Patent number: 10000488
Abstract: The problem of the present invention is to provide a compound having a superior ROR?t inhibitory action, and useful as a prophylactic or therapeutic agent for psoriasis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, rheumatoid arthritis, multiple sclerosis, uveitis, asthma, ankylopoietic spondylarthritis, systemic lupus erythematosus, chronic obstructive pulmonary disease or the like. The present invention relates to a compound represented by the formula (I): [wherein each symbol is as described in the DESCRIPTION] or a salt thereof, which has an ROR?t inhibitory action, and useful as a prophylactic or therapeutic agent for psoriasis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, rheumatoid arthritis, multiple sclerosis, uveitis, asthma, ankylopoietic spondylarthritis, systemic lupus erythematosus, chronic obstructive pulmonary disease or the like.
Type:
Grant
Filed:
September 10, 2015
Date of Patent:
June 19, 2018
Assignee:
Takeda Pharmaceutical Company Limited
Inventors:
Satoshi Yamamoto, Junya Shirai, Tsuneo Oda, Takashi Imada, Mitsunori Kono, Ayumu Sato, Yoshihide Tomata, Atsuko Ochida, Naoki Ishii, Yusuke Sasaki, Yoshiyuki Fukase, Tomoya Yukawa, Shoji Fukumoto