediately after application, as a result of coming in contact with moisture, has excellent appearance, usability, and washability. The water-in-oil emulsified cosmetic preparation includes 6%-40% by mass of a UV absorber (A), an oil phase thickener (B), and at least one hydrophobic powder (C) selected from (i)-(iii), namely (i) hydrophobized talc, (ii) silicone powder having an average particle diameter of at least 30 ?m, and (iii) crosslinked polymethyl methacrylate powder having a crosslinking density of at least 40%; and not including a UV scattering agent or containing no more than 6% by mass of same.

Abstract: The present invention relates to a cosmetic in which the ultraviolet protection effects are increased by heat, and a method for manufacture thereof. The manufacturing method of the present invention includes (1) a step of preparing a sample composition containing (A) an ultraviolet protectant and (B) one or more humectants that have an IOB of 5.

Abstract: Provided is an emulsion cosmetic having the innovative, unprecedented property in which the ultraviolet protection effects do not decrease, and conversely increase, due to heat applied in a usage environment. The present invention pertains to an emulsion cosmetic comprising (A) an ultraviolet protectant, (B) a polyhydric alcohol having an IOB value of 5.0 or lower, and (C) an ester oil having an IOB value of 0.3 or higher.

Abstract: The present invention relates to an oil-based cosmetic having the innovative, unprecedented property in which the ultraviolet protection effects increase due to heat. The oil-based cosmetic of the present invention contains (A) an ultraviolet protectant; and (B) at least one compound that is water-soluble and that has an IOB of 5.0 or lower, selected from among (i) alkylene oxide derivatives and (ii) polyhydric alcohols; wherein the (B) (i) alkylene oxide derivatives are polyoxyalkylene/polyoxyethylene copolymer dialkyl ethers represented by the following formula (I): R1O-[(AO)m(EO)n]—R2 ??(I) wherein R1 and R2, each independently, denote a hydrogen atom or a hydrocarbon group having one to four carbon atoms, AO denotes an oxyalkylene group having three or four carbon atoms, EO denotes an oxyethylene group, 1?m?70, 1?n?70 and m+n?40; and the oil-based cosmetic has a water content of 5% by mass or less.

Abstract: The present invention relates to a method for analyzing a metalloprotein in a biological sample capable of continuously maintaining conditions of LC-ICPMS constant to measure a metalloprotein with high data reliability. The method for analyzing a metalloprotein which is a complex in a biological sample, the metalloprotein being a complex in which a biomolecule and a metal element bind to each other, includes: treating a biological sample which has been subjected to a pretreatment by liquid chromatography to separate the metalloprotein, and analyzing the separated metalloprotein by inductively coupled plasma mass spectrometry, wherein an ammonium acetate solution is used as a mobile phase.

Abstract: A water-in-oil emulsified cosmetic preparation that, even without substantially comprising a UV scattering agent, exhibits a high UV protection effect. This water-in-oil emulsified cosmetic preparation includes: 6%-40% by mass of a UV absorber (A); at least 15% by mass of a non-volatile polar oil component (B) containing an ester bond (and not including the UV absorber (A)); and 0.5%-15% by mass of an oil phase thickener (C). It is particularly preferable that the present invention also includes a powder (D) having an average particle diameter of no more than 15 ?m.

Abstract: The purpose of the present invention is to newly provide a method with which it is possible to appropriately evaluate the protective effect of an external preparation for skin such as a sunscreen cosmetic, particularly to evaluate how a UV-ray protective effect is affected by heat. This evaluation method is characterized by including (1) a step for forming a coating film of an external preparation for skin on a substrate, (2) a step for heat-treating the coating film of the external preparation for skin, and (3) a step for measuring the UV-ray protective effect of the heat-treated coating film of the external preparation for skin. The heat treatment is preferably carried out for at least one minute at a temperature of 30-70° C.

Abstract: The invention provides a cosmetic having strong resistance to contact with water, clothing, fingers, and abrasion with little decline (post-contact) in the cosmetic effects such as UV blocking protection as well as excellent feel on use. The cosmetic contains: (A) plate-shaped powder, (B) 6-40% by mass UV absorber, and (C) cationic surfactant.

Abstract: A water-in-oil emulsified cosmetic preparation that, even without substantially comprising a UV scattering agent: exhibits a higher UV protection effect than immediately after application, as a result of coming in contact with moisture, has excellent appearance, usability, and washability. The water-in-oil emulsified cosmetic preparation includes 6%-40% by mass of a UV absorber (A), an oil phase thickener (B), and at least one hydrophobic powder (C) selected from (i)-(iii), namely (i) hydrophobized talc, (ii) silicone powder having an average particle diameter of at least 30 ?m, and (iii) crosslinked polymethyl methacrylate powder having a crosslinking density of at least 40%; and not including a UV scattering agent or containing no more than 6% by mass of same.